Posted on October 11, 2024
We were thrilled to participate in the 2024 Undergraduate Research Fair (Thursday, October 10th) and can’t wait to learn more about aspiring researchers! The fair offered students an excellent opportunity to learn more about the exciting work at the Mouse Biology Program, from cutting-edge genetic research to advancing biomedical discoveries.…Read more
Posted on October 4, 2024
A recent study highlights the importance of confirming gene disruption in knockout mice that use the "knockout-first" allele design. This approach, developed by the International Knockout Mouse Consortium, incorporates the En2 splice acceptor sequence and the lacZ reporter gene to facilitate gene function studies. While intended to disrupt gene function…Read more
Posted on February 14, 2024
A groundbreaking study at the University of Texas at Austin, highlighted by NIH Director Dr. Monica M. Bertagnolli, has brought new hope to the treatment of neuropathic pain, thanks to the utilization of KOMP (Knockout Mouse Project) mice modified by the Mouse Biology Program at UC Davis. This NIH-funded research…Read more
Posted on January 2, 2024
The year (2022-2023) marks 24 years since the UC Davis Mouse Biology Program (MBP) began serving the mouse modeling needs of the campus community. Now entering its 25th year, the MBP remains the only one-stop in-house resource of unique expertise, services, and training in the creation, testing, and application of mouse models…Read more
Posted on August 28, 2023
Mouse Biology Program is in the process of an across the board rate review, affecting MBP, MMRRC at UC Davis, MMPC-Live at UC Davis, GMRC, and MBSR. Our rates will be updated as early as October 1, 2023. Orders submitted prior to that date will not be affected, however fees…Read more
Posted on May 2, 2023
Imagine the genome as a city with different neighborhoods, each having its function. Topologically associating domain (TAD) boundaries are like the fences that separate these neighborhoods, maintaining distinct regulatory territories. Disruption of these boundaries may interfere with regular gene expression and cause diseases, but the full impact remains unclear. Researchers…Read more
Posted on April 3, 2023
Mutant mouse genetic modifications have revolutionized biomedical research, enabling scientists to study specific gene mutations and their effects on biological processes. This study used data mining to investigate congenital abnormalities underlying the Microphthalmia, Anophthalmia, and Coloboma (MAC) spectrum disease, a group of eye malformations that cause childhood visual impairment. The…Read more
Posted on January 24, 2023
By Claudia Coons The UC Davis Health Department of Surgery has received $3.75 million to launch a high-profile center where researchers can study metabolic disorders using mouse models. The goal is to learn more about the same diseases in humans. The National Center for Metabolic Phenotyping of Mouse Models of Obesity and…Read more
Posted on August 5, 2020
By Andy Fell on August 3, 2020, in Human & Animal Health The National Institutes of Health has awarded a grant of $1.2 million to the Mouse Biology Program at the University of California, Davis, to create mice that are susceptible to the COVID-19 virus. The goal is to create mice…Read more
Posted on May 1, 2020
It is well understood in biomedical research community that mice are a preferred mammalian disease model because of their high genetic homology with humans, rapid reproduction, efficient housing and husbandry, easily characterized phenotypes, and well developed resources and tools for genetic manipulation. As the need for genetically engineered mice grows…Read more
