Papers by hwee ming cheng
Arthritis & Rheumatism, 1997
... Letter. You have full text access to this OnlineOpen article T cell help and antiphospholipid... more ... Letter. You have full text access to this OnlineOpen article T cell help and antiphospholipid antibody immunogenesis. Hwee-Ming Cheng MD 1 ,; Christine Hu MPhil 2 ,; Yehuda Shoenfeld MD 3. Article first published online: 12 DEC 2005. DOI: 10.1002/art.1780400132. ...
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... SL Tung/HM Cheng/CK Sam/and K. Sundram6 •'Institute of Postgraduate Studies, University ... more ... SL Tung/HM Cheng/CK Sam/and K. Sundram6 •'Institute of Postgraduate Studies, University of Malaya, Kuala Lumpur, Malaysia ^ Division of Nutrition, Malaysian Palm Oil Board, Malaysia Introduction Oxysterols are the oxidation products of ... 18. Vine, DF, Mamo, CL, Beilin. ...
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BLDE University Journal of Health Sciences
When we talk about conceptual learning, we also think about certain principles in physiology that... more When we talk about conceptual learning, we also think about certain principles in physiology that recur in various organ systems in the body. These global underlying themes are like the Lego building blocks when we look at the mechanics of physiological processes. One main?” PhysioLego” concept of building brick is the relationship between membrane selective permeability and effective osmotic pressure. This is expressed in laboratory class demonstration by saying that the tonicity of a solution is dependent on not just the osmotic concentration but also importantly on the membrane penetrability of the solute in solution. The “PhysioLego” osmotic bricks and its construction to build an integrated understanding of physiology and pathophysiology will be described in this article.
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Frontiers in Pharmacology
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BMC Complementary and Alternative Medicine, 2015
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American journal of hypertension, 2000
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Asian Pacific journal of allergy and immunology / launched by the Allergy and Immunology Society of Thailand, 2005
The antibody levels to viral capsid antigen (VCA) and early antigen (EA) of Epstein-Barr virus (E... more The antibody levels to viral capsid antigen (VCA) and early antigen (EA) of Epstein-Barr virus (EBV) in 164 nasopharyngeal carcinoma (NPC) patients from Sarawak, East Malaysia were significantly higher than those in 147 sex, age and ethnically matched healthy controls. As diagnostic markers of NPC, IgG/VCA at reciprocal titers > or =160 was the most sensitive (89%, with 98% specificity), while IgA/EA at > or =5 was the most specific (100%) but the least sensitive (75%). The sensitivity and specificity of IgA/VCA at reciprocal titers > or =10 were 84% and 97%. IgA/VCA has an advantage over IgG/VCA despite the slightly lower sensitivity due to its consistently more distinct fluorescence reaction. The sensitivity and specificity can be marginally improved by a combination of two tests.
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Immunology Today, 1998
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Thrombosis Research, 1992
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Nutrition Research, 2007
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Nutrition Journal, 2012
Background Tocotrienols (T3) and tocopherols (T), both members of the natural vitamin E family ha... more Background Tocotrienols (T3) and tocopherols (T), both members of the natural vitamin E family have unique biological functions in humans. T3 are detected in circulating human plasma and lipoproteins, although at concentrations significantly lower than α-tocopherol (α-T). T3, especially α-T3 is known to be neuropotective at nanomolar concentrations and this study evaluated the postprandial fate of T3 and α-T in plasma and lipoproteins. Methods Ten healthy volunteers (5 males and 5 females) were administered a single dose of vitamin E [526 mg palm tocotrienol-rich fraction (TRF) or 537 mg α-T] after 7-d pre-conditioning on a T3-free diet. Blood was sampled at baseline (fasted) and 2, 4, 5, 6, 8, and 24 h after supplementation. Concentrations of T and T3 isomers in plasma, triacylglycerol-rich particles (TRP), LDL, and HDL were measured at each postprandial interval. Results After TRF supplementation, plasma α-T3 and γ-T3 peaked at 5 h (α-T3: 4.74 ± 1.69 μM; γ-T3: 2.73 ± 1.27 μM). δ-T...
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Molecules, 2010
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Lipids, 2010
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Lipids, 2011
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Journal of Immunological Methods, 1988
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Immunology Letters, 1990
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Immunological Investigations, 1989
Non-reactive SLE sera in an ELISA for anticardiolipin antibody (aCL) retested positive in the imm... more Non-reactive SLE sera in an ELISA for anticardiolipin antibody (aCL) retested positive in the immunoassay when the sera were first heat-inactivated at 56 degrees C for 30 minutes. This was not a false positive phenomenon since the positive ELISA reactivity of the heated SLE sera was markedly reduced by inhibition with the cardiolipin antigen. Furthermore, the heat-potentiated ELISA reaction was abolished by prior IgG depletion of the SLE sera with Protein A preparation. The unmasked aCL in the heat-treated SLE sera also exhibited selective binding in ELISA to other negatively-charged phospholipids, namely phosphatidylserine and phosphatidic acid but not against either phosphatidylcholine or phosphatidyl-ethanolamine. The data strongly indicate an interaction between antiphospholipid antibodies and heat-sensitive serum component(s), a reduction of the latter resulting in the ELISA detection of the autoantibody.
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Cancer Immunology Immunotherapy, 1994
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British Journal of Haematology, 1989
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Clinical …, 2002
Abstract: The aim of this study was to investigate the incidence of IgG anticardiolipin antibody ... more Abstract: The aim of this study was to investigate the incidence of IgG anticardiolipin antibody (ACL) and IgG anti-β2 glycoprotein I antibody (anti-β2GPI) positivity in patients with primary or secondary anti-phospholipid syndrome (APS) and systemic lupus erythematosus (SLE), ...
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