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ATR inhibition selectively sensitizes G1 checkpoint-deficient cells to lethal premature chromatin condensation
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1 reference
stated in
Europe PubMed Central
PMC publication ID
55378
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11481475%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 May 2020
title
ATR inhibition selectively sensitizes G1 checkpoint-deficient cells to lethal premature chromatin condensation
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
55378
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11481475%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 May 2020
author
Paul Nghiem
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
55378
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11481475%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 May 2020
author name string
P K Park
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
55378
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11481475%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 May 2020
Y Kim
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
55378
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11481475%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 May 2020
C Vaziri
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
55378
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11481475%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 May 2020
S L Schreiber
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
55378
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11481475%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 May 2020
publication date
1 July 2001
1 reference
stated in
Europe PubMed Central
PMC publication ID
55378
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11481475%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 May 2020
published in
Proceedings of the National Academy of Sciences of the United States of America
1 reference
stated in
Europe PubMed Central
PMC publication ID
55378
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11481475%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 May 2020
volume
98
1 reference
stated in
Europe PubMed Central
PMC publication ID
55378
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11481475%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 May 2020
issue
16
1 reference
stated in
Europe PubMed Central
PMC publication ID
55378
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11481475%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 May 2020
page(s)
9092-9097
1 reference
stated in
Europe PubMed Central
PMC publication ID
55378
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11481475%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 May 2020
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ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway
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ATR disruption leads to chromosomal fragmentation and early embryonic lethality
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ATR is a caffeine-sensitive, DNA-activated protein kinase with a substrate specificity distinct from DNA-PK.
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Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine.
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The ataxia-telangiectasia related protein ATR mediates DNA-dependent phosphorylation of p53.
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The PIK-related kinases intercept conventional signaling pathways
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Abrogation of the G2 checkpoint results in differential radiosensitization of G1 checkpoint-deficient and G1 checkpoint-competent cells
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Identifiers
DOI
10.1073/PNAS.161281798
1 reference
stated in
Europe PubMed Central
PMC publication ID
55378
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11481475%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 May 2020
ADS bibcode
2001PNAS...98.9092N
0 references
PMC publication ID
55378
1 reference
stated in
Europe PubMed Central
PMC publication ID
55378
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11481475%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 May 2020
PubMed publication ID
11481475
1 reference
stated in
Europe PubMed Central
PMC publication ID
55378
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11481475%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 May 2020
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