(Q909381)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9HBE4

1 reference

13 November 2019

1 reference

13 November 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBE4

1 reference

8 April 2019

interleukin-2 receptor binding

IPI

1 reference

8 April 2019

Human IL-21 and IL-4 bind to partially overlapping epitopes of common gamma-chain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBE4

intracellular anatomical structure

IPI

cell component

1 reference

10 September 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HBE4&geneProductId=UniProtKB:Q9HBE4

extracellular space

Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBE4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBE4

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBE4

8 April 2019

extracellular region

positive regulation of inflammatory response

TAS

biological process

1 reference

8 April 2019

Divergent effects of IL-12 and IL-23 on the production of IL-17 by human T cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBE4

positive regulation of cytokine production

1 reference

8 April 2019

Il-21 enhances NK cell activation and cytolytic activity and induces Th17 cell differentiation in inflammatory bowel disease

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBE4

cell maturation

1 reference

8 April 2019

IL-21 induces both rapid maturation of human CD34+ cell precursors towards NK cells and acquisition of surface killer Ig-like receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBE4

positive regulation of B cell proliferation

1 reference

8 April 2019

Cloning and characterization of an isoform of interleukin-21

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBE4

positive regulation of tissue remodeling

1 reference

8 April 2019

Divergent effects of IL-12 and IL-23 on the production of IL-17 by human T cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBE4

immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBE4

1 reference

8 April 2019

positive regulation of cell population proliferation

1 reference

8 April 2019

Cloning and characterization of an isoform of interleukin-21

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBE4

positive regulation of interleukin-17 production

1 reference

8 April 2019

Divergent effects of IL-12 and IL-23 on the production of IL-17 by human T cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBE4

positive regulation of natural killer cell mediated cytotoxicity

1 reference

8 April 2019

Interleukin-21 activates human natural killer cells and modulates their surface receptor expression

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBE4

signal transduction

NAS

1 reference

8 April 2019

Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBE4

tyrosine phosphorylation of STAT protein

NAS

1 reference

8 April 2019

IL-21 up-regulates the expression of genes associated with innate immunity and Th1 response

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBE4

positive regulation of tyrosine phosphorylation of STAT protein

1 reference

8 April 2019

Cloning and characterization of an isoform of interleukin-21

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBE4

regulation of signaling receptor activity

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBE4

interleukin-21-mediated signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HBE4

1 reference

8 April 2019

https://docs.openalex.org/download-snapshot/snapshot-data-format

TAS

Gene Atlas image

PBB GE IL21 221271 at fs.png
732 × 530; 12 KB

0 references

Identifiers

MeSH descriptor ID

C416243

subject named as

interleukin-21

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

28 October 2013

Microsoft Academic ID

0 references

1 reference

26 January 2022

1 reference

9 August 2016

language of work or name

1 reference

9 August 2016

language of work or name

1 reference

inferred by common MeSH mappings on source and on Wikidata

UMLS 2023