(Q905736)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P43119

GPCR, rhodopsin-like, 7TM, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

signal transducer activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P43119&geneProductId=UniProtKB:P43119

1 reference

27 March 2018

guanyl-nucleotide exchange factor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43119

1 reference

9 May 2019

prostacyclin receptor activity

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43119

cell component

cytosol

1 reference

9 May 2019

Smooth muscle proliferation and role of the prostacyclin (IP) receptor in idiopathic pulmonary arterial hypertension

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43119

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43119

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43119

8 April 2019

8 April 2019

Smooth muscle proliferation and role of the prostacyclin (IP) receptor in idiopathic pulmonary arterial hypertension

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43119

integral component of plasma membrane

1 reference

9 May 2019

Cloning and expression of a cDNA for the human prostanoid IP receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43119

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43119

1 reference

9 May 2019

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43119

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43119

9 May 2019

9 May 2019

Smooth muscle proliferation and role of the prostacyclin (IP) receptor in idiopathic pulmonary arterial hypertension

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43119

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43119

biological process

cell-cell signaling

1 reference

9 May 2019

Cloning and expression of a cDNA for the human prostanoid IP receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43119

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

1 reference

9 May 2019

Cloning and expression of a cDNA for the human prostanoid IP receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43119

response to lipopolysaccharide

Ensembl genome database project

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43119

signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43119

1 reference

9 May 2019

G protein-coupled receptor signaling pathway

inflammatory response

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43119

adenylate cyclase-activating G protein-coupled receptor signaling pathway

Smooth muscle proliferation and role of the prostacyclin (IP) receptor in idiopathic pulmonary arterial hypertension

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43119

Ensembl genome database project

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43119

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43119

positive regulation of cytosolic calcium ion concentration

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43119

negative regulation of smooth muscle cell proliferation

Ensembl genome database project

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43119

9 May 2019

Smooth muscle proliferation and role of the prostacyclin (IP) receptor in idiopathic pulmonary arterial hypertension

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43119

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43119

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

1882

language of work or name

17 August 2016

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

5820

language of work or name

17 August 2016

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

1888

language of work or name

English

object of statement has role

17 August 2016

selexipag

agonist

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL238804

iloprost

object of statement has role

agonist

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL494

esuberaprost

object of statement has role

agonist

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL3137314

Gene Atlas image

PBB GE PTGIR 206187 at fs.png
732 × 530; 11 KB

0 references

has part(s)

GPCR, rhodopsin-like, 7TM

1 reference

InterPro Release 71.0