(Q84972171)
English
PKC-gamma calcium signaling pathway in ataxia
PKC-gamma calcium-signaling pathway in Ataxia. Upon ligand binding, the mGluR1 receptor is followed by activation of Gq causing PLC-mediated hydrolysis of PIP2 into IP3 and DAG. Binding of IP3 to the IP3R1 induces Ca2+ release from the endoplasm...
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