Address
:
[go:
up one dir
,
main page
]
Include Form
Remove Scripts
Session Cookies
Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q74083363)
Watch
English
The c-MYC allele that is translocated into the IgH locus undergoes constitutive hypermutation in a Burkitt's lymphoma line
scientific article published on 01 July 2000
In more languages
default for all languages
No label defined
No description defined
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10918597
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10918597%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
title
The c-MYC allele that is translocated into the IgH locus undergoes constitutive hypermutation in a Burkitt's lymphoma line
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10918597
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10918597%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
author name string
Bemark M
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10918597
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10918597%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
Neuberger MS
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10918597
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10918597%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
language of work or name
English
0 references
publication date
1 July 2000
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10918597
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10918597%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
published in
Oncogene
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10918597
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10918597%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
volume
19
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10918597
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10918597%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
issue
30
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10918597
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10918597%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
page(s)
3404-3410
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10918597
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10918597%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
cites work
A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sequence of the murine and human cellular myc oncogenes and two modes of myc transcription resulting from chromosome translocation in B lymphoid tumours.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the first exon are associated with altered transcription of c-myc in Burkitt lymphoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The c-myc gene encodes superimposed RNA polymerase II and III promoters
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mismatch repair deficiency interferes with the accumulation of mutations in chronically stimulated B cells and not with the hypermutation process
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Somatic hypermutation in the heavy chain locus correlates with transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cells strongly expressing Ig(kappa) transgenes show clonal recruitment of hypermutation: a role for both MAR and the enhancers.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
c-Myc proteolysis by the ubiquitin-proteasome pathway: stabilization of c-Myc in Burkitt's lymphoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Translocation joins c-myc and immunoglobulin gamma 1 genes in a Burkitt lymphoma revealing a third exon in the c-myc oncogene.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
c-mycHypermutation in Burkitt's Lymphoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional pause, arrest and termination sites for RNA polymerase II in mammalian N- and c-myc genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intrinsic sites of transcription termination and pausing in the c-myc gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Frequent somatic hypermutation of the 5' noncoding region of the BCL6 gene in B-cell lymphoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Somatic mutation and transcriptional deregulation of myc in endemic Burkitt's lymphoma disease: heptamer-nonamer recognition mistakes?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Persistence of immunoglobulin heavy chain/c-myc recombination-positive lymphocyte clones in the blood of human immunodeficiency virus-infected homosexual men
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reciprocal chromosome translocation between c-myc and immunoglobulin gamma 2b genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Somatic hypermutation of immunoglobulin genes is linked to transcription initiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A second B cell-specific enhancer 3' of the immunoglobulin heavy-chain locus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcription enhancer identified near the human C mu immunoglobulin heavy chain gene is unavailable to the translocated c-myc gene in a Burkitt lymphoma.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of somatic mutation within translocated c-myc genes in Burkitt's lymphoma.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Altered nucleotide sequences of a translocated c-myc gene in Burkitt lymphoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The 5' hypermutation boundary of kappa chains is independent of local and neighbouring sequences and related to the distance from the initiation of transcription.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MYC oncogene involved in a t(8;22) chromosome translocation is not altered in its putative regulatory regions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The block to transcription elongation is promoter dependent in normal and Burkitt's lymphoma c-myc alleles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Allele-specific activation of the c-myc gene in an atypical Burkitt's lymphoma carrying the t(2;8) chromosomal translocation 250 kb downstream from c-myc
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation and somatic mutation of the translocated c-myc gene in burkitt lymphoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of the cis-acting elements required for somatic hypermutation of murine antibody V genes using conventional transgenic and transgene homologous recombination approaches
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The transcriptional promoter regulates hypermutation of the antibody heavy chain locus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Somatic hypermutation of Ig genes in patients with xeroderma pigmentosum (XP-D)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Somatic hypermutation of immunoglobulin genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Somatic hypermutation introduces insertions and deletions into immunoglobulin V genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of a translocated c-myc gene: role of structural alterations in the upstream region
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeting of non-Ig sequences in place of the V segment by somatic hypermutation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A point mutation in the c-myc locus of a Burkitt lymphoma abolishes binding of a nuclear protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203686
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.ONC.1203686
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10918597
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10918597%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
Dimensions Publication ID
1022896826
0 references
PubMed publication ID
10918597
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10918597
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10918597%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit