(Q73580418)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12829011%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

title

Is loss of function of the prion protein the cause of prion disorders? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12829011%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Claudio Hetz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12829011%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Kinsey Maundrell

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12829011%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Claudio Soto

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12829011%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

publication date

1 June 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12829011%20AND%20SRC:MED&resulttype=core&format=json

Trends in Molecular Medicine

5 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12829011%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12829011%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12829011%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

page(s)

237-243

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12829011%20AND%20SRC:MED&resulttype=core&format=json

Prion diseases of humans and animals: their causes and molecular basis

5 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

1 reference

7 January 2021

Prion Protein Biology

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Pathologic conformations of prion proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Neuropathological diagnostic criteria for Creutzfeldt-Jakob disease (CJD) and other human spongiform encephalopathies (prion diseases).

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Vacuolation in murine prion disease: an informative artifact.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Neuronal apoptosis in Creutzfeldt-Jakob disease

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Evidence for an early inflammatory response in the central nervous system of mice with scrapie.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Prion protein amyloidosis

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Pathology of the transmissible spongiform encephalopathies with special emphasis on ultrastructure

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Signal transduction through prion protein

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

PrPC directly interacts with proteins involved in signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Identification of a 60-kilodalton stress-related protein, p60, which interacts with hsp90 and hsp70

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Stress-inducible, murine protein mSTI1. Characterization of binding domains for heat shock proteins and in vitro phosphorylation by different kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Cellular prion protein transduces neuroprotective signals

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Neurotoxicity of a prion protein fragment

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Molecular characteristics of a protease-resistant, amyloidogenic and neurotoxic peptide homologous to residues 106-126 of the prion protein

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Prion protein peptides induce alpha-helix to beta-sheet conformational transitions

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Mouse cortical cells lacking cellular PrP survive in culture with a neurotoxic PrP fragment

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Prions prevent neuronal cell-line death.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Interaction of prion proteins with cell surface receptors, molecular chaperones, and other molecules

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Analysis of interaction sites in homo- and heteromeric complexes containing Bcl-2 family members and the cellular prion protein

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Prion protein protects human neurons against Bax-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Prion protein devoid of the octapeptide repeat region restores susceptibility to scrapie in PrP knockout mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Copper and prion disease

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Clinical and histological recovery from the scrapie-like spongiform encephalopathy produced in mice by feeding them with cuprizone

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Spongiform encephalopathy induced in rats and guinea pigs by cuprizone

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Prion protein binds copper within the physiological concentration range

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

B lymphocytes and neuroinvasion

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Normal prion protein has an activity like that of superoxide dismutase.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Brain copper content and cuproenzyme activity do not vary with prion protein expression level

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Metal imbalance and compromised antioxidant function are early changes in prion disease

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Oxidative impairment in scrapie-infected mice is associated with brain metals perturbations and altered antioxidant activities

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Aberrant metal binding by prion protein in human prion disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Synthesis and trafficking of prion proteins in cultured cells

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Copper stimulates endocytosis of the prion protein

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Copper(II)-induced conformational changes and protease resistance in recombinant and cellular PrP. Effect of protein age and deamidation

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

A transmembrane form of the prion protein in neurodegenerative disease

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Transmissible and genetic prion diseases share a common pathway of neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Conversion of PrP to a self-perpetuating PrPSc-like conformation in the cytosol

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Small is not beautiful: antagonizing functions for the prion protein PrP(C) and its homologue Dpl.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Differences between the prion protein and its homolog Doppel: a partially structured state with implications for scrapie formation

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

The PrP-like protein Doppel gene in sheep and cattle: cDNA sequence and expression

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Absence of the prion protein homologue Doppel causes male sterility

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Doppel-induced cerebellar degeneration in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Normal neurogenesis and scrapie pathogenesis in neural grafts lacking the prion protein homologue Doppel

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Expression of doppel in the CNS of mice does not modulate transmissible spongiform encephalopathy disease

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Post-natal knockout of prion protein alters hippocampal CA1 properties, but does not result in neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

Lack of prion protein expression results in a neuronal phenotype sensitive to stress

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900069-8

7 January 2021

10.1016/S1471-4914(03)00069-8

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12829011%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12829011%20AND%20SRC:MED&resulttype=core&format=json