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CD4+ T cell survival is not directly linked to self-MHC-induced TCR signaling
scientific article published on 01 October 2000
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1 reference
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Europe PubMed Central
PubMed publication ID
11017105
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11017105%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
title
CD4+ T cell survival is not directly linked to self-MHC-induced TCR signaling
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11017105
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11017105%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
author name string
Dorfman JR
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11017105
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11017105%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
Stefanová I
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11017105
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11017105%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
Yasutomo K
series ordinal
3
1 reference
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Europe PubMed Central
PubMed publication ID
11017105
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11017105%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
Germain RN
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11017105
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11017105%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
publication date
1 October 2000
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11017105
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11017105%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
published in
Nature Immunology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11017105
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11017105%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
volume
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11017105
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11017105%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
issue
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11017105
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11017105%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
page(s)
329-335
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11017105
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11017105%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
cites work
Lower receptor avidity required for thymic clonal deletion than for effector T-cell function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Altered peptide ligands induce quantitatively but not qualitatively different intracellular signals in primary thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Preselection thymocytes are more sensitive to T cell receptor stimulation than mature T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Divergent changes in the sensitivity of maturing T cells to structurally related ligands underlies formation of a useful T cell repertoire
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MHC Class II Molecules Are Not Required for Survival of Newly Generated CD4+ T Cells, but Affect Their Long-Term Life Span
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential requirements for survival and proliferation of CD8 naïve or memory T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted complementation of MHC class II deficiency by intrathymic delivery of recombinant adenoviruses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Survival of mature CD4 T lymphocytes is dependent on major histocompatibility complex class II-expressing dendritic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Long-term T cell memory requires the surface expression of self-peptide/major histocompatibility complex molecules
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Designing and maintaining the mature TCR repertoire: the continuum of self-peptide:self-MHC complex recognition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tetracycline-controllable selection of CD4(+) T cells: half-life and survival signals in the absence of major histocompatibility complex class II molecules
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TCR-MHC class II interaction is required for peripheral expansion of CD4 cells in a T cell-deficient host.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Naïve cytotoxic T lymphocytes spontaneously acquire effector function in lymphocytopenic recipients: A pitfall for T cell memory studies?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD4+ T cell division in irradiated mice requires peptides distinct from those responsible for thymic selection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Low-affinity ligands for the TCR drive proliferation of mature CD8+ T cells in lymphopenic hosts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homeostatic expansion and phenotypic conversion of naïve T cells in response to self peptide/MHC ligands
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Persistence of memory CD8 T cells in MHC class I-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mature CD4+ T Cells Perceive a Positively Selecting Class II MHC/Peptide Complex in the Periphery
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutive Tyrosine Phosphorylation of the T-Cell Receptor (TCR) ζ Subunit: Regulation of TCR-Associated Protein Tyrosine Kinase Activity by TCR ζ
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ZAP-70 is constitutively associated with tyrosine-phosphorylated TCR ζ in murine thymocytes and lymph node T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Partial T cell signaling: altered phospho-zeta and lack of zap70 recruitment in APL-induced T cell anergy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cell memory
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peripheral selection of the T cell repertoire
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Memory/effector T cells in TCR transgenic mice develop via recognition of enteric antigens by a second, endogenous TCR.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crippling of CD3-ζ ITAMs Does Not Impair T Cell Receptor Signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of the multiple T cell receptor (TCR)-zeta chain signaling motifs in selection of the T cell repertoire
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Restoration of T-cell homeostasis after T-cell depletion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Positive selection of T cells: rescue from programmed cell death and differentiation require continual engagement of the T cell receptor.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two separable T cell receptor signals reconstitute positive selection of CD4 lineage T cells in vivo.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TCR signaling for initiation and completion of thymocyte positive selection has distinct requirements for ligand quality and presenting cell type.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intrathymic signalling in immature CD4+ CD8+ thymocytes results in tyrosine phosphorylation of the T-cell receptor zeta chain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective events in T cell development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of the CD4-major histocompatibility complex class II interaction blocks the development of CD4(+) T cells in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MHC class II interaction with CD4 mediated by a region analogous to the MHC class I binding site for CD8
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice lacking MHC class II molecules
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Survival and homeostatic proliferation of naive peripheral CD4+ T cells in the absence of self peptide:MHC complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peripheral selection of T cell repertoires: the role of continuous thymus output
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inactivation of misselected CD8 T cells by CD8 gene methylation and cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential reactivity of residual CD8+ T lymphocytes in TAP1 and beta 2-microglobulin mutant mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reactivity and specificity of CD8+ T cells in mice with defects in the MHC class I antigen-presenting pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antiproliferative action of interferon-α requires components of T-cell-receptor signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of interleukin 2 signaling and signal transducer and activator of transcription (STAT)5 activation during T cell receptor-mediated feedback inhibition of T cell expansion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation of TCR signaling by beta1 integrins: role of the tyrosine phosphatase SHP-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The dynamics of T cell receptor signaling: complex orchestration and the key roles of tempo and cooperation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homeostasis of alpha beta TCR+ T cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adaptive cellular interactions in the immune system: the tunable activation threshold and the significance of subthreshold responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Partially phosphorylated T cell receptor zeta molecules can inhibit T cell activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Beta 2-microglobulin deficient mice lack CD4-8+ cytolytic T cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4-8+ T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F79783
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/79783
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11017105
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11017105%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
PubMed publication ID
11017105
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11017105
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11017105%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
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