(Q59303878)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16221894%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

title

Evidence for purifying selection against synonymous mutations in mammalian exonic splicing enhancers (English)

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8 January 2020

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8 January 2020

Joanna L Parmley

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8 January 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16221894%20AND%20SRC:MED&resulttype=core&format=json

J V Chamary

series ordinal

object named as

J V Chamary

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8 January 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16221894%20AND%20SRC:MED&resulttype=core&format=json

publication date

12 October 2005

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Molecular Biology and Evolution

8 January 2020

published in

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8 January 2020

volume

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8 January 2020

issue

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8 January 2020

page(s)

301-309

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Translational selection and molecular evolution

8 January 2020

cites work

1 reference

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DNA methylation and the frequency of CpG in animal DNA.

21 January 2018

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Exonic splicing enhancers: mechanism of action, diversity and role in human genetic diseases

21 January 2018

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Synonymous nucleotide substitution rates in mammalian genes: implications for the molecular clock and the relationship of mammalian orders

21 January 2018

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A maximum likelihood method for analyzing pseudogene evolution: implications for silent site evolution in humans and rodents

21 January 2018

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A synonymous SNP of the corneodesmosin gene leads to increased mRNA stability and demonstrates association with psoriasis across diverse ethnic groups

21 January 2018

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21 January 2018

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Biased codon usage near intron-exon junctions: selection on splicing enhancers, splice-site recognition or something else?

21 January 2018

1 reference

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Evidence for selection on synonymous mutations affecting stability of mRNA secondary structure in mammals

21 January 2018

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Inferring nonneutral evolution from human-chimp-mouse orthologous gene trios

21 January 2018

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Selective and mutational patterns associated with gene expression in humans: influences on synonymous composition and intron presence

21 January 2018

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Cytosine methylation and the fate of CpG dinucleotides in vertebrate genomes.

21 January 2018

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Identification of a new class of exonic splicing enhancers by in vivo selection

21 January 2018

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Solving the riddle of codon usage preferences: a test for translational selection

21 January 2018

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Mammalian mutation pressure, synonymous codon choice, and mRNA degradation

21 January 2018

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Synonymous mutations in the human dopamine receptor D2 (DRD2) affect mRNA stability and synthesis of the receptor

21 January 2018

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Evolution of synonymous codon usage in metazoans

21 January 2018

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Natural selection affects frequencies of AG and GT dinucleotides at the 5' and 3' ends of exons

21 January 2018

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An analysis of codon usage in mammals: selection or mutation bias?

21 January 2018

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High genomic deleterious mutation rates in hominids

21 January 2018

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Human genomic sequences that inhibit splicing

21 January 2018

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Single nucleotide polymorphism-based validation of exonic splicing enhancers

21 January 2018

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Predictive identification of exonic splicing enhancers in human genes

21 January 2018

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RESCUE-ESE identifies candidate exonic splicing enhancers in vertebrate exons

21 January 2018

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A systematic analysis of the factors that determine the strength of pre-mRNA splicing enhancers.

21 January 2018

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Selection on Human Genes as Revealed by Comparisons to Chimpanzee cDNA

21 January 2018

1 reference

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A test of translational selection at 'silent' sites in the human genome: base composition comparisons in alternatively spliced genes.

21 January 2018

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Deleterious mutations and the evolution of sex.

21 January 2018

1 reference

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Functional constraints and frequency of deleterious mutations in noncoding DNA of rodents

21 January 2018

1 reference

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Preponderance of synonymous changes as evidence for the neutral theory of molecular evolution

21 January 2018

1 reference

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21 January 2018

Non-Darwinian Evolution

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Gene splice sites correlate with nucleosome positions

21 January 2018

1 reference

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Codon bias as a factor in regulating expression via translation rate in the human genome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ035

Genomic regionality in rates of evolution is not explained by clustering of genes of comparable expression profile

21 January 2018

1 reference

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Unbiased estimation of the rates of synonymous and nonsynonymous substitution

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ035

A computational analysis of sequence features involved in recognition of short introns

21 January 2018

1 reference

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A mechanism for exon skipping caused by nonsense or missense mutations in BRCA1 and other genes

21 January 2018

1 reference

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Identification of functional exonic splicing enhancer motifs recognized by individual SR proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ035

Nucleotide Frequency Variation Across Human Genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ035

Weak selection revealed by the whole-genome comparison of the X chromosome and autosomes of human and chimpanzee

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ035

Distribution and characterization of regulatory elements in the human genome

21 January 2018

1 reference

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De novo insertion of an intron into the mammalian sex determining gene, SRY.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ035

Synonymous mutations in CFTR exon 12 affect splicing and are not neutral in evolution.

21 January 2018

1 reference

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Site-to-site variation of synonymous substitution rates

21 January 2018

1 reference

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Exon definition may facilitate splice site selection in RNAs with multiple exons

21 January 2018

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Large-scale comparison of intron positions in mammalian genes shows intron loss but no gain

21 January 2018

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Selection and characterization of pre-mRNA splicing enhancers: identification of novel SR protein-specific enhancer sequences

21 January 2018

1 reference

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DNA sequence evolution: the sounds of silence

21 January 2018

1 reference

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Regulation of alternative splicing by PTB and associated factors.

21 January 2018

1 reference

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The expected equilibrium of the CpG dinucleotide in vertebrate genomes under a mutation model

21 January 2018

1 reference

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Selection of novel exon recognition elements from a pool of random sequences

21 January 2018

1 reference

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The signature of selection mediated by expression on human genes

21 January 2018

1 reference

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Systematic identification and analysis of exonic splicing silencers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ035

Evidence for codon bias selection at the pre-mRNA level in eukaryotes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ035

Evidence of functional selection pressure for alternative splicing events that accelerate evolution of protein subsequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ035

Variation in sequence and organization of splicing regulatory elements in vertebrate genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ035

Identification and analysis of alternative splicing events conserved in human and mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSJ035

21 January 2018

Identifiers

DOI

10.1093/MOLBEV/MSJ035

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16221894%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16221894%20AND%20SRC:MED&resulttype=core&format=json