(Q58853821)

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The Functional Microdomain in Transmembrane Helices 2 and 7 Regulates Expression, Activation, and Coupling Pathways of the Gonadotropin-releasing Hormone Receptor

scientific article published in Journal of Biological Chemistry

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31 October 2019

The functional microdomain in transmembrane helices 2 and 7 regulates expression, activation, and coupling pathways of the gonadotropin-releasing hormone receptor (English)

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Europe PubMed Central

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31 October 2019

transmembrane protein

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Colleen A Flanagan

1

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31 October 2019

Robert P. Millar

9

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31 October 2019

Harel Weinstein

10

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31 October 2019

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W Zhou

2

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31 October 2019

L Chi

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31 October 2019

T Yuen

4

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31 October 2019

V Rodic

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31 October 2019

D Robertson

6

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31 October 2019

M Johnson

7

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31 October 2019

P Holland

8

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31 October 2019

R Mitchell

11

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31 October 2019

S C Sealfon

12

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31 October 2019

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1 October 1999

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31 October 2019

Journal of Biological Chemistry

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31 October 2019

274

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31 October 2019

41

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31 October 2019

28880-28886

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31 October 2019

Molecular mechanisms of ligand interaction with the gonadotropin-releasing hormone receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.28880

21 January 2018

Sequence alignment of the G-protein coupled receptor superfamily

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.28880

21 January 2018

Functional Microdomains in G-protein-coupled Receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.28880

21 January 2018

Projection structure of rhodopsin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.28880

21 January 2018

Projection structure of frog rhodopsin in two crystal forms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.28880

21 January 2018

Functional role of the spatial proximity of Asp114(2.50) in TMH 2 and Asn332(7.49) in TMH 7 of the mu opioid receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.28880

21 January 2018

Conserved polar residues in the transmembrane domain of the human tachykinin NK2 receptor: functional roles and structural implications

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.28880

21 January 2018

Effects of Asn87 and Asp318 mutations on ligand binding and signal transduction in the rat GnRH receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.28880

21 January 2018

Differences in structure-function relations between nonmammalian and mammalian gonadotropin-releasing hormone receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.28880

21 January 2018

Two gonadotropin-releasing hormone receptor subtypes with distinct ligand selectivity and differential distribution in brain and pituitary in the goldfish (Carassius auratus)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.28880

21 January 2018

A proposed structure for transmembrane segment 7 of G protein-coupled receptors incorporating an asn-Pro/Asp-Pro motif

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.28880

21 January 2018

Rhodopsin-family receptors associate with small G proteins to activate phospholipase D.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.28880

21 January 2018

A novel human GnRH receptor homolog gene: abundant and wide tissue distribution of the antisense transcript

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.28880

21 January 2018

A Locus of the Gonadotropin-releasing Hormone Receptor That Differentiates Agonist and Antagonist Binding Sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.28880

21 January 2018

Inhibin increases and progesterone decreases receptors for gonadotropin-releasing hormone in ovine pituitary culture

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.28880

21 January 2018

[8] Ligand binding and second-messenger assays for cloned Gq/G11-coupled neuropeptide receptors: The GnRH receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.28880

21 January 2018

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.28880

21 January 2018

Irreversible activation of the gonadotropin-releasing hormone receptor by photoaffinity cross-linking: localization of attachment site to Cys residue in N-terminal segment

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.28880

21 January 2018

Structural instability of a constitutively active G protein-coupled receptor. Agonist-independent activation due to conformational flexibility

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.28880

21 January 2018

Molecular Architecture of G Protein-Coupled Receptors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.28880

21 January 2018

Molecular dynamics simulations of HIV-1 protease with peptide substrate.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.28880

21 January 2018

The structure and function of the aspartic proteinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.28880

21 January 2018

The activation process of the alpha1B-adrenergic receptor: potential role of protonation and hydrophobicity of a highly conserved aspartate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.28880

21 January 2018

A Conserved NPLFY Sequence Contributes to Agonist Binding and Signal Transduction but Is Not an Internalization Signal for the Type 1 Angiotensin II Receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.28880

21 January 2018

Identification of transmembrane domain residues determinant in the structure-function relationship of the human platelet-activating factor receptor by site-directed mutagenesis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.28880

21 January 2018

A point mutation of the alpha 2-adrenoceptor that blocks coupling to potassium but not calcium currents

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.28880

21 January 2018

Identifiers

10.1074/JBC.274.41.28880

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10506131%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10506131%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

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