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English
The p16INK4a/CDKN2A tumor suppressor and its relatives.
scientific article published in October 1998
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9823374
retrieved
27 May 2018
reference URL
http://europepmc.org/abstract/MED/9823374
review article
1 reference
stated in
Europe PubMed Central
title
The p16INK4a/CDKN2A tumor suppressor and its relatives.
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9823374
retrieved
27 May 2018
reference URL
http://europepmc.org/abstract/MED/9823374
author name string
M Ruas
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9823374
retrieved
27 May 2018
reference URL
http://europepmc.org/abstract/MED/9823374
G Peters
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9823374
retrieved
27 May 2018
reference URL
http://europepmc.org/abstract/MED/9823374
publication date
1 October 1998
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9823374
retrieved
27 May 2018
reference URL
http://europepmc.org/abstract/MED/9823374
published in
Biochimica et Biophysica Acta
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9823374
retrieved
27 May 2018
reference URL
http://europepmc.org/abstract/MED/9823374
volume
1378
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9823374
retrieved
27 May 2018
reference URL
http://europepmc.org/abstract/MED/9823374
issue
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9823374
retrieved
27 May 2018
reference URL
http://europepmc.org/abstract/MED/9823374
page(s)
F115-77
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9823374
retrieved
27 May 2018
reference URL
http://europepmc.org/abstract/MED/9823374
cites work
Aberrations of p16Ink4 and retinoblastoma tumour-suppressor genes occur in distinct sub-sets of human cancer cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deletion analysis of the p16 tumour suppressor gene in phaeochromocytomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic status and expression of the cyclin-dependent kinase inhibitors in human gastric carcinoma cell lines.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Frequent allele loss on 9p21-22 defines a smallest common region in the vicinity of the CDKN2 gene in sporadic breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional analysis of wild-type and malignant glioma derived CDKN2Abeta alleles: evidence for an RB-independent growth suppressive pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Point mutations can inactivate in vitro and in vivo activities of p16(INK4a)/CDKN2A in human glioma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Decreased expression of the p16/MTS1 gene without mutation is frequent in human urinary bladder carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin D1 is a nuclear protein required for cell cycle progression in G1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P16 deletion and mutation analysis in human brain tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The retinoblastoma protein pathway and the restriction point
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduced survival in patients with ductal pancreatic adenocarcinoma associated with CDKN2 mutation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Frequent mutations of CDKN2 in primary pancreatic adenocarcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deletion and differential expression of p16INK4a in mouse lung tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Infrequent CDKN2 (MTS1/p16) gene alterations in human primary breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
G1 control gene status is frequently altered in resectable non-small cell lung cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Frequency of mutation and deletion of the tumor suppressor gene CDKN2A (MTS1/p16) in hepatocellular carcinoma from an Australian population
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CpG-rich islands and the function of DNA methylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural characterization of the tumor suppressor p16, an ankyrin-like repeat protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Open questions on p16
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p16INK4/p15INK4B gene inactivation is a frequent event in malignant T-cell lines.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hundreds of ankyrin-like repeats in functionally diverse proteins: mobile modules that cross phyla horizontally?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor suppressor p16INK4A: determination of solution structure and analyses of its interaction with cyclin-dependent kinase 4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rates of p16 (MTS1) mutations in primary tumors with 9p loss
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Frequency of homozygous deletion at p16/CDKN2 in primary human tumours
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Status and expression of thep16INK4 gene in human thyroid tumors and thyroid-tumor cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loh and mutation analysis ofCDKN2 in primary human ovarian cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Assignment of a locus for familial melanoma, MLM, to chromosome 9p13-p22
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Assignment of the gene for methylthioadenosine phosphorylase to human chromosome 9 by mouse-human somatic cell hybridization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Restoration of CDKN2A into melanoma cells induces morphologic changes and reduction in growth rate but not anchorage-independent growth reversal
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutational analysis of the p16 gene in human neuroblastomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p21 binding to PCNA causes G1 and G2 cell cycle arrest in p53-deficient cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular deletion of 9p sequences in non‐small cell lung cancer and malignant mesothelioma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p16 tumor suppressor gene mutations in Chinese esophageal carcinomas in Hong Kong.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of expression of the p16 gene is frequent in malignant skin tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Informative MspI polymorphism adjacent to exon 3 of the p16INK4 (MTS1) gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Absence of p16/MTS1 gene mutations in human prostate cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cooperative effects of INK4a and ras in melanoma susceptibility in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adenovirus-mediated p16/CDKN2 gene transfer suppresses glioma invasion in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multigenetic lesions in infant acute leukaemias: correlations with ALL-1 gene status
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytogenetic analysis of melanocytes from premalignant nevi and melanomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of adenovirus-mediated p16INK4A expression on cell cycle arrest are determined by endogenous p16 and Rb status in human cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MTS1 gene mutations in archival oral squamous cell carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alterations of CDKN2 (p16) in non-small cell lung cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biochemical characterization of p16INK4- and p18-containing complexes in human cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human protein p19ARF is not detected in hemopoietic human cell lines that abundantly express the alternative beta transcript of the p16INK4a/MTS1 gene.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High frequency of chromosome 9 deletion in ovarian cancer: evidence for three tumour-suppressor loci.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deletions of Interferon Genes in Acute Lymphoblastic Leukemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homozygous deletion of the alpha- and beta 1-interferon genes in human leukemia and derived cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p16 and p18 tumor suppressor genes in neuroblastoma: implications for drug resistance.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased expression of cyclin-dependent kinase inhibitor 2 (CDKN2A) gene product P16INK4A in ovarian cancer is associated with progression and unfavourable prognosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Retinoblastoma and p16 proteins in mammary carcinoma: their relationship to cyclin D1 and histopathological parameters
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of heterozygosity on chromosome 9 in human breast cancer: Association with clinical variables and genetic changes at other chromosome regions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of human tumour suppressor genes by monochromosome transfer: rapid growth-arrest response mapped to 9p21 is mediated solely by the cyclin-D-dependent kinase inhibitor gene, CDKN2A (p16INK4A).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Low frequency of p16/CDKN2 gene mutations in esophageal carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional interactions of the retinoblastoma protein with mammalian D-type cyclins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of pRb phosphorylation and cell-cycle progression by a 20-residue peptide derived from p16CDKN2/INK4A
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P16INK4A gene homozygous deletions in human acute leukaemias with alterations of chromosome 9
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prevalence of germ-line mutations in p16, p19ARF, and CDK4 in familial melanoma: analysis of a clinic-based population
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of the CDKN2A, CDKN2B and CDK4 genes in 48 Australian melanoma kindreds
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homozygous deletions within human chromosome band 9p21 in melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic and physical map of the interferon region on chromosome 9p.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of p18INK4c and its predominant association with CDK4 and CDK6 during myogenic differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A frequent polymorphism in exon 1 of the p16/CDKN2 gene.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alteration of p16 and p15 genes in common epithelial ovarian tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cumulative prognostic value of p16/CDKN2 and p53 oncoprotein expression in premalignant laryngeal lesions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular analysis of the cyclin-dependent kinase inhibitor genes p15INK4b/MTS2, p16INK4/MTS1, p18 and p19 in human cancer cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Spontaneous transformation of rat ovarian surface epithelial cells: association with cytogenetic changes and implications of repeated ovulation in the etiology of ovarian cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased Risk of Pancreatic Cancer in Melanoma-Prone Kindreds withp16INK4Mutations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Replicative senescence: the human fibroblast comes of age.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Frequent loss of the cyclin-dependent kinase-4 inhibitor gene in human gliomas.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation analysis of the p53, APC, and p16 genes in the Barrett's oesophagus, dysplasia, and adenocarcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High Frequency of Chromosome 9p Allelic Loss and CDKN2 Tumor Suppressor Gene Alterations in Squamous Cell Carcinoma of the Bladder
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CDKN2 explains part of the clinical phenotype in Dutch familial atypical multiple-mole melanoma (FAMMM) syndrome families.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homozygotes for CDKN2 (p16) germline mutation in Dutch familial melanoma kindreds
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation and characterization of p19INK4d, a p16-related inhibitor specific to CDK6 and CDK4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deletion mapping indicates that MTS1 is the target of frequent deletions at chromosome 9p21 in paediatric acute lymphoblastic leukaemias.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Germline Mutations of the CDKN2 Gene in UK Melanoma Families
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mdm2 promotes the rapid degradation of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Somatic mutations of the MTS (multiple tumor suppressor) 1/CDK4l (cyclin-dependent kinase-4 inhibitor) gene in human primary non-small cell lung carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The current situation with regard to human melanoma and genetic inferences.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Infrequent Mutation of p16INK4 in Sporadic Melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hemizygous or homozygous deletion of the chromosomal region containing the p16INK4a gene is associated with amplification of the EGF receptor gene in glioblastomas.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations and polymorphisms in the p53, p21 and p16 genes in oral carcinomas of Indian betel quid chewers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of the p16/MTS1 tumor suppressor gene causes E2F-mediated deregulation of essential enzymes of the DNA precursor metabolism.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sequence variation and chromosomal mapping of the murine Cdkn2a tumor suppressor gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prognostic importance of p15INK4B and p16INK4 gene inactivation in childhood acute lymphocytic leukemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Spontaneous and radiation-induced renal tumors in the Eker rat model of dominantly inherited cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular genetic basis of renal carcinogenesis in the Eker rat model of tuberous sclerosis (Tsc2)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p16INK4, pRB, p53 and cyclin D1 expression and hypermethylation of CDKN2 gene in thymoma and thymic carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inactivation of p16INK4 in hepatocellular carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Germline p16 mutations in familial melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-beta in cells lacking the CDK inhibitor p15
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inactivation of p16/CDKN2 and p15/MTS2 genes in different histological types and clinical stages of primary ovarian tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Highly frequent homozygous deletion of the p16 gene in esophageal cancer cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High frequency of homozygous deletions of CDK4I gene in childhood acute lymphoblastic leukaemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of cyclin-dependent kinase inhibitor genes (CDKN2A, CDKN2B, andCDKN2C) in childhood rhabdomyosarcoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Concomitant presence of p16/cyclin-dependent kinase 4 and cyclin D/cyclin-dependent kinase 4 complexes in LNCaP prostatic cancer cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abnormalities of the P16INK4A gene in thyroid cancer cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homozygous deletions of p16INK4A/MTS1 and p15INK4B/MTS2 genes in glioma cells and primary glioma tissues.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Potential role for concurrent abnormalities of the cyclin D1, p16CDKN2 and p15CDKN2B genes in certain B cell non-Hodgkin's lymphomas. Functional studies in a cell line (Granta 519).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Partial deletions of the CDKN2 and MTS2 putative tumor suppressor genes in a myxoid chondrosarcoma.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chromosome 9 related aberrations and deletions of the CDKN2 and MTS2 putative tumor suppressor genes in human chondrosarcomas.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparative analysis of Homo sapiens and Mus musculus cyclin-dependent kinase (CDK) inhibitor genes p16 (MTS1) and p15 (MTS2)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High frequency deletion of the tumour suppressor gene P16INK4a (MTS1) in human thyroid cancer cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Infrequent somatic mutation of the MTS1 gene in primary bladder carcinomas.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NMR structural characterization of the CDK inhibitor p19INK4d.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A cell cycle regulator potentially involved in genesis of many tumor types
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alterations of the p16INK4A gene in human ovarian cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular analysis of a family of cyclin-dependent kinase inhibitor genes (p15/MTS2/INK4b and p18/INK4c) in non-small cell lung cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular analysis of the cyclin-dependent kinase inhibitor family: p16(CDKN2/MTS1/INK4A), p18(INK4C) and p27(Kip1) genes in neuroblastomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential inactivation of CDKN2 and Rb protein in non-small-cell and small-cell lung cancer cell lines.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CDKN2 in HPV-positive and HPV-negative cervical-carcinoma cell lines.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of heterozygosity at 9p and 17q in human laryngeal tumors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Contribution of Chromosome 9p21‐22 Deletion to the Progression of Human Renal Cell Carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Infrequent alterations of the p16INK4A gene in liver cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Histopathology, classification, and grading of gliomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of tumorigenicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation and cancer: statistical study of retinoblastoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutational analysis of CDKN2 (CDK4I/MTS1) gene in tissues and cell lines of human prostate cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A possible subgroup of ALL with 9p-
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunohistochemical analysis of the p16INK4 cyclin-dependent kinase inhibitor in malignant mesothelioma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of p53 stability by Mdm2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations of the INK4a locus in squamous cell carcinomas of human skin.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Primary malignant lymphoma of the brain: demonstration of frequent p16 and p15 gene deletions.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the CDKN2A ( p16INK4a ) gene in microdissected sporadic primary melanomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin dependent kinase regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53, the cellular gatekeeper for growth and division
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming Growth Factor β Activates the Promoter of Cyclin-dependent Kinase Inhibitor p15 through an Sp1 Consensus Site
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Establishment, characterization and drug sensitivity of four new human soft tissue sarcoma cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cancer-associated mis-sense and deletion mutations impair p16INK4 CDK inhibitory activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of chromosome 9 deletions in transitional cell carcinoma by microsatellite assay
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human T-cell leukemia virus type 1 Tax releases cell cycle arrest induced by p16INK4a
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the cyclin-dependent kinase inhibitor p19Ink4d
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin D1 is dispensable for G1 control in retinoblastoma gene-deficient cells independently of cdk4 activity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA tumor virus oncoproteins and retinoblastoma gene mutations share the ability to relieve the cell's requirement for cyclin D1 function in G1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytogenetics of non-small cell lung cancer: analysis of consistent non-random abnormalities
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homozygous deletions and loss of expression of the CDKN2 gene occur frequently in head and neck squamous cell carcinoma cell lines but infrequently in primary tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic heterogeneity in familial malignant melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homozygous deletion frequency and expression levels of the CDKN2 gene in human sarcomas--relationship to amplification and mRNA levels of CDK4 and CCND1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of the pRb/p16/cdk4/cyclin D1 pathway in the tumorigenesis of sporadic malignant melanomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inactivation of the cyclin-dependent kinase inhibitor p15INK4b by deletion and de novo methylation with independence of p16INK4a alterations in murine primary T-cell lymphomas.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p16 (CDKN2/MTS1) Gene Deletions are Rare in Prostatic Carcinomas in the United States and Japan
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Frequent microsatellite alterations at chromosomes 9p21 and 3p14 in oral premalignant lesions and their value in cancer risk assessment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alterations of P16 (MTS1) in node-positive non-small cell lung carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypermethylation of a 5′ CpG island of p16 is a frequent event in non-Hodgkin’s lymphoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A challenge to p16 gene as a major tumor suppressor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alterations of p16/CDKN2, p53 and ras genes in oral squamous cell carcinomas and premalignant lesions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increase in radiation sensitivity of human malignant melanoma cells by expression of wild-type p16 gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ankyrin for clues about the function of p16INK4a
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Growth suppression by p16ink4 requires functional retinoblastoma protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p21waf1 can block cells at two points in the cell cycle, but does not interfere with processive DNA-replication or stress-activated kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of G1 kinase activity for cdk6, a novel cyclin D partner
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alterations of the p15, p16,and p18 genes in osteosarcoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p19INK4D Cyclin dependent kinase inhibitor gene is altered in osteosarcoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased radiosensitivity of p16 gene-deleted human glioma cells after transfection with wild-type p16 gene.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Allelotype analysis in mouse hepatocellular carcinomas; frequent homozygous deletion of mouse homolog of p16/CDKN2 gene on chromosome 4 in culture
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homozygous deletion of mouse homolog of p16/CDKN2 gene on chromosome 4 in mouse liver epithelial cells in culture
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Principles of CDK regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional and posttranscriptional regulation of exogenous human beta interferon gene in simian cells defective in interferon synthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of the cyclin‐dependent kinase inhibitors p16INK4, p15INK4B and p21Waf1/cip1 in human breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of heterozygosity on chromosome 9 andp16 (MTS1, CDKN2) gene mutations in esophageal cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A CDKN2-like polymorphism in Xiphophorus LG V is associated with UV-B-induced melanoma formation in platyfish-swordtail hybrids
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular analysis of the cyclin-dependent kinase inhibitor genes, p15, p16, p18 and p19 in the myelodysplastic syndromes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural integrity of the cyclin‐dependent kinase inhibitor genes, p15, p16 and p18 in myeloid leukaemias
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Frequent codeletion of p16/MTS1 and p15/MTS2 and genetic alterations in p16/MTS1 in pancreatic tumors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alterations of multiple tumor suppressor genes (p53 (17p13), p16INK4 (9p21), and DBM (13q14)) in B-cell chronic lymphocytic leukemia.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genomic cloning of methylthioadenosine phosphorylase: a purine metabolic enzyme deficient in multiple different cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ordering S phase and M phase in the cell cycle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation but not inactivation of the MTS1 gene is associated with primary colorectal carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deletion mapping of chromosome region 9p21-p22 surrounding the CDKN2 locus in melanoma.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Infrequent somatic alteration of p16/MTS1 in human primary superficial bladder cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations and altered expression of p16INK4 in human cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular cloning, expression pattern, and chromosomal localization of human CDKN2D/INK4d, an inhibitor of cyclin D-dependent kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Construction of a 2.8-megabase yeast artificial chromosome contig and cloning of the human methylthioadenosine phosphorylase gene from the tumor suppressor region on 9p21
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alterations of the p16 gene in head and neck cancer: frequency and association with p53, PRAD-1 and HPV
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homozygous deletions of the CDKN2/p16 gene in dural hemangiopericytomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deletion of the p16 and p15 Genes in Human Bladder Tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Leukocyte and fibroblast interferon genes are located on human chromosome 9
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homozygous deletions but no sequence mutations in coding regions of p15 or p16 in human primary bladder tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Accumulation of p16INK4a in mouse fibroblasts as a function of replicative senescence and not of retinoblastoma gene status
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Frequent inactivation of p16INK4a in oral premalignant lesions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
G1 events and regulation of cell proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular analysis of the INK4 family of genes in prostate carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Temperature-sensitive mutants of p16CDKN2 associated with familial melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Low frequency of CDKN2 mutation in endometrial carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The D-type cyclins and their role in tumorigenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Common alternative gene alterations in adult malignant astrocytomas, but not in childhood primitive neuroectodermal tumors: P 16ink4 homozygous deletions and CDK4 gene amplifications.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p16/CDKN2 andCDK4 gene mutations in sporadic melanoma development and progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparative mapping of 50 human chromosome 9 loci in the laboratory mouse
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Screening of germline mutations in the CDKN2A and CDKN2B genes in Swedish families with hereditary cutaneous melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutational analysis of the CDKN2 gene in metastases from patients with cutaneous malignant melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genes involved in cell cycle G1 checkpoint control are frequently mutated in human melanoma metastases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Compilation of somatic mutations of the CDKN2 gene in human cancers: non-random distribution of base substitutions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Redistribution of the CDK inhibitor p27 between different cyclin.CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cancer-associated mutations at the INK4a locus cancel cell cycle arrest by p16INK4a but not by the alternative reading frame protein p19ARF.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of p16 gene deletion and point mutation in breast carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transfer of p16inka/CDKN2 gene in leukaemic cell lines inhibits cell proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The multiple tumor suppressor 1/cyclin-dependent kinase inhibitor 2 gene in human central nervous system primitive neuroectodermal tumor.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations associated with familial melanoma impair p16INK4 function.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The subcellular locations of p15(Ink4b) and p27(Kip1) coordinate their inhibitory interactions with cdk4 and cdk2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential expression of p16INK4a and p16beta transcripts in B-lymphoblastoid cells from members of hereditary melanoma families without CDKN2A exon mutations.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of MTS1/CDK4 in female breast carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intragenic mutations of the p16(INK4), p15(INK4B) and p18 genes in primary non-small-cell lung cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inversely correlated expression of p16 and Rb protein in non-small cell lung cancers: an immunohistochemical study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alterations of tumor suppressor genes and the H-ras oncogene in oral squamous cell carcinoma.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of heterozygosity on the short arm of chromosome 9 without p16 gene mutation in gastric carcinomas.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming growth factor beta stabilizes p15INK4B protein, increases p15INK4B-cdk4 complexes, and inhibits cyclin D1-cdk4 association in human mammary epithelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adenovirally transferred p16INK4/CDKN2 and p53 genes cooperate to induce apoptotic tumor cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of Cip/Kip and Ink4 cyclin dependent kinase inhibitors by interferon-alpha in hematopoietic cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Infrequent alterations of the p15, p16, CDK4 and cyclin D1 genes in non-astrocytic human brain tumors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chromosome-9 loss detected by fluorescence in situ hybridization in bladder cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Infrequent methylation of CDKN2A(MTS1/p16) and rare mutation of both CDKN2A and CDKN2B(MTS2/p15) in primary astrocytic tumours
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of heterozygosity on chromosome 9q21 (p16 gene) uncommon in soft-tissue sarcomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CDKN2 gene deletion is not found in chronic lymphoid leukaemias of B- and T-cell origin but is frequent in acute lymphoblastic leukaemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sporadic CDKN2 (MTS1/p16ink4) gene alterations in human ovarian tumours
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression and regulation of G1 cell-cycle inhibitors (p16INK4A, p15INK4B, p18INK4C, p19INK4D) in human acute myeloid leukemia and normal myeloid cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of the cyclin-dependent kinase-4 inhibitor (CDKN2) gene in the pathogenesis of lymphoid blast crisis of chronic myelogenous leukaemia.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of ras-induced proliferation and cellular transformation by p16INK4.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of the INK4a locus in tumor suppression and cell mortality.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role for both RB and p53 in the regulation of human cellular senescence
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
G1 phase progression: cycling on cue
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cancer cell cycles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibitors of mammalian G1 cyclin-dependent kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p16 overexpression: a potential early indicator of transformation in ovarian carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of heterozygosity at 9p21 loci and mutations of the MTS1 and MTS2 genes in human lung cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two tracks but one race? Cancer genetics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of the novel cyclin-dependent kinase 4 and 6 inhibitor gene p18 in lymphoma and leukemia cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homozygous loss of the MTS1/p16 and MTS2/p15 genes in lymphoma and lymphoblastic leukaemia cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutational analysis of the p15 and p16 genes in acute leukaemias
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Replicative senescence: implications for in vivo aging and tumor suppression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The 5'-flanking region of the E1 alpha form of the murine p16INK4a (MTS1) gene.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of the cyclin‐dependent kinase inhibitor p16 during the ongoing cell cycle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prevalence of p16 and CDK4 germline mutations in 48 melanoma-prone families in France. The French Familial Melanoma Study Group [published erratum appears in Hum Mol Genet 1998 May;7(5):941]
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of cyclin-dependent kinase inhibitor genes and chromosome 9 karyotypic abnormalities in human bladder cancer cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of growth in vitro and tumorigenicity in vivo of human carcinoma cell lines by transfected p16INK4.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P16 gene in uncultured tumours
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The 9p21 region in bladder cancer cell lines: large homozygous deletion inactivate the CDKN2, CDKN2B and MTAP genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Origins of G1 arrest in senescent human fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CDKN2A mutation in a non-FAMMM kindred with cancers at multiple sites results in a functionally abnormal protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intragenic mutations of CDKN2B and CDKN2A in primary human esophageal cancers.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Frequent aberrant methylation of p16INK4a in primary rat lung tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Assignment of 12 loci to rat chromosome 5: evidence that this chromosome is homologous to mouse chromosome 4 and to human chromosomes 9 and 1 (1p arm)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p16/CDKN2 gene and p53 gene alterations in Japanese non-smoking female lung adenocarcinoma.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of expression of thep16INK4/CDKN2 gene in cutaneous malignant melanoma correlates with tumor cell proliferation and invasive stage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homozygous deletions of p16(INK4) occur frequently in bilharziasis-associated bladder cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p16 mutations/deletions are not frequent events in prostate cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple types of aberrations in the p16 (INK4a) and the p15(INK4b) genes in 30 esophageal squamous-cell-carcinoma cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of the p16INK4A, p15INK4B and p18INK4C genes in multiple myeloma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deletion and transfection analysis of the p15/MTS2 gene in malignant gliomas.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Localization of the interferon-alpha gene cluster to rat chromosome bands 5q31----q33 by fluorescence in situ hybridization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor suppressor p16INK4A: structural characterization of wild-type and mutant proteins by NMR and circular dichroism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chromosomal localization of human leukocyte, fibroblast, and immune interferon genes by means of in situ hybridization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Infrequent CDKN2 mutation in human differentiated thyroid cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The CDKN2 gene alterations in various types of adult T-cell leukaemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MTS1/CDKN2 gene mutations are rare in primary human astrocytomas with allelic loss of chromosome 9p
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of senescence in human malignant glioma cells by p16INK4A.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct roles for cyclin-dependent kinases in cell cycle control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the CDK4/6 inhibitory protein p18INK4c provides insights into ankyrin-like repeat structure/function and tumor-derived p16INK4 mutations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prognostic implications of cyclins (D1, E, A), cyclin-dependent kinases (CDK2, CDK4) and tumor-suppressor genes (pRB, p16INK4A) in childhood acute lymphoblastic leukemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homozygous deletions of the MTS1 gene are rare in non-astrocytic brain tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations of the CDKN2/p16INK4 gene in Australian melanoma kindreds
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Localization of a putative tumor suppressor gene by using homozygous deletions in melanomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The retinoblastoma protein and cell cycle control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A Familial Syndrome of Pancreatic Cancer and Melanoma with a Mutation in theCDKN2Tumor-Suppressor Gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p16 (CDKN2) is a major deletion target at 9p21 in bladder cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Allelotyping of butadiene-induced lung and mammary adenocarcinomas of B6C3F1 mice: frequent losses of heterozygosity in regions homologous to human tumor-suppressor genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential CDK-inhibitor gene expression in aging human diploid fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intragenic homozygous deletions of MTS1 gene in gastric cancer in Taiwan.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Growth arrest and suppression of tumorigenicity of bladder-carcinoma cell lines induced by the P16/CDKN2 (p16INK4A, MTS1) gene and other loci on human chromosome 9
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lack of p16/CDKN2 alterations in thyroid carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of p16INK4aand Its Interaction with CDK4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Familial tumor syndrome associated with a germline nonfunctional p16INK4a allele
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MTS1/CDK4I is altered in cell lines derived from primary and metastatic oral squamous cell carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Infrequent mutations of p16INK4A and p15INK4B genes in human pituitary adenomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Codeletion of the genes for p16INK4, methylthioadenosine phosphorylase, interferon-alpha1, interferon-beta1, and other 9p21 markers in human malignant cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A comparative study of glioma cell lines for p16, p15, p53 and p21 gene alterations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genomic DNA and messenger RNA expression alterations of the CDKN2B and CDKN2 genes in esophageal squamous carcinoma cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-419X%2898%2900017-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0304-419X(98)00017-1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9823374
retrieved
27 May 2018
reference URL
http://europepmc.org/abstract/MED/9823374
PubMed publication ID
9823374
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9823374
retrieved
27 May 2018
reference URL
http://europepmc.org/abstract/MED/9823374
ResearchGate publication ID
13464081
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