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English
Mutations in serines 15 and 20 of human p53 impair its apoptotic activity.
scientific article published in May 1999
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10359526
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10359526%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
title
Mutations in serines 15 and 20 of human p53 impair its apoptotic activity
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10359526
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10359526%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
main subject
apoptotic process
0 references
author
Peter Howley
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10359526
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10359526%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
author name string
Unger T
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10359526
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10359526%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
Sionov RV
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10359526
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10359526%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
Moallem E
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10359526
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10359526%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
Yee CL
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10359526
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10359526%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
Oren M
series ordinal
6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10359526
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10359526%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
Haupt Y
series ordinal
7
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10359526
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10359526%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
language of work or name
English
0 references
publication date
1 May 1999
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10359526
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10359526%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
published in
Oncogene
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10359526
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10359526%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
volume
18
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10359526
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10359526%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
issue
21
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10359526
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10359526%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
page(s)
3205-3212
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10359526
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10359526%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
cites work
Enhanced phosphorylation of p53 by ATM in response to DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 in signaling checkpoint arrest or apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional activation by p53 correlates with suppression of growth but not transformation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Features of apoptotic cells measured by flow cytometry
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A transcriptionally active DNA-binding site for human p53 protein complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 in growth control and neoplasia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of p53 at the casein kinase II site selectively regulates p53-dependent transcriptional repression but not transactivation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation of phosphoserine 389 affects p53 function in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mdm2 promotes the rapid degradation of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of apoptosis in HeLa cells by trans-activation-deficient p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of the specific DNA binding function of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 is phosphorylated by CDK7-cyclin H in a p36MAT1-dependent manner
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of p53 stability by Mdm2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53, the cellular gatekeeper for growth and division
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of IkappaBalpha in the C-terminal PEST domain by casein kinase II affects intrinsic protein stability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The CDK7-cycH-p36 complex of transcription factor IIH phosphorylates p53, enhancing its sequence-specific DNA binding activity in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human TAFII31 protein is a transcriptional coactivator of the p53 protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multisite phosphorylation and the integration of stress signals at p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p53 tumour suppressor protein is phosphorylated at serine 389 by casein kinase II.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 Phosphorylation: biochemical and functional consequences
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation of the casein kinase II phosphorylation site abolishes the anti-proliferative activity of p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel form of Epstein-Barr virus latency in normal B cells in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mdm-2: "big brother" of p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wild-type p53 negatively regulates the expression of a microtubule-associated protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p53-binding protein 53BP2 also interacts with Bc12 and impedes cell cycle progression at G2/M
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A model for p53-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The insulin-like growth factor I receptor as a physiologically relevant target of p53 in apoptosis caused by interleukin-3 withdrawal.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signaling to p53: breaking the MDM2-p53 circuit
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA damage induces phosphorylation of the amino terminus of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
How phosphorylation regulates the activity of p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of the sequence-specific DNA binding function of p53 by protein kinase C and protein phosphatases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transactivation by NF-IL6/LAP is enhanced by phosphorylation of its activation domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional domains of wild-type and mutant p53 proteins involved in transcriptional regulation, transdominant inhibition, and transformation suppression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis by p53: mechanisms, regulation, and clinical implications
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased and altered DNA binding of human p53 by S and G2/M but not Gl cyclin-dependent kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clues in the p53 murder mystery
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202656
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.ONC.1202656
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10359526
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10359526%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
PubMed publication ID
10359526
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10359526
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10359526%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
ResearchGate publication ID
12938501
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