(Q53376168)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16354907%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

title

IgG-assisted age-dependent clearance of Alzheimer's amyloid beta peptide by the blood-brain barrier neonatal Fc receptor (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16354907%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

0 references

1 reference

David M Holtzman

2 references

PubMed publication ID

16354907

13 May 2018

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16354907%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Rashid Deane

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16354907%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Abhay Sagare

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16354907%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Katie Hamm

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16354907%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Margaret Parisi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16354907%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Barbra LaRue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16354907%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Huang Guo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16354907%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Zhenhua Wu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16354907%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Berislav V Zlokovic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16354907%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

language of work or name

English

0 references

publication date

1 December 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16354907%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

published in

Journal of Neuroscience

1 reference

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10 January 2020

volume

1 reference

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10 January 2020

issue

1 reference

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10 January 2020

page(s)

11495-11503

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16354907%20AND%20SRC:MED&resulttype=core&format=json

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

10 January 2020

cites work

1 reference

12 December 2020

Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

1 reference

12 December 2020

Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier

1 reference

12 December 2020

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

1 reference

12 December 2020

A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

1 reference

12 December 2020

Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease.

1 reference

12 December 2020

Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy

1 reference

12 December 2020

1 reference

12 December 2020

Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease

1 reference

12 December 2020

Enzymatic iodination of polypeptides with 125I to high specific activity

1 reference

12 December 2020

Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice

1 reference

12 December 2020

Reduced effectiveness of Abeta1-42 immunization in APP transgenic mice with significant amyloid deposition

1 reference

12 December 2020

Brain to plasma amyloid-beta efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease

1 reference

12 December 2020

Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model

1 reference

12 December 2020

Expression of the neonatal Fc receptor (FcRn) at the blood-brain barrier

1 reference

12 December 2020

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

12 December 2020

Antibodies to beta-amyloid decrease the blood-to-brain transfer of beta-amyloid peptide

1 reference

12 December 2020

Non-Fc-mediated mechanisms are involved in clearance of amyloid-beta in vivo by immunotherapy.

1 reference

12 December 2020

Novel therapeutic approach for the treatment of Alzheimer's disease by peripheral administration of agents with an affinity to beta-amyloid.

1 reference

12 December 2020

Passage of amyloid beta protein antibody across the blood-brain barrier in a mouse model of Alzheimer's disease

1 reference

12 December 2020

Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report.

1 reference

12 December 2020

The MHC class I-like IgG receptor controls perinatal IgG transport, IgG homeostasis, and fate of IgG-Fc-coupled drugs

1 reference

12 December 2020

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

1 reference

12 December 2020

Intracranially Administered Anti-Αβ Antibodies Reduce β-Amyloid Deposition by Mechanisms Both Independent of and Associated with Microglial Activation

1 reference

12 December 2020

Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease

1 reference

12 December 2020

RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain

1 reference

12 December 2020

Investigation of IgG receptors expressed on the surface of human placental endothelial cells.

1 reference

12 December 2020

Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization

1 reference

12 December 2020

Evidence for peripheral clearance of cerebral Abeta protein following chronic, active Abeta immunization in PSAPP mice

1 reference

12 December 2020

Amyloid-beta immunization effectively reduces amyloid deposition in FcRgamma-/- knock-out mice

1 reference

12 December 2020

Phagocytosis and deposition of vascular beta-amyloid in rat brains injected with Alzheimer beta-amyloid

1 reference

12 December 2020

Efflux of human and mouse amyloid β proteins 1–40 and 1–42 from brain: impairment in a mouse model of alzheimer's disease

1 reference

12 December 2020

In VivoAssessment of Brain Interstitial Fluid with Microdialysis Reveals Plaque-Associated Changes in Amyloid-β Metabolism and Half-Life

1 reference

12 December 2020

A simple method for isolation and characterization of mouse brain microvascular endothelial cells

1 reference

12 December 2020

Clearing amyloid through the blood-brain barrier

1 reference

12 December 2020

Human neonatal Fc receptor mediates transport of IgG into luminal secretions for delivery of antigens to mucosal dendritic cells.

1 reference

12 December 2020

Exocytosis of IgG as mediated by the receptor, FcRn: an analysis at the single-molecule level

1 reference

12 December 2020

Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome

1 reference

12 December 2020

LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms.

1 reference

12 December 2020

Method for measurement of the blood-brain barrier permeability in the perfused mouse brain: application to amyloid-beta peptide in wild type and Alzheimer's Tg2576 mice

1 reference

12 December 2020

Clearance of Alzheimer's Abeta peptide: the many roads to perdition.

1 reference

12 December 2020

Alzheimer's beta-peptide oligomer formation at physiologic concentrations

1 reference

12 December 2020

Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo

1 reference

12 December 2020

Effects of a behaviorally active antibody on the brain uptake and clearance of amyloid beta proteins

1 reference

12 December 2020

Quantitative measurement of changes in amyloid-beta(40) in the rat brain and cerebrospinal fluid following treatment with the gamma-secretase inhibitor LY-411575 [N2-[(2S)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl]-N1-[(7S)-5-methyl-6-oxo-6,7-dihydro

1 reference

12 December 2020

Neurovascular mechanisms of Alzheimer's neurodegeneration

1 reference

12 December 2020

A saturable mechanism for transport of immunoglobulin G across the blood-brain barrier of the guinea pig

1 reference

12 December 2020

Immunoneurology: a serum protein afferent limb to the CNS.

1 reference

12 December 2020

Avenues for entry of peripherally administered protein to the central nervous system in mouse, rat, and squirrel monkey

1 reference

12 December 2020

Differential expression of Na,K-ATPase alpha and beta subunit isoforms at the blood-brain barrier and the choroid plexus.

1 reference

12 December 2020

Serum proteins bypass the blood-brain fluid barriers for extracellular entry to the central nervous system

1 reference

12 December 2020

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

12 December 2020

Isoform-specific effects of apolipoproteins E2, E3, and E4 on cerebral capillary sequestration and blood-brain barrier transport of circulating Alzheimer's amyloid beta.

1 reference

12 December 2020

Slow degradation of aggregates of the Alzheimer's disease amyloid beta-protein by microglial cells.

1 reference

12 December 2020

Functional expression of the MHC class I-related receptor, FcRn, in endothelial cells of mice.

1 reference

12 December 2020

10.1523/JNEUROSCI.3697-05.2005

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16354907%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16354907%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

PubMed publication ID

16354907

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16354907%20AND%20SRC:MED&resulttype=core&format=json