(Q52603828)

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FDA Approval Summary: Tocilizumab for Treatment of Chimeric Antigen Receptor T Cell-Induced Severe or Life-Threatening Cytokine Release Syndrome.

scientific article published on 5 April 2018

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29622697%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

FDA Approval Summary: Tocilizumab for Treatment of Chimeric Antigen Receptor T Cell-Induced Severe or Life-Threatening Cytokine Release Syndrome (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29622697%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

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Robert Q Le

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29622697%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Liang Li

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29622697%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Weishi Yuan

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29622697%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Stacy S Shord

4

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Europe PubMed Central

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22 March 2020

Lei Nie

5

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22 March 2020

Bahru A Habtemariam

6

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22 March 2020

Donna Przepiorka

7

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29622697%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Ann T Farrell

8

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Europe PubMed Central

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22 March 2020

Richard Pazdur

9

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22 March 2020

publication date

5 April 2018

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22 March 2020

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29622697%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

23

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22 March 2020

8

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22 March 2020

943-947

1 reference

Europe PubMed Central

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22 March 2020

Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2

1 reference

https://pubmed.ncbi.nlm.nih.gov/29622697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/29622697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thorough QT/QTc study of tocilizumab after single-dose administration at therapeutic and supratherapeutic doses in healthy subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/29622697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29622697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/29622697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chimeric antigen receptor-modified T cells for acute lymphoid leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/29622697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/29622697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Current concepts in the diagnosis and management of cytokine release syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/29622697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/29622697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chimeric antigen receptor T cells for sustained remissions in leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/29622697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/29622697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tocilizumab-induced neutropenia in rheumatoid arthritis patients with previous history of neutropenia: case series and review of literature

1 reference

https://pubmed.ncbi.nlm.nih.gov/29622697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/29622697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of Predictive Biomarkers for Cytokine Release Syndrome after Chimeric Antigen Receptor T-cell Therapy for Acute Lymphoblastic Leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/29622697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toxicities of chimeric antigen receptor T cells: recognition and management

1 reference

https://pubmed.ncbi.nlm.nih.gov/29622697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine Release Syndrome After Chimeric Antigen Receptor T Cell Therapy for Acute Lymphoblastic Leukemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29622697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine release syndrome with novel therapeutics for acute lymphoblastic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/29622697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible Compartmental Cytokine Release Syndrome in a Patient With Recurrent Ovarian Cancer After Treatment With Mesothelin-targeted CAR-T Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29622697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1634/THEONCOLOGIST.2018-0028

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29622697%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29622697%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29622697%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

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