(Q52542455)

3 May 2018

title

Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice. (English)

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3 May 2018

Nijmegen breakage syndrome

main subject

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Zhu J

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3 May 2018

Petersen S

series ordinal

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3 May 2018

Tessarollo L

series ordinal

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3 May 2018

Nussenzweig A

series ordinal

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3 May 2018

language of work or name

English

0 references

publication date

1 January 2001

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3 May 2018

published in

Current Biology

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3 May 2018

volume

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3 May 2018

issue

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3 May 2018

page(s)

105-109

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3 May 2018

Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome

cites work

1 reference

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7 January 2021

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

1 reference

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7 January 2021

An increased risk for malignant neoplasms in heterozygotes for a syndrome of microcephaly, normal intelligence, growth retardation, remarkable facies, immunodeficiency and chromosomal instability.

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7 January 2021

Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2801%2900019-7

7 January 2021

A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53

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https://api.crossref.org/works/10.1016%2FS0960-9822%2801%2900019-7

7 January 2021

The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse

1 reference

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7 January 2021

Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2801%2900019-7

7 January 2021

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

1 reference

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7 January 2021

DNA double strand break repair in mammalian cells

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https://api.crossref.org/works/10.1016%2FS0960-9822%2801%2900019-7

7 January 2021

DNA repair: The Nijmegen breakage syndrome protein

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7 January 2021

In situ visualization of DNA double-strand break repair in human fibroblasts

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7 January 2021

Response to RAG-mediated VDJ cleavage by NBS1 and gamma-H2AX

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7 January 2021

Radioresistant DNA synthesis and human genetic diseases

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7 January 2021

Retroviral expression of the NBS1 gene in cultured Nijmegen breakage syndrome cells restores normal radiation sensitivity and nuclear focus formation

1 reference

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7 January 2021

The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

1 reference

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7 January 2021

Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells

1 reference

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7 January 2021

The Mre11-Rad50-Xrs2 protein complex facilitates homologous recombination-based double-strand break repair in Saccharomyces cerevisiae

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7 January 2021

Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells

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7 January 2021

Polymerase eta deficiency in the xeroderma pigmentosum variant uncovers an overlap between the S phase checkpoint and double-strand break repair

1 reference

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7 January 2021

Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2801%2900019-7

7 January 2021

A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2801%2900019-7

7 January 2021

10.1016/S0960-9822(01)00019-7

Identifiers

DOI

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3 May 2018

1 reference

3 May 2018