(Q51790795)

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3 January 2020

title

Neurodegeneration and motor dysfunction in a conditional model of Parkinson's disease (English)

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3 January 2020

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3 January 2020

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3 January 2020

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3 January 2020

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3 January 2020

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3 January 2020

Silke Nuber

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3 January 2020

Olaf Riess

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Elisabeth Petrasch-Parwez

3 January 2020

object named as

Elisabeth Petrasch-Parwez

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3 January 2020

Jürgen Winkler

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3 January 2020

Jana Boy

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3 January 2020

Peter Teismann

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3 January 2020

Ina Schmitt

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3 January 2020

Thorsten Schmidt

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3 January 2020

Melanie Kuhn

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3 January 2020

Bernd J Pichler

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3 January 2020

Gerald Reischl

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3 January 2020

Antje Bornemann

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3 January 2020

Wilfried Kuhn

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3 January 2020

Frank Zimmermann

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3 January 2020

Antonio Servadio

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3 January 2020

Manuela Neumann

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3 January 2020

language of work or name

English

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publication date

1 March 2008

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3 January 2020

published in

Journal of Neuroscience

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3 January 2020

volume

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3 January 2020

issue

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3 January 2020

page(s)

2471-2484

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describes a project that uses

3 January 2020

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6671187/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Axon pathology in Parkinson's disease and Lewy body dementia hippocampus contains alpha-, beta-, and gamma-synuclein

1 reference

12 December 2020

Nerve growth factor (NGF) augments cortical and hippocampal cholinergic functioning after p75NGF receptor-mediated deafferentation but impairs inhibitory avoidance and induces fear-related behaviors.

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12 December 2020

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

1 reference

12 December 2020

Synthesis, biodistribution, and primate imaging of fluorine-18 labeled 2beta-carbo-1'-fluoro-2-propoxy-3beta-(4-chlorophenyl)tr opanes. Ligands for the imaging of dopamine transporters by positron emission tomography

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12 December 2020

Detection of the effects of dopamine receptor supersensitivity using pharmacological MRI and correlations with PET.

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12 December 2020

Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

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12 December 2020

Alpha-synuclein cortical Lewy bodies correlate with dementia in Parkinson's disease

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12 December 2020

Striatal responses to partial dopaminergic lesion: evidence for compensatory sprouting

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12 December 2020

Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease

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12 December 2020

Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha -synuclein in human and transgenic mouse brain

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12 December 2020

Graphical analysis of PET data applied to reversible and irreversible tracers

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12 December 2020

Gender differences in neurotoxicity of the nigrostriatal dopaminergic system: implications for Parkinson's disease.

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12 December 2020

A new mathematical model for relative quantification in real-time RT-PCR

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12 December 2020

Lack of nigral pathology in transgenic mice expressing human alpha-synuclein driven by the tyrosine hydroxylase promoter

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12 December 2020

The status of dopamine nerve terminals in Parkinson's disease and essential tremor: a PET study with the tracer [11-C]FE-CIT.

1 reference

12 December 2020

Selective insolubility of alpha-synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model

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12 December 2020

Impaired retention of spatial memory after transection of longitudinally oriented axons of hippocampal CA3 pyramidal cells

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12 December 2020

Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice

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12 December 2020

Central mechanisms of motor skill learning

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12 December 2020

Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein

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12 December 2020

Differential neuropathological alterations in transgenic mice expressing alpha-synuclein from the platelet-derived growth factor and Thy-1 promoters

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12 December 2020

Neuronal replacement from endogenous precursors in the adult brain after stroke

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12 December 2020

Regeneration of hippocampal pyramidal neurons after ischemic brain injury by recruitment of endogenous neural progenitors

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12 December 2020

Golgi fragmentation occurs in the cells with prefibrillar alpha-synuclein aggregates and precedes the formation of fibrillar inclusion

1 reference

12 December 2020

Evidence for neurogenesis in the adult mammalian substantia nigra

1 reference

12 December 2020

Molecular mechanisms contributing to long-lasting synaptic plasticity at the temporoammonic-CA1 synapse

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12 December 2020

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

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12 December 2020

Mapping of brain function after MPTP-induced neurotoxicity in a primate Parkinson's disease model.

1 reference

12 December 2020

Transgenic mice expressing mutant A53T human alpha-synuclein show neuronal dysfunction in the absence of aggregate formation.

1 reference

12 December 2020

alpha-Synuclein locus triplication causes Parkinson's disease

1 reference

12 December 2020

Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotective

1 reference

12 December 2020

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

1 reference

12 December 2020

Enhanced substantia nigra mitochondrial pathology in human alpha-synuclein transgenic mice after treatment with MPTP.

1 reference

12 December 2020

Short and long-term motor skill learning in an accelerated rotarod training paradigm.

1 reference

12 December 2020

Search strategies used by APP transgenic mice during navigation in the Morris water maze

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12 December 2020

A 100% increase of dopaminergic cells in the olfactory bulb may explain hyposmia in Parkinson's disease

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12 December 2020

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

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12 December 2020

Stages in the development of Parkinson's disease-related pathology

1 reference

12 December 2020

Hippocampal and prefrontal atrophy in patients with early non-demented Parkinson's disease is related to cognitive impairment

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12 December 2020

Alpha-synuclein locus duplication as a cause of familial Parkinson's disease

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12 December 2020

An application of a new planar positron imaging system (PPIS) in a small animal: MPTP-induced parkinsonism in mouse

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12 December 2020

Human Wild-Type α-Synuclein Impairs Neurogenesis

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12 December 2020

Proteasome inhibitors protect against degeneration of nigral dopaminergic neurons in hemiparkinsonian rats.

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12 December 2020

Striatal deafferentation increases dopaminergic neurogenesis in the adult olfactory bulb

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12 December 2020

Correlation between quantitative imaging and behavior in unilaterally 6-OHDA-lesioned rats

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12 December 2020

Toxin-induced models of Parkinson's disease

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12 December 2020

Non-invasive imaging of neuropathology in a rat model of alpha-synuclein overexpression

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12 December 2020

Pharmacological promotion of inclusion formation: a therapeutic approach for Huntington's and Parkinson's diseases

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12 December 2020

Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120): implications for Lewy body disorders.

1 reference

12 December 2020

Comparison of [18F]FDOPA, [18F]FMT and [18F]FECNT for imaging dopaminergic neurotransmission in mice

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12 December 2020

Induction of autophagy in axonal dystrophy and degeneration

1 reference

12 December 2020

Influence of different promoters on the expression pattern of mutated human alpha-synuclein in transgenic mice.

1 reference

12 December 2020

Bergmann glia expression of polyglutamine-expanded ataxin-7 produces neurodegeneration by impairing glutamate transport

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12 December 2020

Compensations after lesions of central dopaminergic neurons: some clinical and basic implications

1 reference

12 December 2020

Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein.

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12 December 2020

Osteopontin is elevated in Parkinson's disease and its absence leads to reduced neurodegeneration in the MPTP model

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12 December 2020

Cellular and subcellular localization of Huntingtin [corrected] aggregates in the brain of a rat transgenic for Huntington disease

1 reference

12 December 2020

Olfactory dysfunction in parkinsonism: A general deficit unrelated to neurologic signs, disease stage, or disease duration

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12 December 2020

Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations

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12 December 2020

Transcriptional activation by tetracyclines in mammalian cells

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12 December 2020

Pharmacokinetics and in vivo specificity of [11C]dl-threo-methylphenidate for the presynaptic dopaminergic neuron

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12 December 2020

New stereological methods for counting neurons

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12 December 2020

Control of memory formation through regulated expression of a CaMKII transgene

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12 December 2020

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

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12 December 2020

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

1 reference

12 December 2020

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

1 reference

12 December 2020

Compensatory mechanisms in experimental and human parkinsonism: towards a dynamic approach

1 reference

12 December 2020

Hippocampal atrophy is related to impaired memory, but not frontal functions in non-demented Parkinson's disease patients

1 reference

12 December 2020

Doxycycline control of prion protein transgene expression modulates prion disease in mice

1 reference

12 December 2020

10.1523/JNEUROSCI.3040-07.2008

Identifiers

DOI

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3 January 2020

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3 January 2020

PubMed publication ID

18322092

1 reference

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