(Q51109313)

30 March 2018

title

Insight into the activity of SARS main protease: Molecular dynamics study of dimeric and monomeric form of enzyme (English)

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30 March 2018

3C-like proteinase [SARS-Cov]

main subject

SARS-CoV-1

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author name string

Kewen Zheng

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30 March 2018

Guozheng Ma

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30 March 2018

Jinming Zhou

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30 March 2018

Min Zen

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30 March 2018

Wenna Zhao

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30 March 2018

Yongjun Jiang

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30 March 2018

Qingsen Yu

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30 March 2018

Jialiang Feng

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30 March 2018

language of work or name

English

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publication date

1 February 2007

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30 March 2018

published in

Proteins

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30 March 2018

volume

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30 March 2018

issue

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30 March 2018

page(s)

467-479

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30 March 2018

Virus-encoded proteinases and proteolytic processing in the Nidovirales.

cites work

1 reference

https://api.crossref.org/works/10.1002%2FPROT.21160

Virtual screening for SARS-CoV protease based on KZ7088 pharmacophore points

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.21160

Molecular dynamics simulations of various coronavirus main proteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.21160

Mutational analysis of the active centre of coronavirus 3C-like proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.21160

Severe acute respiratory syndrome coronavirus 3C-like proteinase N terminus is indispensable for proteolytic activity but not for enzyme dimerization. Biochemical and thermodynamic investigation in conjunction with molecular dynamics simulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.21160

Biosynthesis, Purification, and Substrate Specificity of Severe Acute Respiratory Syndrome Coronavirus 3C-like Proteinase

21 January 2018

1 reference

12 December 2020

Biosynthesis, purification, and characterization of the human coronavirus 229E 3C-like proteinase.

1 reference

12 December 2020

Dissection study on the severe acute respiratory syndrome 3C-like protease reveals the critical role of the extra domain in dimerization of the enzyme: defining the extra domain as a new target for design of highly specific protease inhibitors

1 reference

12 December 2020

Identification of novel inhibitors of the SARS coronavirus main protease 3CLpro.

1 reference

12 December 2020

The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor

1 reference

12 December 2020

Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha-helical domain

1 reference

12 December 2020

Evaluation of metal-conjugated compounds as inhibitors of 3CL protease of SARS-CoV.

1 reference

12 December 2020

The Genome sequence of the SARS-associated coronavirus

1 reference

12 December 2020

3C-like proteinase from SARS coronavirus catalyzes substrate hydrolysis by a general base mechanism

1 reference

12 December 2020

Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome.

1 reference

12 December 2020

Exploring the binding mechanism of the main proteinase in SARS-associated coronavirus and its implication to anti-SARS drug design

1 reference

12 December 2020

Three-dimensional model of a substrate-bound SARS chymotrypsin-like cysteine proteinase predicted by multiple molecular dynamics simulations: catalytic efficiency regulated by substrate binding

1 reference

12 December 2020

A novel coronavirus and SARS

1 reference

12 December 2020

Small molecules targeting severe acute respiratory syndrome human coronavirus

1 reference

12 December 2020

Coronavirus 3CLpro proteinase cleavage sites: possible relevance to SARS virus pathology

1 reference

12 December 2020

Quaternary structure of the severe acute respiratory syndrome (SARS) coronavirus main protease

1 reference

12 December 2020

Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs

1 reference

12 December 2020

Characterization of a novel coronavirus associated with severe acute respiratory syndrome

1 reference

12 December 2020

Synthesis and evaluation of keto-glutamine analogues as potent inhibitors of severe acute respiratory syndrome 3CLpro

1 reference

12 December 2020

Identifiers

DOI

10.1002/PROT.21160

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30 March 2018

PMC publication ID

7167853

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30 March 2018