(Q51094782)

29 March 2018

title

Requirement for the thymus in alphabeta T lymphocyte lineage commitment. (English)

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29 March 2018

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Carlyle JR

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29 March 2018

Zúñiga-Pflücker JC

series ordinal

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29 March 2018

language of work or name

English

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publication date

1 August 1998

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29 March 2018

published in

Immunity

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29 March 2018

volume

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29 March 2018

issue

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29 March 2018

page(s)

187-197

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29 March 2018

Limited development capacity of the earliest embryonic murine thymus

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Identification of a novel developmental stage marking lineage commitment of progenitor thymocytes

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The Ikaros gene is required for the development of all lymphoid lineages

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Isolation of the most immature population of murine fetal thymocytes that includes progenitors capable of generating T, B, and myeloid cells

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Pro-T cells in fetal thymus express c-kit and RAG-2 but do not rearrange the gene encoding the T cell receptor beta chain

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Transcription and demethylation of TCR beta gene initiate prior to the gene rearrangement in c-kit+ thymocytes with CD3 expression: evidence of T cell commitment in the thymus.

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7 January 2021

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7 January 2021

Early T lymphocyte progenitors

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7 January 2021

Abnormal development of intestinal intraepithelial lymphocytes and peripheral natural killer cells in mice lacking the IL-2 receptor beta chain

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7 January 2021

Development and characterization of v-myc/v-raf-transformed murine fetal thymocyte cell lines

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Natural killer cell development is blocked in the context of aberrant T lymphocyte ontogeny

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Generation of lytic natural killer 1.1+, Ly-49- cells from multipotential murine bone marrow progenitors in a stroma-free culture: definition of cytokine requirements and developmental intermediates

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7 January 2021

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7 January 2021

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7 January 2021

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Identifiers

DOI

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29 March 2018

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29 March 2018