(Q51029020)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14973251%20AND%20SRC:MED&resulttype=core&format=json

23 November 2019

title

Tumor necrosis factor death receptor signaling cascade is required for amyloid-beta protein-induced neuron death (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14973251%20AND%20SRC:MED&resulttype=core&format=json

23 November 2019

Harald Hampel

1 reference

PubMed publication ID

27 March 2018

Rena Li

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14973251%20AND%20SRC:MED&resulttype=core&format=json

23 November 2019

Libang Yang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14973251%20AND%20SRC:MED&resulttype=core&format=json

23 November 2019

Kristina Lindholm

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14973251%20AND%20SRC:MED&resulttype=core&format=json

23 November 2019

Yoshihiro Konishi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14973251%20AND%20SRC:MED&resulttype=core&format=json

23 November 2019

Xu Yue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14973251%20AND%20SRC:MED&resulttype=core&format=json

23 November 2019

Dai Zhang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14973251%20AND%20SRC:MED&resulttype=core&format=json

23 November 2019

Yong Shen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14973251%20AND%20SRC:MED&resulttype=core&format=json

23 November 2019

Harald Hampel

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14973251%20AND%20SRC:MED&resulttype=core&format=json

23 November 2019

language of work or name

English

0 references

publication date

1 February 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14973251%20AND%20SRC:MED&resulttype=core&format=json

23 November 2019

published in

Journal of Neuroscience

1 reference

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23 November 2019

volume

1 reference

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23 November 2019

issue

1 reference

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23 November 2019

page(s)

1760-1771

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14973251%20AND%20SRC:MED&resulttype=core&format=json

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

23 November 2019

cites work

1 reference

12 December 2020

NF-kappaB is activated and promotes cell death in focal cerebral ischemia

1 reference

12 December 2020

Inhibition of NF-kappaB potentiates amyloid beta-mediated neuronal apoptosis

1 reference

12 December 2020

Higher avidity binding of apolipoprotein (E-AII) complex than of apolipoprotein E monomer to beta-amyloid

1 reference

12 December 2020

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

1 reference

12 December 2020

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

1 reference

12 December 2020

Fibrillar Alzheimer's amyloid peptide Abeta(1-42) stimulates low density lipoprotein binding and cell association, free radical production and cell cytotoxicity in PC12 cells.

1 reference

12 December 2020

Caspase-2 mediates neuronal cell death induced by beta-amyloid

1 reference

12 December 2020

beta-Amyloid(1-42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology

1 reference

12 December 2020

Amyloid beta interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease.

1 reference

12 December 2020

Calcium signaling in the ER: its role in neuronal plasticity and neurodegenerative disorders

1 reference

12 December 2020

Neurotoxicity induces cleavage of p35 to p25 by calpain

1 reference

12 December 2020

Apoptosis in the nervous system

1 reference

12 December 2020

Human Nod1 confers responsiveness to bacterial lipopolysaccharides

1 reference

12 December 2020

Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

1 reference

12 December 2020

Presenilin-1 P264L knock-in mutation: differential effects on abeta production, amyloid deposition, and neuronal vulnerability.

1 reference

12 December 2020

Cellular membrane composition defines A beta-lipid interactions

1 reference

12 December 2020

Differential expression of apoptotic protease-activating factor-1 and caspase-3 genes and susceptibility to apoptosis during brain development and after traumatic brain injury.

1 reference

12 December 2020

Beta-amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand.

1 reference

12 December 2020

APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death.

1 reference

12 December 2020

Abeta(1-42) and aluminum induce stress in the endoplasmic reticulum in rabbit hippocampus, involving nuclear translocation of gadd 153 and NF-kappaB.

1 reference

12 December 2020

Rapid tyrosine phosphorylation of neuronal proteins including tau and focal adhesion kinase in response to amyloid-beta peptide exposure: involvement of Src family protein kinases.

1 reference

12 December 2020

Selective cytotoxicity of intracellular amyloid beta peptide1-42 through p53 and Bax in cultured primary human neurons

1 reference

12 December 2020

Distinct binding sites in the structure of alpha 2-macroglobulin mediate the interaction with beta-amyloid peptide and growth factors

1 reference

12 December 2020

Noradrenergic depletion potentiates beta -amyloid-induced cortical inflammation: implications for Alzheimer's disease.

1 reference

12 December 2020

Target depletion of distinct tumor necrosis factor receptor subtypes reveals hippocampal neuron death and survival through different signal transduction pathways.

1 reference

12 December 2020

Inducible nitric oxide synthase and argininosuccinate synthetase: co-induction in brain tissue of patients with Alzheimer's dementia and following stimulation with beta-amyloid 1-42 in vitro

1 reference

12 December 2020

gamma-Secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in?

1 reference

12 December 2020

Alzheimer's beta-amyloid peptides compete for insulin binding to the insulin receptor

1 reference

12 December 2020

A novel function of monomeric amyloid beta-protein serving as an antioxidant molecule against metal-induced oxidative damage

1 reference

12 December 2020

Amyloid-beta peptide is toxic to neurons in vivo via indirect mechanisms.

1 reference

12 December 2020

Calpain activity regulates the cell surface distribution of amyloid precursor protein. Inhibition of calpains enhances endosomal generation of beta-cleaved C-terminal APP fragments

1 reference

12 December 2020

Mechanisms of p75-mediated death of hippocampal neurons. Role of caspases

1 reference

12 December 2020

Caspase cleavage of members of the amyloid precursor family of proteins

1 reference

12 December 2020

Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death

1 reference

12 December 2020

ERK activation and nuclear translocation in amyloid-beta peptide- and iron-stressed neuronal cell cultures

1 reference

12 December 2020

Abeta 17-42 in Alzheimer's disease activates JNK and caspase-8 leading to neuronal apoptosis

1 reference

12 December 2020

Per-6-substituted beta-cyclodextrin libraries inhibit formation of beta-amyloid-peptide (A beta)-derived, soluble oligomers

1 reference

12 December 2020

Problems of cell death in neurodegeneration and Alzheimer's Disease

1 reference

12 December 2020

Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death

1 reference

12 December 2020

Slight impairment of Na+,K+-ATPase synergistically aggravates ceramide- and beta-amyloid-induced apoptosis in cortical neurons

1 reference

12 December 2020

22R-Hydroxycholesterol protects neuronal cells from beta-amyloid-induced cytotoxicity by binding to beta-amyloid peptide

1 reference

12 December 2020

Propentofylline protects beta-amyloid protein-induced apoptosis in cultured rat hippocampal neurons

1 reference

12 December 2020

In vitro studies of Flemish, Dutch, and wild-type beta-amyloid provide evidence for two-staged neurotoxicity

1 reference

12 December 2020

Neuregulin-1 and erbB4 immunoreactivity is associated with neuritic plaques in Alzheimer disease brain and in a transgenic model of Alzheimer disease

1 reference

12 December 2020

Stimulus-dependent activation of NF-kappaB specifies apoptosis or neuroprotection in cerebellar granule cells

1 reference

12 December 2020

Apoptotic mechanisms and antiapoptotic therapy in the MPTP model of Parkinson's disease

1 reference

12 December 2020

Apoptotic promoters and inhibitors in Alzheimer's disease: Who wins out?

1 reference

12 December 2020

Relationship between beta-amyloid degradation and the 26S proteasome in neural cells

1 reference

12 December 2020

H2O2 and 4-hydroxynonenal mediate amyloid beta-induced neuronal apoptosis by activating JNKs and p38MAPK.

1 reference

12 December 2020

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

1 reference

12 December 2020

Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration.

1 reference

12 December 2020

Physiological and pathological roles of Apaf1 and the apoptosome.

1 reference

12 December 2020

Gene therapy for Parkinson's disease

1 reference

12 December 2020

Interleukin 3 as a trophic factor for central cholinergic neurons in vitro and in vivo

1 reference

12 December 2020

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation

1 reference

12 December 2020

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

1 reference

12 December 2020

Tumor necrosis factor alpha-induced phosphorylation of I kappa B alpha is a signal for its degradation but not dissociation from NF-kappa B

1 reference

12 December 2020

A novel domain within the 55 kd TNF receptor signals cell death

1 reference

12 December 2020

Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?

1 reference

12 December 2020

Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors

1 reference

12 December 2020

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

1 reference

12 December 2020

DNA damage and apoptosis in Alzheimer's disease: colocalization with c-Jun immunoreactivity, relationship to brain area, and effect of postmortem delay.

1 reference

12 December 2020

An endogenous 55 kDa TNF receptor mediates cell death in a neural cell line.

1 reference

12 December 2020

NF-kappa B: ten years after

1 reference

12 December 2020

Dopaminergic neurons protected from degeneration by GDNF gene therapy

1 reference

12 December 2020

Inhibition of p75 tumor necrosis factor receptor by antisense oligonucleotides increases hypoxic injury and beta-amyloid toxicity in human neuronal cell line

1 reference

12 December 2020

1 reference

12 December 2020

Abeta1-40 but not Abeta1-42 levels in cortex correlate with apolipoprotein E epsilon4 allele dosage in sporadic Alzheimer's disease.

1 reference

12 December 2020

Calcium homeostasis and reactive oxygen species production in cells transformed by mitochondria from individuals with sporadic Alzheimer's disease.

1 reference

12 December 2020

Identification and characterization of an IkappaB kinase

1 reference

12 December 2020

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

1 reference

12 December 2020

Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury

1 reference

12 December 2020

Aggregated amyloid-beta protein induces cortical neuronal apoptosis and concomitant "apoptotic" pattern of gene induction.

1 reference

12 December 2020

Lipid binding to amyloid beta-peptide aggregates: preferential binding of cholesterol as compared with phosphatidylcholine and fatty acids

1 reference

12 December 2020

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

12 December 2020

Secreted beta-amyloid precursor protein counteracts the proapoptotic action of mutant presenilin-1 by activation of NF-kappaB and stabilization of calcium homeostasis

1 reference

12 December 2020

Amyloid beta-peptide stimulates nitric oxide production in astrocytes through an NFkappaB-dependent mechanism

1 reference

12 December 2020

RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase

1 reference

12 December 2020

Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

1 reference

12 December 2020

Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity

1 reference

12 December 2020

Identification of CARDIAK, a RIP-like kinase that associates with caspase-1

1 reference

12 December 2020

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

12 December 2020

Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development

1 reference

12 December 2020

Apaf1 is required for mitochondrial pathways of apoptosis and brain development

1 reference

12 December 2020

The helical domain of intestinal fatty acid binding protein is critical for collisional transfer of fatty acids to phospholipid membranes

1 reference

12 December 2020

The Presence of Amyloid β-Protein in the Detergent-Insoluble Membrane Compartment of Human Neuroblastoma Cells†

1 reference

12 December 2020

Beta-amyloid binds to p57NTR and activates NFkappaB in human neuroblastoma cells

1 reference

12 December 2020

10.1523/JNEUROSCI.4580-03.2004

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14973251%20AND%20SRC:MED&resulttype=core&format=json

23 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14973251%20AND%20SRC:MED&resulttype=core&format=json

23 November 2019

PubMed publication ID

14973251

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14973251%20AND%20SRC:MED&resulttype=core&format=json