(Q48453986)

11 February 2018

title

The Alzheimer-like phosphorylation of tau protein reduces microtubule binding and involves Ser-Pro and Thr-Pro motifs (English)

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20 October 2022

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https://api.crossref.org/works/10.1016/0014-5793(92)80767-B

20 October 2022

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https://api.crossref.org/works/10.1016/0014-5793(92)80767-B

20 October 2022

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https://api.crossref.org/works/10.1016/0014-5793(92)80767-B

20 October 2022

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https://api.crossref.org/works/10.1016/0014-5793(92)80767-B

20 October 2022

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https://api.crossref.org/works/10.1016/0014-5793(92)80767-B

20 October 2022

Mandelkow EM

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11 February 2018

author name string

N. Gustke

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1644173

20 October 2022

B. Steiner

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1644173

20 October 2022

E. M. Mandelkow

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1644173

20 October 2022

J. Biernat

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1644173

20 October 2022

H. E. Meyer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1644173

20 October 2022

M. Goedert

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1644173

20 October 2022

E. Mandelkow

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1644173

20 October 2022

language of work or name

English

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publication date

1 July 1992

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11 February 2018

28 July 1992

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1644173

full work available at URL

20 October 2022

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1016%2F0014-5793%2892%2980767-B

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https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1016%2F0014-5793(92)80767-B

20 October 2022

1 reference

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http://onlinelibrary.wiley.com/wol1/doi/10.1016/0014-5793(92)80767-B/fullpdf

20 October 2022

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https://api.crossref.org/works/10.1016/0014-5793(92)80767-B

20 October 2022

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11 February 2018

volume

307

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11 February 2018

issue

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11 February 2018

page(s)

199-205

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11 February 2018

Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics

cites work

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2892%2980767-B

Neuropathological stageing of Alzheimer-related changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2892%2980767-B

A68 proteins in Alzheimer's disease are composed of several tau isoforms in a phosphorylated state which affects their electrophoretic mobilities

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2892%2980767-B

Tau protein binds to microtubules through a flexible array of distributed weak sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2892%2980767-B

Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2892%2980767-B

Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2892%2980767-B

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2892%2980767-B

Neurofibrillary tangles and β-amyloid deposits in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2892%2980767-B

A preparation of Alzheimer paired helical filaments that displays distinct tau proteins by polyacrylamide gel electrophoresis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2892%2980767-B

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2892%2980767-B

Tau protein becomes long and stiff upon phosphorylation: correlation between paracrystalline structure and degree of phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2892%2980767-B

Tau consists of a set of proteins with repeated C-terminal microtubule-binding domains and variable N-terminal domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2892%2980767-B

Tau proteins: the molecular structure and mode of binding on microtubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2892%2980767-B

A novel tubulin-dependent protein kinase forming a paired helical filament epitope on tau

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2892%2980767-B

A serine/threonine proline kinase activity is included in the tau protein kinase fraction forming a paired helical filament epitope

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2892%2980767-B

Epitopes that span the tau molecule are shared with paired helical filaments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2892%2980767-B

Tau protein and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2892%2980767-B

Structural stability of paired helical filaments requires microtubule-binding domains of Tau: A model for self-association

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2892%2980767-B

The primary structure and heterogeneity of tau protein from mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2892%2980767-B

A68: a major subunit of paired helical filaments and derivatized forms of normal Tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2892%2980767-B

Phosphorylation-dependent epitopes of neurofilament antibodies on tau protein and relationship with Alzheimer tau

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2892%2980767-B

Tubulin domains probed by limited proteolysis and subunit-specific antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2892%2980767-B

Use of T7 RNA polymerase to direct expression of cloned genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2892%2980767-B

Neurofibrillary tangles of Alzheimer disease share antigenic determinants with the axonal microtubule-associated protein tau (tau)

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2892%2980767-B

Location and sequence characterization of the major phosphorylation sites of the high molecular mass neurofilament proteins M and H

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2892%2980767-B

Determination and location of phosphoserine in proteins and peptides by conversion to S-ethylcysteine

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2F0014-5793%2892%2980767-B

The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/0014-5793(92)80767-B

Phosphorylation of microtubule-associated protein tau: identification of the site for Ca2(+)-calmodulin dependent kinase and relationship with tau phosphorylation in Alzheimer tangles.

20 October 2022

1 reference

https://api.crossref.org/works/10.1016/0014-5793(92)80767-B

20 October 2022

Identifiers

1 reference

11 February 2018

1 reference

11 February 2018