(Q48444036)

English

Small changes in ambient temperature cause large changes in 3,4-methylenedioxymethamphetamine (MDMA)-induced serotonin neurotoxicity and core body temperature in the rat.

scientific article published in July 1998

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/9634574

0 references

Small changes in ambient temperature cause large changes in 3,4-methylenedioxymethamphetamine (MDMA)-induced serotonin neurotoxicity and core body temperature in the rat (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792575&resulttype=core&format=json

12 May 2020

0 references

1 reference

based on heuristic

inferred from title

toxic encephalopathy

1 reference

based on heuristic

inferred from title

author name string

J E Malberg

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792575&resulttype=core&format=json

12 May 2020

L S Seiden

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792575&resulttype=core&format=json

12 May 2020

language of work or name

0 references

publication date

1 July 1998

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/9634574

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792575&resulttype=core&format=json

12 May 2020

18

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792575&resulttype=core&format=json

12 May 2020

13

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792575&resulttype=core&format=json

12 May 2020

5086-5094

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792575&resulttype=core&format=json

12 May 2020

Body temperature effect on methylenedioxymethamphetamine-induced acute decrease in tryptophan hydroxylase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adverse reactions with 3,4-methylenedioxymethamphetamine (MDMA; 'ecstasy').

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain: immunocytochemical evidence for neurotoxicity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of 3,4-methylenedioxymethamphetamine on autonomic thermoregulatory responses of the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of hypothermia in the mechanism of protection against serotonergic toxicity. I. Experiments using 3,4-methylenedioxymethamphetamine, dizocilpine, CGS 19755 and NBQX

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Environment-, drug- and stress-induced alterations in body temperature affect the neurotoxicity of substituted amphetamines in the C57BL/6J mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic and thermoregulatory responses of the rat maintained in acrylic or wire-screen cages: implications for pharmacological studies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactive oxygen species and the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypothermia prevents the ischemia-induced translocation and inhibition of protein kinase C in the rat striatum.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylenedioxymethamphetamine-induced serotonin deficits are followed by partial recovery over a 52-week period. Part II: Radioligand binding and autoradiography studies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The serotonin syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of oxygen-based radicals in methamphetamine-induced neurotoxicity: evidence from the use of CuZnSOD transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic modulation of brain temperature: relevance to ischemic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of telemetry to record body temperature and activity in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Co-administration of MDMA with drugs that protect against MDMA neurotoxicity produces different effects on body temperature in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical and histological evidence that methylenedioxymethylamphetamine (MDMA) is toxic to neurons in the rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of dopamine, norepinephrine, serotonin and their major metabolic products in rat brain by reverse-phase ion-pair high performance liquid chromatography with electrochemical detection

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of hypothermia in the mechanism of protection against serotonergic toxicity. II. Experiments with methamphetamine, p-chloroamphetamine, fenfluramine, dizocilpine and dextromethorphan

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of ambient temperature on hyperthermia and hyperkinesis induced by 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toxicity and deaths from 3,4-methylenedioxymethamphetamine ("ecstasy")

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible interaction between an MAOI and "ecstasy"

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylenedioxymethamphetamine: a potentially neurotoxic amphetamine analogue

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role for excitatory amino acids in methamphetamine-induced nigrostriatal dopaminergic toxicity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5‐HT loss in rat brain following 3, 4‐methylenedioxymethamphetamine (MDMA), p‐chloroamphetamine and fenfluramine administration and effects of chlormethiazole and dizocilpine

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MK-801 reduced cerebral ischemic injury by inducing hypothermia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Review of the pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA or "Ecstasy").

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of 6-hydroxydopamine in caudate nucleus of the rat brain after a single large dose of methylamphetamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MDMA induced hyperthermia: report of a fatality and review of current therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temperature dependence of hypoxia-induced calcium accumulation in gerbil hippocampal slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The molecular mechanism of "ecstasy" [3,4-methylenedioxy-methamphetamine (MDMA)]: serotonin transporters are targets for MDMA-induced serotonin release

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of temperature in the rat by rectal probe and telemetry yields compatible results

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5,6-Dihydroxytryptamine, a serotonergic neurotoxin, is formed endogenously in the rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Individual differences in dopamine release but not rotational behavior correlate with extracellular amphetamine levels in caudate putamen in unlesioned rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of hypothermia or anesthetics on hippocampal glutamate and glycine concentrations after repeated transient global cerebral ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular serotonin levels change with behavioral state but not with pyrogen-induced hyperthermia

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

3,4-Methylenedioxymethamphetamine ('Ecstasy') promotes the translocation of protein kinase C (PKC): requirement of viable serotonin nerve terminals

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The influence of environmental temperature on the transient effects of methamphetamine on dopamine levels and dopamine release in rat striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ecstasy, the serotonin syndrome, and neuroleptic malignant syndrome--a possible link?

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotoxicity of the psychedelic amphetamine, methylenedioxymethamphetamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain temperature alters hydroxyl radical production during cerebral ischemia/reperfusion in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of endogenous dopamine in the central serotonergic deficits induced by 3,4-methylenedioxymethamphetamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypothermia, metabolic stress, and NMDA-mediated excitotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Small differences in intraischemic brain temperature critically determine the extent of ischemic neuronal injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of Free Radical Activity During Transient Global Ischemia and Recirculation: Effects of Intraischemic Brain Temperature Modulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylenedioxymethamphetamine-induced serotonin deficits are followed by partial recovery over a 52-week period. Part I: Synaptosomal uptake and tissue concentrations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional subsensitivity of 5-HT2A and 5-HT2C receptors mediating hyperthermia following acute and chronic treatment with 5-HT2A/2C receptor antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of ascorbate and cysteine on the 3,4-methylenedioxymethamphetamine-induced depletion of brain serotonin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low environmental temperatures or pharmacologic agents that produce hypothermia decrease methamphetamine neurotoxicity in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of the R(-) and S(+) isomers of MDA and MDMA on phosphatidyl inositol turnover in cultured cells expressing 5-HT2A or 5-HT2C receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of a cold environment or age on methamphetamine-induced dopamine release in the caudate putamen of female rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telemetric measurement of core temperature in pharmacological research: validity and reliability

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute and subchronic effects of methylenedioxymethamphetamine [(+/-)MDMA] on locomotion and serotonin syndrome behavior in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The serotonin syndrome. Implicated drugs, pathophysiology and management

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperthermia following MDMA administration in rats: effects of ambient temperature, water consumption, and chronic dosing

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

3,4-Methylenedioxymethamphetamine (MDMA, "Ecstasy"): pharmacology and toxicology in animals and humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MDMA-induced neurotoxicity: parameters of degeneration and recovery of brain serotonin neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The hyperthermic and neurotoxic effects of ‘Ecstasy’ (MDMA) and 3,4 methylenedioxyamphetamine (MDA) in the Dark Agouti (DA) rat, a model of the CYP2D6 poor metabolizer phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of protein kinase C (PKC) by 3,4-methylenedioxymethamphetamine (MDMA) occurs through the stimulation of serotonin receptors and transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevation of serum prolactin and corticosterone concentrations in the rat after the administration of 3,4-methylenedioxymethamphetamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Further studies of the role of hyperthermia in methamphetamine neurotoxicity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9634574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.18-13-05086.1998

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792575&resulttype=core&format=json

12 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792575&resulttype=core&format=json

12 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792575&resulttype=core&format=json

12 May 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q48444036&oldid=1588074905"