(Q48435483)

11 February 2018

title

Neutralizing the neurotoxic effects of exogenous and endogenous tPA. (English)

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11 February 2018

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William M Armstead

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11 February 2018

Taher Nassar

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11 February 2018

Saed Akkawi

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11 February 2018

Douglas H Smith

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11 February 2018

Xiao-Han Chen

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11 February 2018

Douglas B Cines

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11 February 2018

Abd Al-Roof Higazi

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11 February 2018

language of work or name

English

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publication date

1 September 2006

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11 February 2018

published in

Nature Neuroscience

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11 February 2018

volume

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11 February 2018

issue

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11 February 2018

page(s)

1150-1155

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11 February 2018

Thrombolytic stroke therapy: past, present, and future

cites work

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Neuronal death in the central nervous system demonstrates a non-fibrin substrate for plasmin

21 January 2018

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Reducing bleeding complications after thrombolytic therapy for stroke: clinical potential of metalloproteinase inhibitors and spin trap agents

21 January 2018

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Hemorrhagic transformation following ischemic stroke: significance, causes, and relationship to therapy and treatment

21 January 2018

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Depletion of circulating alpha(2)-antiplasmin by intravenous plasmin or immunoneutralization reduces focal cerebral ischemic injury in the absence of arterial recanalization

21 January 2018

1 reference

In vitro and in vivo effects of tPA and PAI-1 on blood vessel tone

21 January 2018

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Altered NO function contributes to impairment of uPA and tPA cerebrovasodilation after brain injury

21 January 2018

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Animate models of human head injury

21 January 2018

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Plasminogen activators contribute to age-dependent impairment of NMDA cerebrovasodilation after brain injury

21 January 2018

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Comparative effects of tissue plasminogen activator, streptokinase, and staphylokinase on cerebral ischemic infarction and pulmonary clot lysis in hamster models

21 January 2018

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Adjuvant treatment with neuroserpin increases the therapeutic window for tissue-type plasminogen activator administration in a rat model of embolic stroke

21 January 2018

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Regulation of single chain urokinase binding, internalization, and degradation by a plasminogen activator inhibitor 1-derived peptide

21 January 2018

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Guidelines for the early management of patients with ischemic stroke: 2005 guidelines update a scientific statement from the Stroke Council of the American Heart Association/American Stroke Association

21 January 2018

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Regulation of the single-chain urokinase-urokinase receptor complex activity by plasminogen and fibrin: novel mechanism of fibrin specificity.

21 January 2018

1 reference

Mouse model of microembolic stroke and reperfusion

21 January 2018

1 reference

Reduced cortical injury and edema in tissue plasminogen activator knockout mice after brain trauma

21 January 2018

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Amino acid residues that affect interaction of tissue-type plasminogen activator with plasminogen activator inhibitor 1

21 January 2018

1 reference

Age-specific therapy for traumatic injury of the immature brain: experimental approaches

21 January 2018

1 reference

Maturation of circulatory system in three mammalian models of human development

21 January 2018

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Effect of sympathetic nerve stimulation on cerebral blood flow in newborn piglets

21 January 2018

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L-NAME reduces infarction, neurological deficit and blood-brain barrier disruption following cerebral ischemia in mice.

21 January 2018

1 reference

Stereotaxic atlas of the pig brain

21 January 2018

1 reference

LRP and alphavbeta3 mediate tPA activation of smooth muscle cells

21 January 2018

1 reference

7 January 2021

Reduction of tissue plasminogen activator-induced hemorrhage and brain injury by free radical spin trapping after embolic focal cerebral ischemia in rats

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7 January 2021

Prenatal and postnatal growth and development of the central nervous system of the pig

1 reference

7 January 2021

Identification of an inhibitor of tissue-type plasminogen activator-mediated fibrinolysis in human neutrophils. A role for defensin

1 reference

7 January 2021

Identifiers

DOI

10.1038/NN1757

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11 February 2018

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11 February 2018