(Q48427578)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16957081%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

title

Protecting motor neurons from toxic insult by antagonism of adenosine A2a and Trk receptors (English)

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29 December 2019

author name string

Jelena Mojsilovic-Petrovic

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29 December 2019

Goo-Bo Jeong

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29 December 2019

Amanda Crocker

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29 December 2019

Amrita Arneja

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29 December 2019

Samuel David

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29 December 2019

David S Russell

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29 December 2019

Robert G Kalb

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29 December 2019

language of work or name

English

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publication date

1 September 2006

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29 December 2019

published in

Journal of Neuroscience

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29 December 2019

volume

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29 December 2019

issue

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29 December 2019

page(s)

9250-9263

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Regulation of tyrosine kinase cascades by G-protein-coupled receptors.

29 December 2019

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Adenosine A(2A) receptor antagonists KF17837 and KW-6002 potentiate rotation induced by dopaminergic drugs in hemi-Parkinsonian rats

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Activation of MAPKs by angiotensin II in vascular smooth muscle cells. Metalloprotease-dependent EGF receptor activation is required for activation of ERK and p38 MAPK but not for JNK

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12 December 2020

The role and regulation of adenosine in the central nervous system

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Dopamine D(4) and D(2L) Receptor Stimulation of the Mitogen-Activated Protein Kinase Pathway Is Dependent on trans-Activation of the Platelet-Derived Growth Factor Receptor

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12 December 2020

Cholesterol depletion inhibits epidermal growth factor receptor transactivation by angiotensin II in vascular smooth muscle cells: role of cholesterol-rich microdomains and focal adhesions in angiotensin II signaling.

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12 December 2020

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12 December 2020

Distinctive features of Trk neurotrophin receptor transactivation by G protein-coupled receptors.

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12 December 2020

Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage

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12 December 2020

Activation of Trk neurotrophin receptor signaling by pituitary adenylate cyclase-activating polypeptides

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12 December 2020

Neuroprotection by adenosine A2A receptor blockade in experimental models of Parkinson's disease

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12 December 2020

Brain-derived neurotrophic factor triggers transcription-dependent, late phase long-term potentiation in vivo.

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12 December 2020

Lipid rafts and the control of neurotrophic factor signaling in the nervous system: variations on a theme

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12 December 2020

ACh and adenosine activate PI3-kinase in rabbit hearts through transactivation of receptor tyrosine kinases

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12 December 2020

Brain-derived neurotrophic factor induces long-lasting Ca2+-activated K+ currents in rat visual cortex neurons

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12 December 2020

Elevated levels of neurotrophins in human biceps brachii tissue of amyotrophic lateral sclerosis

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12 December 2020

Rapid effects of neurotrophic factors on calcium homeostasis in rat visceral afferent neurons

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12 December 2020

BDNF heightens the sensitivity of motor neurons to excitotoxic insults through activation of TrkB.

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12 December 2020

Mutant dynactin in motor neuron disease.

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12 December 2020

A randomized sequential trial of creatine in amyotrophic lateral sclerosis

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12 December 2020

Ligand-dependent recruitment of the ErbB4 signaling complex into neuronal lipid rafts

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12 December 2020

The AMPA receptor antagonist NBQX prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis

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12 December 2020

Adenosine A(2A) receptor antagonist treatment of Parkinson's disease

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12 December 2020

Sustained intracellular Ca2+ elevation induced by a brief BDNF application in rat visual cortex neurons

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12 December 2020

TrkB mediates BDNF-induced potentiation of neuronal necrosis in cortical culture

1 reference

12 December 2020

Up‐regulation of mitochondrial uncoupling protein 3 reveals an early muscular metabolic defect in amyotrophic lateral sclerosis

1 reference

12 December 2020

Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice

1 reference

12 December 2020

Sensitization of epidermal growth factor-induced signaling by bradykinin is mediated by c-Src. Implications for a role of lipid microdomains

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12 December 2020

Role of receptor tyrosine kinases in G-protein-coupled receptor regulation of Ras: transactivation or parallel pathways?

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12 December 2020

Progress in pursuit of therapeutic A2A antagonists: the adenosine A2A receptor selective antagonist KW6002: research and development toward a novel nondopaminergic therapy for Parkinson's disease

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12 December 2020

Genetic and pharmacological inactivation of the adenosine A2A receptor attenuates 3-nitropropionic acid-induced striatal damage

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12 December 2020

NR2A induction and NMDA receptor-dependent neuronal death by neurotrophin-4/5 in cortical cell culture

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12 December 2020

Single-agent CEP-701, a novel FLT3 inhibitor, shows biologic and clinical activity in patients with relapsed or refractory acute myeloid leukemia

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12 December 2020

Transactivation of the insulin-like growth factor-I receptor by angiotensin II mediates downstream signaling from the angiotensin II type 1 receptor to phosphatidylinositol 3-kinase

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12 December 2020

Astrocytic production of nerve growth factor in motor neuron apoptosis: implications for amyotrophic lateral sclerosis

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12 December 2020

Reactive oxygen species mediate Met receptor transactivation by G protein-coupled receptors and the epidermal growth factor receptor in human carcinoma cells

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12 December 2020

The role of G-protein coupled receptors and associated proteins in receptor tyrosine kinase signal transduction

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12 December 2020

Fyn kinase modulates synaptotoxicity, but not aberrant sprouting, in human amyloid precursor protein transgenic mice.

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12 December 2020

Caveolins: structure and function in signal transduction.

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12 December 2020

Unraveling the mechanisms involved in motor neuron degeneration in ALS

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12 December 2020

Evidence for defective energy homeostasis in amyotrophic lateral sclerosis: benefit of a high-energy diet in a transgenic mouse model

1 reference

12 December 2020

Transactivation of Trk neurotrophin receptors by G-protein-coupled receptor ligands occurs on intracellular membranes.

1 reference

12 December 2020

Src family kinase-inhibitor PP2 reduces focal ischemic brain injury

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12 December 2020

Phase I clinical trial of CEP-2563 dihydrochloride, a receptor tyrosine kinase inhibitor, in patients with refractory solid tumors

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12 December 2020

Spatial and temporal control of signaling through lipid rafts

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12 December 2020

Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity

1 reference

12 December 2020

The interplay between Src family kinases and receptor tyrosine kinases

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12 December 2020

Not so strange bedfellows: G-protein-coupled receptors and Src family kinases

1 reference

12 December 2020

A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis

1 reference

12 December 2020

Receptor tyrosine kinases are signaling intermediates of G protein-coupled receptors

1 reference

12 December 2020

BDNF-induced recruitment of TrkB receptor into neuronal lipid rafts: roles in synaptic modulation

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12 December 2020

The protean actions of neurotrophins and their receptors on the life and death of neurons

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12 December 2020

Beta-lactam antibiotics offer neuroprotection by increasing glutamate transporter expression.

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12 December 2020

Cyclic AMP controls BDNF-induced TrkB phosphorylation and dendritic spine formation in mature hippocampal neurons

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12 December 2020

Astrocyte activation by fibroblast growth factor-1 and motor neuron apoptosis: implications for amyotrophic lateral sclerosis

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12 December 2020

Transduction of receptor signals by beta-arrestins

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12 December 2020

Oxygenation inhibits the physiological tissue-protecting mechanism and thereby exacerbates acute inflammatory lung injury

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12 December 2020

Role of AMPA receptor desensitization and the side effects of a DMSO vehicle on reticulospinal EPSPs and locomotor activity

1 reference

12 December 2020

The oral antidiabetic pioglitazone protects from neurodegeneration and amyotrophic lateral sclerosis-like symptoms in superoxide dismutase-G93A transgenic mice.

1 reference

12 December 2020

Fyn kinase induces synaptic and cognitive impairments in a transgenic mouse model of Alzheimer's disease.

1 reference

12 December 2020

Enprofylline protects motor neurons from in vitro excitotoxic challenge

1 reference

12 December 2020

Bone marrow transplantation only partially restores purine metabolites to normal in adenosine deaminase-deficient patients

1 reference

12 December 2020

Protective effect of riluzole on excitatory amino acid-mediated neurotoxicity in motoneuron-enriched cultures

1 reference

12 December 2020

Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation

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12 December 2020

Acute and late neurotoxicity in the rat spinal cord in vivo induced by glutamate receptor agonists

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12 December 2020

Potentiated necrosis of cultured cortical neurons by neurotrophins

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12 December 2020

Sensory but not motor neuron deficits in mice lacking NT4 and BDNF

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12 December 2020

Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development.

1 reference

12 December 2020

Mice lacking brain-derived neurotrophic factor develop with sensory deficits

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12 December 2020

Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity

1 reference

12 December 2020

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

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12 December 2020

Neurotrophins promote motor neuron survival and are present in embryonic limb bud.

1 reference

12 December 2020

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

1 reference

12 December 2020

A new monoclonal antibody which selectively recognizes the active form of Src tyrosine kinase

1 reference

12 December 2020

Motor neurons are selectively vulnerable to AMPA/kainate receptor-mediated injury in vitro

1 reference

12 December 2020

Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis

1 reference

12 December 2020

The involvement of brain-derived neurotrophic factor in hippocampal long-term potentiation revealed by gene targeting experiments

1 reference

12 December 2020

Introduction of the glutamate receptor subunit 1 into motor neurons in vitro and in vivo using a recombinant herpes simplex virus

1 reference

12 December 2020

Abnormal cerebellar development and foliation in BDNF-/- mice reveals a role for neurotrophins in CNS patterning

1 reference

12 December 2020

Adenine nucleotides undergo rapid, quantitative conversion to adenosine in the extracellular space in rat hippocampus.

1 reference

12 December 2020

Signal characteristics of G protein-transactivated EGF receptor

1 reference

12 December 2020

Severe sensory deficits but normal CNS development in newborn mice lacking TrkB and TrkC tyrosine protein kinase receptors

1 reference

12 December 2020

Adenosine modulates hypoxia-induced responses in rat PC12 cells via the A2A receptor

1 reference

12 December 2020

The A2A adenosine receptor mediates coronary vasodilation.

1 reference

12 December 2020

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

1 reference

12 December 2020

Regional selective neuronal degeneration after protein phosphatase inhibition in hippocampal slice cultures: evidence for a MAP kinase-dependent mechanism.

1 reference

12 December 2020

Cyclic AMP elevation is sufficient to promote the survival of spinal motor neurons in vitro.

1 reference

12 December 2020

Inhibition of the p44/42 MAP kinase pathway protects hippocampal neurons in a cell-culture model of seizure activity

1 reference

12 December 2020

Glutamate potentiates the toxicity of mutant Cu/Zn-superoxide dismutase in motor neurons by postsynaptic calcium-dependent mechanisms

1 reference

12 December 2020

Caveolin interacts with Trk A and p75(NTR) and regulates neurotrophin signaling pathways

1 reference

12 December 2020

Excitotoxic Death of a Subset of Embryonic Rat Motor Neurons In Vitro

1 reference

12 December 2020

10.1523/JNEUROSCI.1856-06.2006

Identifiers

DOI

1 reference

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29 December 2019

1 reference

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29 December 2019

PubMed publication ID

16957081

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16957081%20AND%20SRC:MED&resulttype=core&format=json