(Q48386718)

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Loss of X-linked mental retardation gene oligophrenin1 in mice impairs spatial memory and leads to ventricular enlargement and dendritic spine immaturity

scientific article published in August 2007

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Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/17728457

Loss of X-linked mental retardation gene oligophrenin1 in mice impairs spatial memory and leads to ventricular enlargement and dendritic spine immaturity (English)

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Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/17728457

dendritic spine

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8

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16 May 2020

Pierre Billuart

13

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16 May 2020

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Malik Khelfaoui

1

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16 May 2020

Cécile Denis

2

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16 May 2020

Elly van Galen

3

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16 May 2020

Frédéric de Bock

4

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16 May 2020

Alain Schmitt

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16 May 2020

Christophe Houbron

6

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16 May 2020

Elise Morice

7

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16 May 2020

Ger Ramakers

9

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16 May 2020

Laurent Fagni

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16 May 2020

Jamel Chelly

11

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16 May 2020

Marika Nosten-Bertrand

12

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16 May 2020

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publication date

1 August 2007

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11 February 2018

http://europepmc.org/abstract/MED/17728457

Journal of Neuroscience

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16 May 2020

27

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16 May 2020

35

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16 May 2020

9439-9450

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16 May 2020

describes a project that uses

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6673114/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Deletion including the oligophrenin-1 gene associated with enlarged cerebral ventricles, cerebellar hypoplasia, seizures and ataxia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excess of non-right handedness among individuals with intellectual disability: experimental evidence and possible explanations

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

(Over)correction of FMR1 deficiency with YAC transgenics: behavioral and physical features

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Small GTPases Rac and Rho in the maintenance of dendritic spines and branches in hippocampal pyramidal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alcohol-induced locomotor activation in C57BL/6J, A/J, and AXB/BXA recombinant inbred mice: strain distribution patterns and quantitative trait loci analysis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of dendritic spine morphology by the rho family of small GTPases: antagonistic roles of Rac and Rho

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in ARHGEF6, encoding a guanine nucleotide exchange factor for Rho GTPases, in patients with X-linked mental retardation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of GTP loading on Rho

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cre-mediated germline mosaicism: a method allowing rapid generation of several alleles of a target gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rho GTPases in neuronal morphogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transfer and interference of motor skills in people with intellectual disability.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant loxP vectors for selectable marker recycle and conditional knock-outs

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assay of Cdc42, Rac, and Rho GTPase activation by affinity methods.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Knockout mouse model for Fxr2: a model for mental retardation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dendritic Spine Pathology: Cause or Consequence of Neurological Disorders?

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deletion of the mental retardation gene Gdi1 impairs associative memory and alters social behavior in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mapping brain asymmetry

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic hydrocephalus in rats and humans: white matter loss and behavior changes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative trait loci modulate ventricular size in the mouse brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oligophrenin 1 (OPHN1) gene mutation causes syndromic X-linked mental retardation with epilepsy, rostral ventricular enlargement and cerebellar hypoplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in the oligophrenin-1 gene (OPHN1) cause X linked congenital cerebellar hypoplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CYFIP/Sra-1 controls neuronal connectivity in Drosophila and links the Rac1 GTPase pathway to the fragile X protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The RhoGAP activity of OPHN1, a new F-actin-binding protein, is negatively controlled by its amino-terminal domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BAR domains as sensors of membrane curvature: the amphiphysin BAR structure

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific clinical and brain MRI features in mentally retarded patients with mutations in the Oligophrenin-1 gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice deficient for the synaptic vesicle protein Rab3a show impaired spatial reversal learning and increased explorative activity but none of the behavioral changes shown by mice deficient for the Rab3a regulator Gdi1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of dendritic spine motility and stability by Rac1 and Rho kinase: evidence for two forms of spine motility

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficits of neuronal density in CA1 and synaptic density in the dentate gyrus, CA3 and CA1, in a mouse model of Down syndrome.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive hyperdopaminergia is functionally associated with reduced behavioral lateralization

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rho proteins, mental retardation and the neurobiological basis of intelligence

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the Rho GTPases in neuronal development

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptogenesis on mature hippocampal dendrites occurs via filopodia and immature spines during blocked synaptic transmission

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative trait loci for novelty/stress-induced locomotor activation in recombinant inbred (RI) and recombinant congenic (RC) strains of mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three-dimensional structure of dendritic spines and synapses in rat hippocampus (CA1) at postnatal day 15 and adult ages: implications for the maturation of synaptic physiology and long-term potentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oligophrenin 1 mutations frequently cause X-linked mental retardation with cerebellar hypoplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The polarity protein PAR-3 and TIAM1 cooperate in dendritic spine morphogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hippocampal pyramidal cells in adult Fmr1 knockout mice exhibit an immature-appearing profile of dendritic spines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetics and pathophysiology of mental retardation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parallel loss of hippocampal LTD and cognitive flexibility in a genetic model of hyperdopaminergia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reimpressed selective breeding for lateralization of handedness in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Instability of a 550-base pair DNA segment and abnormal methylation in fragile X syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathobiology of cortical neurons in metabolic and unclassified amentias

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain volume estimation from serial section measurements: a comparison of methodologies

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of thick brain sections by obverse—Reverse computer microscopy: Application of a new, high clarity Golgi—Nissl stain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Handedness distribution in a nonspeaking population with mental retardation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fmr1 knockout mice: a model to study fragile X mental retardation. The Dutch-Belgian Fragile X Consortium

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic analysis of anxiety-related behaviors and responses to benzodiazepine-related drugs in AXB and BXA recombinant inbred mouse strains

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired learning in mice with abnormal short-lived plasticity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homer: a protein that selectively binds metabotropic glutamate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Proposed Test Battery and Constellations of Specific Behavioral Paradigms to Investigate the Behavioral Phenotypes of Transgenic and Knockout Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

vesl, a gene encoding VASP/Ena family related protein, is upregulated during seizure, long-term potentiation and synaptogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estimation of the numerical densities of neurons and synapses in cerebral cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A cognitive affective role for the cerebellum

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oligophrenin-1 encodes a rhoGAP protein involved in X-linked mental retardation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PAK3 mutation in nonsyndromic X-linked mental retardation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic analysis of behavioral, neuroendocrine, and biochemical parameters in inbred rodents: initial studies in Lewis and Fischer 344 rats and in A/J and C57BL/6J mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17728457

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.2029-07.2007

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673114&resulttype=core&format=json

16 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673114&resulttype=core&format=json

16 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673114&resulttype=core&format=json

16 May 2020

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