(Q47400542)

15 January 2018

title

Involvement of 3-phosphoinositide-dependent protein kinase-1 in the MEK/MAPK signal transduction pathway (English)

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15 January 2018

author name string

Saori Sato

series ordinal

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15 January 2018

Naoya Fujita

series ordinal

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15 January 2018

Takashi Tsuruo

series ordinal

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15 January 2018

language of work or name

English

0 references

publication date

2 June 2004

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15 January 2018

Journal of Biological Chemistry

number of pages

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based on heuristic

inferred from page(s)

published in

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15 January 2018

volume

279

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15 January 2018

issue

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15 January 2018

page(s)

33759-33767

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15 January 2018

The Raf/MEK/ERK signal transduction cascade as a target for chemotherapeutic intervention in leukemia

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Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

21 January 2018

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Signalling through the lipid products of phosphoinositide-3-OH kinase

21 January 2018

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Phosphoinositide 3-kinases: A conserved family of signal transducers

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Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

21 January 2018

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Identification of residues in the cysteine-rich domain of Raf-1 that control Ras binding and Raf-1 activity

21 January 2018

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The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product

21 January 2018

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Purification of a murine protein-tyrosine/threonine kinase that phosphorylates and activates the Erk-1 gene product: relationship to the fission yeast byr1 gene product

21 January 2018

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Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK.

21 January 2018

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PKB binding proteins. Getting in on the Akt.

21 January 2018

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The PI3K-PDK1 connection: more than just a road to PKB

21 January 2018

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Development of anticancer drugs targeting the MAP kinase pathway

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

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Activation of the PI3K/Akt pathway and chemotherapeutic resistance

21 January 2018

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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

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Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

21 January 2018

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Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

21 January 2018

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Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo

21 January 2018

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Interference with PDK1-Akt survival signaling pathway by UCN-01 (7-hydroxystaurosporine).

21 January 2018

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Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B

21 January 2018

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Involvement of Hsp90 in signaling and stability of 3-phosphoinositide-dependent kinase-1.

21 January 2018

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Regulation of kinase activity of 3-phosphoinositide-dependent protein kinase-1 by binding to 14-3-3

21 January 2018

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MEK5, a new target of the atypical protein kinase C isoforms in mitogenic signaling

21 January 2018

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Modulation of Akt kinase activity by binding to Hsp90

21 January 2018

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RNA interference is a functional pathway with therapeutic potential in human myeloid leukemia cell lines

21 January 2018

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Use of RNA interference-mediated gene silencing and adenoviral overexpression to elucidate the roles of AKT/protein kinase B isoforms in insulin actions

21 January 2018

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Intracellular signalling: PDK1--a kinase at the hub of things

21 January 2018

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Different protein kinase C isoforms determine growth factor specificity in neuronal cells

21 January 2018

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Activation of Raf-1 signaling by protein kinase C through a mechanism involving Raf kinase inhibitory protein

21 January 2018

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Tpl-2 acts in concert with Ras and Raf-1 to activate mitogen-activated protein kinase

21 January 2018

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Mos stimulates MAP kinase in Xenopus oocytes and activates a MAP kinase kinase in vitro

21 January 2018

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MEKK1 phosphorylates MEK1 and MEK2 but does not cause activation of mitogen-activated protein kinase

21 January 2018

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Mitogen-activated protein kinases: specific messages from ubiquitous messengers

21 January 2018

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Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions

21 January 2018

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Molecular recognitions in the MAP kinase cascades

21 January 2018

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Phosphorylation and regulation of Raf by Akt (protein kinase B)

21 January 2018

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Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402055200

A phosphoserine-regulated docking site in the protein kinase RSK2 that recruits and activates PDK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402055200

Role of ERas in promoting tumour-like properties in mouse embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402055200

p21-activated kinase (PAK1) is phosphorylated and activated by 3-phosphoinositide-dependent kinase-1 (PDK1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402055200

The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402055200

21 January 2018

Identifiers

DOI

10.1074/JBC.M402055200

1 reference

15 January 2018

1 reference

15 January 2018