(Q47107616)

8 January 2018

title

Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis (English)

1 reference

8 January 2018

Middle East respiratory syndrome coronavirus

main subject

0 references

Middle East

0 references

Middle East respiratory syndrome

1 reference

Kari Debbink

1 reference

8 January 2018

Ralph S Baric

1 reference

8 January 2018

Sarah R Leist

1 reference

8 January 2018

Lisa E. Gralinski

Lisa E Gralinski

1 reference

8 January 2018

Boyd L Yount

Boyd L Yount

1 reference

8 January 2018

Rachel L. Graham

Rachel L Graham

1 reference

8 January 2018

Amy C Sims

Amy C Sims

1 reference

8 January 2018

Vineet D. Menachery

Vineet D Menachery

1 reference

8 January 2018

Katrina M. Waters

Katrina M Waters

1 reference

8 January 2018

Kenneth H Dinnon Iii

Kenneth H Dinnon

1 reference

8 January 2018

Eileen T. McAnarney

Eileen T McAnarney

1 reference

8 January 2018

Hugh Mitchell

Hugh D Mitchell

1 reference

8 January 2018

Adam S. Cockrell

Adam S Cockrell

1 reference

8 January 2018

Kelly G Stratton

Kelly G Stratton

1 reference

8 January 2018

publication date

15 November 2017

1 reference

8 January 2018

published in

mSphere

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8 January 2018

volume

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8 January 2018

issue

1 reference

8 January 2018

Coronavirus nonstructural protein 15 mediates evasion of dsRNA sensors and limits apoptosis in macrophages

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Mutagenesis of Coronavirus nsp14 Reveals Its Potential Role in Modulation of the Innate Immune Response.

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The dengue virus NS5 protein as a target for drug discovery

23 May 2018

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A crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication

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Coronavirus non-structural protein 16: evasion, attenuation, and possible treatments

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Polymerases of hepatitis C viruses and flaviviruses: structural and mechanistic insights and drug development

23 May 2018

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Attenuation and restoration of severe acute respiratory syndrome coronavirus mutant lacking 2'-o-methyltransferase activity

23 May 2018

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Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus

23 May 2018

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Engineering a replication-competent, propagation-defective Middle East respiratory syndrome coronavirus as a vaccine candidate

23 May 2018

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Coronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: evidence for proofreading and potential therapeutics

23 May 2018

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Release of severe acute respiratory syndrome coronavirus nuclear import block enhances host transcription in human lung cells

23 May 2018

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A live, impaired-fidelity coronavirus vaccine protects in an aged, immunocompromised mouse model of lethal disease

23 May 2018

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SARS coronavirus pathogenesis: host innate immune responses and viral antagonism of interferon

23 May 2018

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2'-O methylation of internal adenosine by flavivirus NS5 methyltransferase

23 May 2018

1 reference

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Biochemical and Structural Insights into the Mechanisms of SARS Coronavirus RNA Ribose 2′-O-Methylation by nsp16/nsp10 Protein Complex

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5687918

A double-inactivated severe acute respiratory syndrome coronavirus vaccine provides incomplete protection in mice and induces increased eosinophilic proinflammatory pulmonary response upon challenge

23 May 2018

1 reference

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Host regulatory network response to infection with highly pathogenic H5N1 avian influenza virus

23 May 2018

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Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5.

23 May 2018

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Successful vaccination strategies that protect aged mice from lethal challenge from influenza virus and heterologous severe acute respiratory syndrome coronavirus

23 May 2018

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Infidelity of SARS-CoV Nsp14-exonuclease mutant virus replication is revealed by complete genome sequencing

23 May 2018

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Immunization with an attenuated severe acute respiratory syndrome coronavirus deleted in E protein protects against lethal respiratory disease

23 May 2018

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A live attenuated severe acute respiratory syndrome coronavirus is immunogenic and efficacious in golden Syrian hamsters

23 May 2018

1 reference

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Coronavirus nonstructural protein 16 is a cap-0 binding enzyme possessing (nucleoside-2'O)-methyltransferase activity

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5687918

Generation of a replication-competent, propagation-deficient virus vector based on the transmissible gastroenteritis coronavirus genome

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5687918

An RNA cap (nucleoside-2'-O-)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5687918

Analysis of constructed E gene mutants of mouse hepatitis virus confirms a pivotal role for E protein in coronavirus assembly

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5687918

Middle East respiratory syndrome

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5687918

15 August 2018

Identifiers

DOI

10.1128/MSPHERE.00346-17

1 reference

8 January 2018

PMC publication ID

5687918

1 reference

8 January 2018

PubMed publication ID

29152578

1 reference

8 January 2018