(Q47072314)

5 January 2018

title

Genome-wide analysis of mRNAs regulated by the THO complex in Drosophila melanogaster (English)

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5 January 2018

main subject

Drosophila melanogaster

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Thoc5 Dmel_CG2980

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Thoc7 Dmel_CG17143

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Hpr1 Dmel_CG2031

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Thoc6 Dmel_CG5632

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author

Francesca D Ciccarelli

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Elisa Izaurralde

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5 January 2018

Kerstin Gari

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Jan Rehwinkel

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5 January 2018

Matthias Wilm

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Andrea Herold

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5 January 2018

Thomas Köcher

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Michaela Rode

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publication date

9 May 2004

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5 January 2018

Nature Structural & Molecular Biology

published in

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5 January 2018

volume

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issue

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5 January 2018

page(s)

558-566

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5 January 2018

A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae

cites work

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The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability

21 January 2018

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Interactions between mRNA export commitment, 3'-end quality control, and nuclear degradation

21 January 2018

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A novel yeast gene, THO2, is involved in RNA pol II transcription and provides new evidence for transcriptional elongation-associated recombination.

21 January 2018

1 reference

Molecular evidence that the eukaryotic THO/TREX complex is required for efficient transcription elongation.

21 January 2018

1 reference

The Saccharomyces cerevisiae hyperrecombination mutant hpr1Delta is synthetically lethal with two conditional alleles of the acetyl coenzyme A carboxylase gene and causes a defect in nuclear export of polyadenylated RNA.

21 January 2018

1 reference

RLR1 (THO2), required for expressing lacZ fusions in yeast, is conserved from yeast to humans and is a suppressor of SIN4.

21 January 2018

1 reference

A complex containing RNA polymerase II, Paf1p, Cdc73p, Hpr1p, and Ccr4p plays a role in protein kinase C signaling

21 January 2018

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High-copy-number expression of Sub2p, a member of the RNA helicase superfamily, suppresses hpr1-mediated genomic instability

21 January 2018

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Stable mRNP formation and export require cotranscriptional recruitment of the mRNA export factors Yra1p and Sub2p by Hpr1p

21 January 2018

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REF, an evolutionary conserved family of hnRNP-like proteins, interacts with TAP/Mex67p and participates in mRNA nuclear export.

21 January 2018

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The interplay of nuclear mRNP assembly, mRNA surveillance and export

21 January 2018

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Yra1p, a conserved nuclear RNA-binding protein, interacts directly with Mex67p and is required for mRNA export

21 January 2018

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The yeast hnRNP-Like proteins Yra1p and Yra2p participate in mRNA export through interaction with Mex67p

21 January 2018

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Splicing factor Sub2p is required for nuclear mRNA export through its interaction with Yra1p

21 January 2018

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Messenger RNAs are recruited for nuclear export during transcription

21 January 2018

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Intron status and 3'-end formation control cotranscriptional export of mRNA.

21 January 2018

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Early formation of mRNP: license for export or quality control?

21 January 2018

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Cotranscriptionally Formed DNA:RNA Hybrids Mediate Transcription Elongation Impairment and Transcription-Associated Recombination

21 January 2018

1 reference

Comprehensive proteomic analysis of the human spliceosome

21 January 2018

1 reference

Genome-wide analysis of nuclear mRNA export pathways in Drosophila

21 January 2018

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The DExH/D box protein HEL/UAP56 is essential for mRNA nuclear export in Drosophila

21 January 2018

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REF1/Aly and the additional exon junction complex proteins are dispensable for nuclear mRNA export

21 January 2018

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The Ref/Aly proteins are dispensable for mRNA export and development in Caenorhabditis elegans

21 January 2018

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UAP56 levels affect viability and mRNA export in Caenorhabditis elegans

21 January 2018

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Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

21 January 2018

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RNA splicing is interrupted by heat shock and is rescued by heat shock protein synthesis.

21 January 2018

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Hpr1 is preferentially required for transcription of either long or G+C-rich DNA sequences in Saccharomyces cerevisiae.

21 January 2018

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The connection between transcription and genomic instability

21 January 2018

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The death domain superfamily: a tale of two interfaces?

21 January 2018

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Beta propellers: structural rigidity and functional diversity

21 January 2018

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Splicing enhances translation in mammalian cells: an additional function of the exon junction complex

21 January 2018

1 reference

Exon junction complexes mediate the enhancing effect of splicing on mRNA expression

21 January 2018

1 reference

An efficient protein complex purification method for functional proteomics in higher eukaryotes

21 January 2018

1 reference

Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

21 January 2018

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SMART 4.0: towards genomic data integration

21 January 2018

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Parent ion scans of unseparated peptide mixtures

21 January 2018

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TREX is a conserved complex coupling transcription with messenger RNA export

21 January 2018

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The protein Mago provides a link between splicing and mRNA localization.

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NSMB759

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5 January 2018

Dimensions Publication ID

1049780708

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5 January 2018