(Q47070283)

English

The transmembrane molecule kekkon 1 acts in a feedback loop to negatively regulate the activity of the Drosophila EGF receptor during oogenesis.

scientific article published in March 1999

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12 November 2019

The transmembrane molecule kekkon 1 acts in a feedback loop to negatively regulate the activity of the Drosophila EGF receptor during oogenesis (English)

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12 November 2019

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transmembrane protein

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Kekkon 1 Dmel_CG12283

1 reference

GOA release 2020-03-11

Laufey T. Amundadottir

3

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Europe PubMed Central

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12 November 2019

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C Ghiglione

1

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12 November 2019

K L Carraway

2

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12 November 2019

R E Boswell

4

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12 November 2019

N Perrimon

5

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12 November 2019

J B Duffy

6

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12 November 2019

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1 March 1999

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12 November 2019

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Europe PubMed Central

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12 November 2019

96

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12 November 2019

6

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12 November 2019

847-856

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12 November 2019

Raf acts downstream of the EGF receptor to determine dorsoventral polarity during Drosophila oogenesis.

1 reference

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Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye.

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Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects.

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A temperature-sensitive MEK mutation demonstrates the conservation of the signaling pathways activated by receptor tyrosine kinases

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The LIN-2/LIN-7/LIN-10 complex mediates basolateral membrane localization of the C. elegans EGF receptor LET-23 in vulval epithelial cells

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Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase

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A family of proteins that inhibit signalling through tyrosine kinase receptors

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Polarized signaling: basolateral receptor localization in epithelial cells by PDZ-containing proteins

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clr-1 encodes a receptor tyrosine phosphatase that negatively regulates an FGF receptor signaling pathway in Caenorhabditis elegans

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Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer

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puckered encodes a phosphatase that mediates a feedback loop regulating JNK activity during dorsal closure in Drosophila

1 reference

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Signaling pathways that establish the dorsal-ventral pattern of the Drosophila embryo

1 reference

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The Drosophila kekkon genes: novel members of both the leucine-rich repeat and immunoglobulin superfamilies expressed in the CNS.

1 reference

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Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

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7 January 2021

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There must be 50 ways to rule the signal: the case of the Drosophila EGF receptor

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Generating lineage-specific markers to study Drosophila development

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Cleavage of Chordin by Xolloid metalloprotease suggests a role for proteolytic processing in the regulation of Spemann organizer activity

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PDZ domains: targeting signalling molecules to sub-membranous sites

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The maternal ventralizing locus torpedo is allelic to faint little ball, an embryonic lethal, and encodes the Drosophila EGF receptor homolog.

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7 January 2021

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Intercellular signaling and the polarization of body axes during Drosophila oogenesis

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A gradient of nuclear localization of the dorsal protein determines dorsoventral pattern in the Drosophila embryo.

1 reference

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Spatially localized rhomboid is required for establishment of the dorsal-ventral axis in Drosophila oogenesis

1 reference

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The Drosophila spitz gene encodes a putative EGF-like growth factor involved in dorsal-ventral axis formation and neurogenesis

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Vein is a novel component in the Drosophila epidermal growth factor receptor pathway with similarity to the neuregulins

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Germ line and soma cooperate during oogenesis to establish the dorsoventral pattern of egg shell and embryo in Drosophila melanogaster

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A thousand and one roles for the Drosophila EGF receptor

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inferred from DOI database lookup

Secreted Spitz triggers the DER signaling pathway and is a limiting component in embryonic ventral ectoderm determination.

1 reference

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Inhibition of Drosophila EGF receptor activation by the secreted protein Argos.

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Recognition of unique carboxyl-terminal motifs by distinct PDZ domains

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Neurotactin functions in concert with other identified CAMs in growth cone guidance in Drosophila.

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cDNA cloning of a novel membrane glycoprotein that is expressed specifically in glial cells in the mouse brain. LIG-1, a protein with leucine-rich repeats and immunoglobulin-like domains

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A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback

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Receptor protein-tyrosine kinases and their signal transduction pathways

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Frzb, a secreted protein expressed in the Spemann organizer, binds and inhibits Wnt-8.

1 reference

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Identifiers

10.1016/S0092-8674(00)80594-2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10102272%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

release_tidjis7bbbetdbrtg2z33uy2ee

1 reference

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24 November 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10102272%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

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