(Q46835510)

25 December 2017

title

TFE3 transcriptionally activates hepatic IRS-2, participates in insulin signaling and ameliorates diabetes (English)

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25 December 2017

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25 December 2017

Hirohito Sone

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25 December 2017

Naoya Yahagi

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25 December 2017

Hitoshi Shimano

Hitoshi Shimano

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25 December 2017

Takashi Matsuzaka

Takashi Matsuzaka

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25 December 2017

Yoshimi Nakagawa

Yoshimi Nakagawa

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25 December 2017

Akimitsu Takahashi

Akimitsu Takahashi

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25 December 2017

Hideo Toyoshima

Hideo Toyoshima

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25 December 2017

Noriyuki Inoue

Noriyuki Inoue

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25 December 2017

Tomohiro Ide

Tomohiro Ide

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25 December 2017

Tomohiro Yoshikawa

Tomohiro Yoshikawa

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25 December 2017

Mika Furusawa

Mika Furusawa

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25 December 2017

Nobuhiro Yamada

Nobuhiro Yamada

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25 December 2017

author name string

Mariko Tamura

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25 December 2017

Takashi Yamamoto

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25 December 2017

Hiroaki Suzuki

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25 December 2017

language of work or name

English

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publication date

4 December 2005

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25 December 2017

published in

Nature Medicine

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25 December 2017

volume

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25 December 2017

issue

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25 December 2017

page(s)

107-113

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25 December 2017

The IRS-signalling system: a network of docking proteins that mediate insulin action

cites work

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7 January 2021

Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance

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7 January 2021

Disruption of IRS-2 causes type 2 diabetes in mice

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7 January 2021

Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.

1 reference

7 January 2021

Evidence that IRS-2 phosphorylation is required for insulin action in hepatocytes.

1 reference

7 January 2021

Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2.

1 reference

7 January 2021

The SREBP pathway--insights from Insigs and insects

1 reference

7 January 2021

Sterol regulatory element-binding proteins (SREBPs): transcriptional regulators of lipid synthetic genes

1 reference

7 January 2021

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

1 reference

7 January 2021

Sterol regulatory element-binding proteins (SREBPs): key regulators of nutritional homeostasis and insulin action

1 reference

7 January 2021

Insulin-independent induction of sterol regulatory element-binding protein-1c expression in the livers of streptozotocin-treated mice

1 reference

7 January 2021

Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse

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7 January 2021

Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lep(ob)/Lep(ob) mice

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7 January 2021

SREBPs suppress IRS-2-mediated insulin signalling in the liver

1 reference

7 January 2021

Glucose-dependent liver gene expression in upstream stimulatory factor 2 -/- mice

1 reference

7 January 2021

Essential role in vivo of upstream stimulatory factors for a normal dietary response of the fatty acid synthase gene in the liver

1 reference

7 January 2021

Prevention of diabetic alterations in transgenic mice overexpressing Myc in the liver.

1 reference

7 January 2021

Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes

1 reference

7 January 2021

Carbohydrate responsive element-binding protein (ChREBP): a key regulator of glucose metabolism and fat storage

1 reference

7 January 2021

TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer muE3 motif

1 reference

7 January 2021

Identification of E-box factor TFE3 as a functional partner for the E2F3 transcription factor

1 reference

7 January 2021

Both Max and TFE3 cooperate with Smad proteins to bind the plasminogen activator inhibitor-1 promoter, but they have opposite effects on transcriptional activity

1 reference

7 January 2021

PU.1 and an HLH family member contribute to the myeloid-specific transcription of the Fc gamma RIIIA promoter

1 reference

7 January 2021

TFEC, a basic helix-loop-helix protein, forms heterodimers with TFE3 and inhibits TFE3-dependent transcription activation

1 reference

7 January 2021

Analysis of the signaling pathway involved in the regulation of hexokinase II gene transcription by insulin

1 reference

7 January 2021

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

1 reference

7 January 2021

Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction

1 reference

7 January 2021

Regulation of PGC-1 promoter activity by protein kinase B and the forkhead transcription factor FKHR.

1 reference

7 January 2021

Overexpression of c-myc in the liver prevents obesity and insulin resistance.

1 reference

7 January 2021

Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter

1 reference

7 January 2021

A novel insulin sensitizer acts as a coligand for peroxisome proliferator-activated receptor-alpha (PPAR-alpha) and PPAR-gamma: effect of PPAR-alpha activation on abnormal lipid metabolism in liver of Zucker fatty rats

1 reference

7 January 2021

A simplified system for generating recombinant adenoviruses

1 reference

7 January 2021

Mouse hexokinase II gene: structure, cDNA, promoter analysis, and expression pattern

1 reference

7 January 2021

Cloning, human chromosomal assignment, and adipose and hepatic expression of the CL-6/INSIG1 gene

1 reference

7 January 2021

Identifiers

DOI

10.1038/NM1334

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25 December 2017

release_hgdvmra3ynfjlct62t6kb62vnq

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/hgdvmra3ynfjlct62t6kb62vnq

24 November 2022

mapped directly with Wikidata item

1 reference

25 December 2017