(Q46557363)

23 December 2017

title

Regenerating the damaged central nervous system (English)

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23 December 2017

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Horner PJ

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23 December 2017

Gage FH

series ordinal

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23 December 2017

language of work or name

English

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publication date

1 October 2000

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23 December 2017

published in

Nature

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23 December 2017

volume

407

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23 December 2017

issue

6807

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23 December 2017

page(s)

963-970

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23 December 2017

Axons from CNS neurones regenerate into PNS grafts

cites work

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7 January 2021

Mammalian neural stem cells

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7 January 2021

Engraftable human neural stem cells respond to developmental cues, replace neurons, and express foreign genes.

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7 January 2021

Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain.

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Intraspinal delivery of neurotrophin-3 using neural stem cells genetically modified by recombinant retrovirus

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Turning brain into blood: a hematopoietic fate adopted by adult neural stem cells in vivo

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Multipotent neural precursors can differentiate toward replacement of neurons undergoing targeted apoptotic degeneration in adult mouse neocortex

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Transplanted embryonic stem cells survive, differentiate and promote recovery in injured rat spinal cord

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Embryonic stem cell-derived glial precursors: a source of myelinating transplants

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Migration of exogenous immature hematopoietic cells into adult mouse brain parenchyma under GFP-expressing bone marrow chimera.

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Pluripotential hemopoietic stem cells in adult mouse brain

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Continuation of neurogenesis in the hippocampus of the adult macaque monkey

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Neurogenesis in the adult human hippocampus

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Proliferation and differentiation of progenitor cells throughout the intact adult rat spinal cord.

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7 January 2021

Stress and hippocampal neurogenesis

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7 January 2021

More hippocampal neurons in adult mice living in an enriched environment

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7 January 2021

Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus

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7 January 2021

Neurotrophin-3 and brain-derived neurotrophic factor induce oligodendrocyte proliferation and myelination of regenerating axons in the contused adult rat spinal cord.

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7 January 2021

Local recruitment of remyelinating cells in the repair of demyelination in the central nervous system

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7 January 2021

Endogenous Progenitors Remyelinate Demyelinated Axons in the Adult CNS

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7 January 2021

Induction of neurogenesis in the neocortex of adult mice

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7 January 2021

Experimental strategies to promote axonal regeneration after traumatic central nervous system injury

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7 January 2021

Spinal cord repair in adult paraplegic rats: partial restoration of hind limb function

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7 January 2021

A combination of BDNF and NT-3 promotes supraspinal axonal regeneration into Schwann cell grafts in adult rat thoracic spinal cord.

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7 January 2021

Schwann cells genetically modified to secrete human BDNF promote enhanced axonal regrowth across transected adult rat spinal cord

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7 January 2021

Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury.

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7 January 2021

Transplants of fibroblasts genetically modified to express BDNF promote regeneration of adult rat rubrospinal axons and recovery of forelimb function.

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7 January 2021

Brain-derived neurotrophic factor stimulates hindlimb stepping and sprouting of cholinergic fibers after spinal cord injury.

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7 January 2021

Collagen containing neurotrophin-3 (NT-3) attracts regrowing injured corticospinal axons in the adult rat spinal cord and promotes partial functional recovery

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7 January 2021

Activation of locomotion in adult chronic spinal rats is achieved by transplantation of embryonic raphe cells reinnervating a precise lumbar level

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7 January 2021

Functional regeneration of sensory axons into the adult spinal cord.

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7 January 2021

Nerve growth factor-hypersecreting Schwann cell grafts augment and guide spinal cord axonal growth and remyelinate central nervous system axons in a phenotypically appropriate manner that correlates with expression of L1.

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7 January 2021

Two membrane protein fractions from rat central myelin with inhibitory properties for neurite growth and fibroblast spreading

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7 January 2021

Nogo-A is a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1

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7 January 2021

The glial scar and central nervous system repair

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7 January 2021

Glial cell extracellular matrix: boundaries for axon growth in development and regeneration

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7 January 2021

Cellular and molecular bases of axonal regeneration in the fish central nervous system

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7 January 2021

Mechanisms and molecules that control growth cone guidance

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7 January 2021

Eph receptor tyrosine kinases, axon repulsion, and the development of topographic maps

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7 January 2021

Expression of the gene encoding the chemorepellent semaphorin III is induced in the fibroblast component of neural scar tissue formed following injuries of adult but not neonatal CNS.

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7 January 2021

Intracranial injury acutely induces the expression of the secreted isoform of the CNS-specific hyaluronan-binding protein BEHAB/brevican

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7 January 2021

Chondroitin sulfate proteoglycan immunoreactivity increases following spinal cord injury and transplantation

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7 January 2021

Activated macrophages and the blood-brain barrier: inflammation after CNS injury leads to increases in putative inhibitory molecules

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7 January 2021

Diffusion barriers evoked in the rat cortex by reactive astrogliosis

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7 January 2021

Degradation of chondroitin sulfate proteoglycan enhances the neurite-promoting potential of spinal cord tissue

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7 January 2021

Leukocyte infiltration, neuronal degeneration, and neurite outgrowth after ablation of scar-forming, reactive astrocytes in adult transgenic mice

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7 January 2021

Inhibition of collagen IV deposition promotes regeneration of injured CNS axons

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7 January 2021

Neurite growth inhibitors restrict plasticity and functional recovery following corticospinal tract lesions

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7 January 2021

Enhanced axonal regeneration following combined demyelination plus schwann cell transplantation therapy in the injured adult spinal cord

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7 January 2021

A therapeutic vaccine approach to stimulate axon regeneration in the adult mammalian spinal cord

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7 January 2021

Regeneration of adult axons in white matter tracts of the central nervous system

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7 January 2021

White matter of the CNS supports or inhibits neurite outgrowth in vitro depending on geometry.

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7 January 2021

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7 January 2021

Bcl-xL protects adult septal cholinergic neurons from axotomized cell death

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7 January 2021

Changes in cytoskeletal protein synthesis following axon injury and during axon regeneration

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7 January 2021

Axonal growth-associated proteins

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7 January 2021

GAP-43: an intrinsic determinant of neuronal development and plasticity

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7 January 2021

Growth-cone attraction to netrin-1 is converted to repulsion by laminin-1.

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7 January 2021

The Bcl-2 family of proteins, and the regulation of neuronal survival

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7 January 2021

Bcl-2 promotes regeneration of severed axons in mammalian CNS

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7 January 2021

In vivo regulation of axon extension and pathfinding by growth-cone calcium transients

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7 January 2021

cAMP-induced switching in turning direction of nerve growth cones.

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7 January 2021

Conversion of neuronal growth cone responses from repulsion to attraction by cyclic nucleotides.

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7 January 2021

Prior Exposure to Neurotrophins Blocks Inhibition of Axonal Regeneration by MAG and Myelin via a cAMP-Dependent Mechanism

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7 January 2021

Nerve growth factor delivery by gene transfer induces differential outgrowth of sensory, motor, and noradrenergic neurites after adult spinal cord injury

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7 January 2021

Effects of schwann cell suspension grafts on axon regeneration in subacute and chronic CNS traumatic injuries

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7 January 2021

Reactive astrocytes are substrates for the growth of adult CNS axons in the presence of elevated levels of nerve growth factor

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7 January 2021

Repair of adult rat corticospinal tract by transplants of olfactory ensheathing cells

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7 January 2021

Long-distance axonal regeneration in the transected adult rat spinal cord is promoted by olfactory ensheathing glia transplants.

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7 January 2021

Functional Recovery of Paraplegic Rats and Motor Axon Regeneration in Their Spinal Cords by Olfactory Ensheathing Glia

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7 January 2021

Regrowth of axons into the distal spinal cord through a Schwann-cell-seeded mini-channel implanted into hemisected adult rat spinal cord.

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7 January 2021

Poly(alpha-hydroxyacids) for application in the spinal cord: resorbability and biocompatibility with adult rat Schwann cells and spinal cord

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7 January 2021

Survival of chronically-injured neurons can be prolonged by treatment with neurotrophic factors

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7 January 2021

Inflammation in the CNS: balance between immunological privilege and immune responses

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7 January 2021

Neuroprotective effects of interleukin-10 following excitotoxic spinal cord injury

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7 January 2021

Inhibition of glial scarring in the injured rat brain by a recombinant human monoclonal antibody to transforming growth factor-beta2.

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7 January 2021

Inflammatory cytokines interact to modulate extracellular matrix and astrocytic support of neurite outgrowth.

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7 January 2021

Displacement of synaptic terminals from regenerating motoneurons by microglial cells

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7 January 2021

Cytokine mRNA profiles in contused spinal cord and axotomized facial nucleus suggest a beneficial role for inflammation and gliosis

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7 January 2021

Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury

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7 January 2021

Identifiers

DOI

10.1038/35039559

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23 December 2017

Dimensions Publication ID

1027174504

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23 December 2017