(Q46529487)

English

Dietary-fat-induced obesity in mice results in beta cell hyperplasia but not increased insulin release: evidence for specificity of impaired beta cell adaptation

scientific article published on 4 June 2005

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/15937671

Dietary-fat-induced obesity in mice results in beta cell hyperplasia but not increased insulin release: evidence for specificity of impaired beta cell adaptation (English)

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/15937671

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1 reference

based on heuristic

inferred from title

6

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/15937671

author name string

R L Hull

1

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/15937671

K Kodama

2

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/15937671

K M Utzschneider

3

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/15937671

D B Carr

4

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/15937671

R L Prigeon

5

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/15937671

publication date

4 June 2005

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/15937671

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/15937671

48

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/15937671

7

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/15937671

1350-1358

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/15937671

Compensatory Growth of Pancreatic -Cells in Adult Rats After Short-Term Glucose Infusion

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https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

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Increased uncoupling protein-2 levels in beta-cells are associated with impaired glucose-stimulated insulin secretion: mechanism of action

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https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

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Medical hazards of obesity

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https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

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Increased beta-cell apoptosis prevents adaptive increase in beta-cell mass in mouse model of type 2 diabetes: evidence for role of islet amyloid formation rather than direct action of amyloid

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Time course of insulin resistance associated with feeding dogs a high-fat diet

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https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

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Contribution to glucose tolerance of insulin-independent vs. insulin-dependent mechanisms in mice

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https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

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Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle

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https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

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Uncoupling protein 2 knockout mice have enhanced insulin secretory capacity after a high-fat diet

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https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

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Influence of dietary fat composition on development of insulin resistance in rats. Relationship to muscle triglyceride and omega-3 fatty acids in muscle phospholipid

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https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

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Hormone-sensitive lipase, the rate-limiting enzyme in triglyceride hydrolysis, is expressed and active in beta-cells

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https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

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Fat feeding causes widespread in vivo insulin resistance, decreased energy expenditure, and obesity in rats.

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https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

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Islet amyloid develops diffusely throughout the pancreas before becoming severe and replacing endocrine cells.

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https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

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Differential changes in islet amyloid polypeptide (amylin) and insulin mRNA expression after high-fat diet-induced insulin resistance in C57BL/6J mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

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Marked hyperleptinemia after high-fat diet associated with severe glucose intolerance in mice.

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https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

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Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance

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https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

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Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey

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https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative studies on amyloid in the islets of Langerhans

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https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

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Hormone-sensitive lipase null mice exhibit signs of impaired insulin sensitivity whereas insulin secretion is intact

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https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

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Islet amyloid, increased A-cells, reduced B-cells and exocrine fibrosis: quantitative changes in the pancreas in type 2 diabetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

based on heuristic

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Hepatocyte growth factor overexpression in the islet of transgenic mice increases beta cell proliferation, enhances islet mass, and induces mild hypoglycemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

based on heuristic

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Diet-induced changes in uncoupling proteins in obesity-prone and obesity-resistant strains of mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

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Enhancing effects of long-term elevated glucose and palmitate on stored and secreted proinsulin-to-insulin ratios in human pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

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Adaptation of beta-cell mass to substrate oversupply: enhanced function with normal gene expression

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https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

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The Ki-67 protein: from the known and the unknown

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https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

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Insufficient islet compensation to insulin resistance vs. reduced glucose effectiveness in glucose-intolerant mice

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https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

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Ethanol-induced apoptotic neurodegeneration in the developing C57BL/6 mouse brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

based on heuristic

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Reduction of glycemic potentiation. Sensitive indicator of beta-cell loss in partially pancreatectomized dogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

based on heuristic

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Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increasing triglyceride synthesis inhibits glucose-induced insulin secretion in isolated rat islets of langerhans: a study using adenoviral expression of diacylglycerol acyltransferase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

based on heuristic

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Mechanism of impaired glucose-potentiated insulin secretion in diabetic 90% pancreatectomy rats. Study using glucagonlike peptide-1 (7-37).

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

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Dissociated insulinotropic sensitivity to glucose and carbachol in high-fat diet-induced insulin resistance in C57BL/6J mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced beta-cell function contributes to impaired glucose tolerance in dogs made obese by high-fat feeding.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

based on heuristic

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beta-cell glucokinase deficiency and hyperglycemia are associated with reduced islet amyloid deposition in a mouse model of type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

based on heuristic

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Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

based on heuristic

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Pancreatic beta-cell lipotoxicity induced by overexpression of hormone-sensitive lipase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

based on heuristic

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Dietary fat predicts conversion from impaired glucose tolerance to NIDDM. The San Luis Valley Diabetes Study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

based on heuristic

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Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

based on heuristic

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Prolonged elevation of plasma free fatty acids desensitizes the insulin secretory response to glucose in vivo in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

based on heuristic

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The continuing epidemics of obesity and diabetes in the United States

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

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Islet pathology and the pathogenesis of type 1 and type 2 diabetes mellitus revisited.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

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Acute enhancement of insulin secretion by FFA in humans is lost with prolonged FFA elevation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

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Troglitazone lowers islet fat and restores beta cell function of Zucker diabetic fatty rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

based on heuristic

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Increased dietary fat promotes islet amyloid formation and beta-cell secretory dysfunction in a transgenic mouse model of islet amyloid

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Banting lecture 1988. Role of insulin resistance in human disease

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https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

based on heuristic

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Heterogeneous metabolic adaptation of C57BL/6J mice to high-fat diet

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

based on heuristic

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Defective glucose-stimulated insulin release from perifused islets of C57BL/6J mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

based on heuristic

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Increased Islet Volume but Unchanged Islet Number in ob/ob Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

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Islet beta cell expression of constitutively active Akt1/PKB alpha induces striking hypertrophy, hyperplasia, and hyperinsulinemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

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Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose

1 reference

https://pubmed.ncbi.nlm.nih.gov/15937671

12 December 2020

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Identifiers

10.1007/S00125-005-1772-9

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/15937671

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/15937671

ResearchGate publication ID

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