(Q46314249)

21 December 2017

title

Mammalian target of rapamycin (mTOR) orchestrates the defense program of innate immune cells (English)

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21 December 2017

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Carsten J Kirschning

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21 December 2017

Hermann Wagner

object named as

Hermann Wagner

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21 December 2017

author name string

Frank Schmitz

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21 December 2017

Antje Heit

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21 December 2017

Stefan Dreher

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21 December 2017

Katharina Eisenächer

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21 December 2017

Jörg Mages

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21 December 2017

Tobias Haas

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21 December 2017

Anne Krug

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21 December 2017

Klaus-Peter Janssen

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21 December 2017

language of work or name

English

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publication date

1 November 2008

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21 December 2017

European Journal of Immunology

published in

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21 December 2017

volume

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21 December 2017

issue

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21 December 2017

page(s)

2981-2992

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21 December 2017

Akt decreases lymphocyte apoptosis and improves survival in sepsis

cites work

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https://api.crossref.org/works/10.1002%2FEJI.200838761

Phosphoinositide 3-kinase: diverse roles in immune cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

PI3K-mediated negative feedback regulation of IL-12 production in DCs

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Role of phosphoinositide 3-kinase in innate immunity

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Direct extracellular interaction between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Upstream of the mammalian target of rapamycin: do all roads pass through mTOR?

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

TOR signaling in growth and metabolism

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Structure of S6 kinase 1 determines whether raptor-mTOR or rictor-mTOR phosphorylates its hydrophobic motif site

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Identification of a conserved motif required for mTOR signaling

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

4E-BP1 phosphorylation is mediated by the FRAP-p70s6k pathway and is independent of mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Toll-like receptor signalling

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Pathogen recognition and innate immunity

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTOR

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

An Atomic Model of the Interferon-β Enhanceosome

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Proinflammatory and anti-inflammatory cytokines as mediators in the pathogenesis of septic shock

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Pannexin-1-Mediated Recognition of Bacterial Molecules Activates the Cryopyrin Inflammasome Independent of Toll-like Receptor Signaling

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Versatile inducible activation system of Akt/PKB signaling pathway in mice

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Active caspase-1 is a regulator of unconventional protein secretion

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Inhibition of human B lymphocyte cell cycle progression and differentiation by rapamycin

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Rapamycin does not induce anergy but inhibits expansion and differentiation of alloreactive human T cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

PI3K is critical for the nuclear translocation of IRF-7 and type I IFN production by human plasmacytoid predendritic cells in response to TLR activation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Translational control of the innate immune response through IRF-7

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

IRF-7 is the master regulator of type-I interferon-dependent immune responses

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Cell type-specific activation of mitogen-activated protein kinases by CpG-DNA controls interleukin-12 release from antigen-presenting cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Intracellular network of phosphatidylinositol 3-kinase, mammalian target of the rapamycin/70 kDa ribosomal S6 kinase 1, and mitogen-activated protein kinases pathways for regulating mycobacteria-induced IL-23 expression in human macrophages

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

AMPK phosphorylation of raptor mediates a metabolic checkpoint

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

The TORrid affairs of viruses: effects of mammalian DNA viruses on the PI3K-Akt-mTOR signalling pathway

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Interferon-regulatory-factor 1 controls Toll-like receptor 9-mediated IFN-β production in myeloid dendritic cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838761

7 January 2021

Identifiers

DOI

10.1002/EJI.200838761

1 reference

21 December 2017

1 reference

21 December 2017