(Q46275875)

English

A phase I dose-ranging study of the pharmacokinetics, pharmacodynamics, safety, and tolerability of AVN944, an IMPDH inhibitor, in healthy male volunteers

scientific article published on 29 October 2008

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18971325

A phase I dose-ranging study of the pharmacokinetics, pharmacodynamics, safety, and tolerability of AVN944, an IMPDH inhibitor, in healthy male volunteers (English)

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18971325

pharmacodynamics

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

author name string

J Michael Hamilton

1

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18971325

Matthew W Harding

2

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18971325

Thomas Genna

3

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18971325

David K Bol

4

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18971325

publication date

29 October 2008

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18971325

The Journal of Clinical Pharmacology

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18971325

49

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18971325

1

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18971325

30-38

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18971325

Inosine monophosphate dehydrogenase expression: transcriptional regulation of the type I and type II genes

1 reference

https://api.crossref.org/works/10.1177%2F0091270008325149

21 January 2018

Comparison of bax, waf1, and IMP dehydrogenase regulation in response to wild-type p53 expression under normal growth conditions

1 reference

https://api.crossref.org/works/10.1177%2F0091270008325149

21 January 2018

Inosine-5'-monophosphate dehydrogenase is a rate-determining factor for p53-dependent growth regulation

1 reference

https://api.crossref.org/works/10.1177%2F0091270008325149

21 January 2018

Modulation of cancer pathways by inhibitors of guanylate metabolism

1 reference

https://api.crossref.org/works/10.1177%2F0091270008325149

21 January 2018

Identification of type 1 inosine monophosphate dehydrogenase as an antiangiogenic drug target

1 reference

https://api.crossref.org/works/10.1177%2F0091270008325149

21 January 2018

Differentiation of human prostate cancer PC-3 cells induced by inhibitors of inosine 5'-monophosphate dehydrogenase.

1 reference

https://api.crossref.org/works/10.1177%2F0091270008325149

21 January 2018

IMP dehydrogenase, an enzyme linked with proliferation and malignancy

1 reference

https://api.crossref.org/works/10.1177%2F0091270008325149

21 January 2018

Regulation of inosine monophosphate dehydrogenase type I and type II isoforms in human lymphocytes

1 reference

https://api.crossref.org/works/10.1177%2F0091270008325149

21 January 2018

Monitoring of inosine monophosphate dehydrogenase activity in mononuclear cells of children with acute lymphoblastic leukemia: enzymological and clinical aspects

1 reference

https://api.crossref.org/works/10.1177%2F0091270008325149

21 January 2018

Purine metabolism in myeloid precursor cells during maturation. Studies with the HL-60 cell line

1 reference

https://api.crossref.org/works/10.1177%2F0091270008325149

21 January 2018

Comparison of biochemical parameters of benzamide riboside, a new inhibitor of IMP dehydrogenase, with tiazofurin and selenazofurin

1 reference

https://api.crossref.org/works/10.1177%2F0091270008325149

21 January 2018

IMP dehydrogenase: structural schizophrenia and an unusual base

1 reference

https://api.crossref.org/works/10.1177%2F0091270008325149

21 January 2018

Mycophenolic Acid: a one hundred year odyssey from antibiotic to immunosuppressant

1 reference

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21 January 2018

Molecular mechanisms of the antiangiogenic and antitumor effects of mycophenolic acid

1 reference

https://api.crossref.org/works/10.1177%2F0091270008325149

21 January 2018

Cell differentiation and altered IMP dehydrogenase expression induced in human T-lymphoblastoid leukemia cells by mycophenolic acid and tiazofurin

1 reference

https://api.crossref.org/works/10.1177%2F0091270008325149

21 January 2018

Effects of the IMP-dehydrogenase inhibitor, Tiazofurin, in bcr-abl positive acute myelogenous leukemia. Part I. In vivo studies

1 reference

https://api.crossref.org/works/10.1177%2F0091270008325149

21 January 2018

Guanine nucleotide depletion inhibits pre-ribosomal RNA synthesis and causes nucleolar disruption

1 reference

https://api.crossref.org/works/10.1177%2F0091270008325149

21 January 2018

Identifiers

10.1177/0091270008325149

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18971325

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18971325

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