(Q46235419)

20 December 2017

title

The JAK2 variant rs10758669 in Crohn's disease: altering the intestinal barrier as one mechanism of action (English)

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20 December 2017

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Matthias Prager

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20 December 2017

Janine Büttner

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20 December 2017

Verena Haas

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20 December 2017

Daniel C Baumgart

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20 December 2017

Andreas Sturm

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20 December 2017

Martin Zeitz

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20 December 2017

Carsten Büning

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20 December 2017

publication date

9 November 2011

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20 December 2017

International Journal of Colorectal Disease

language of work

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20 December 2017

volume

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20 December 2017

issue

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20 December 2017

page(s)

565-573

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20 December 2017

Intestinal permeability in patients with Crohn's disease and their first degree relatives

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Clustering of increased small intestinal permeability in families with Crohn's disease.

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Different intestinal permeability patterns in relatives and spouses of patients with Crohn's disease: an inherited defect in mucosal defence?

21 January 2018

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Increased intestinal permeability precedes the onset of Crohn's disease in a subject with familial risk

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Genetic basis for increased intestinal permeability in families with Crohn's disease: role of CARD15 3020insC mutation?

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Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

21 January 2018

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Autophagy as an important process in gut homeostasis and Crohn's disease pathogenesis

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21 January 2018

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NOD2/CARD15 gene polymorphism in patients with inflammatory bowel disease: is Hungary different?

21 January 2018

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Pseudoallergic reactions in chronic urticaria are associated with altered gastroduodenal permeability

21 January 2018

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Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease

21 January 2018

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The JAK-STAT signaling pathway: input and output integration

21 January 2018

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A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R

21 January 2018

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A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes

21 January 2018

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A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci

21 January 2018

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Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci

21 January 2018

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IL-1beta-induced increase in intestinal epithelial tight junction permeability is mediated by MEKK-1 activation of canonical NF-kappaB pathway

21 January 2018

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Increased epithelial uptake of protein antigens in the ileum of Crohn's disease mediated by tumour necrosis factor alpha

21 January 2018

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TNF-alpha-induced increase in intestinal epithelial tight junction permeability requires NF-kappa B activation

21 January 2018

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Protection of epithelial barrier function by the Crohn's disease associated gene protein tyrosine phosphatase n2

21 January 2018

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Importance of disrupted intestinal barrier in inflammatory bowel diseases

21 January 2018

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Inflammatory bowel disease: etiology and pathogenesis

21 January 2018

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Inflammatory Bowel Disease

21 January 2018

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Unravelling the pathogenesis of inflammatory bowel disease

21 January 2018

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The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease

21 January 2018

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A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

21 January 2018

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21 January 2018

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Genetic factors in chronic inflammation: single nucleotide polymorphisms in the STAT-JAK pathway, susceptibility to DNA damage and Crohn's disease in a New Zealand population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00384-011-1345-Y

Strong evidence of a combination polymorphism of the tyrosine kinase 2 gene and the signal transducer and activator of transcription 3 gene as a DNA-based biomarker for susceptibility to Crohn's disease in the Japanese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00384-011-1345-Y

Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00384-011-1345-Y

Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis

21 January 2018

1 reference

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Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease

21 January 2018

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Human IRGM induces autophagy to eliminate intracellular mycobacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00384-011-1345-Y

Confirmation of multiple Crohn's disease susceptibility loci in a large Dutch-Belgian cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00384-011-1345-Y

Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00384-011-1345-Y

A study in three European IBD cohorts confirms that the ATG16L1 c.898A>G (p.Thr300Ala) variant is a susceptibility factor for Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00384-011-1345-Y

Polymorphism of the IRGM Gene Might Predispose to Fistulizing Behavior in Crohn's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00384-011-1345-Y

Tumour necrosis factor-alpha and interferon-gamma production measured at the single cell level in normal and inflamed human intestine

21 January 2018

1 reference

12 December 2020

Permeability in Crohn's disease: altered barrier functions in healthy relatives?

1 reference

12 December 2020

A simple classification of Crohn's disease: report of the Working Party for the World Congresses of Gastroenterology, Vienna 1998.

1 reference

12 December 2020

Is small intestinal permeability really increased in relatives of patients with Crohn's disease?

1 reference

12 December 2020

Intestinal permeability in patients with Crohn's disease and their healthy relatives

1 reference

12 December 2020

Intestinal permeability and the prediction of relapse in Crohn's disease

1 reference

12 December 2020

Positive association of genetic variants in the upstream region of NKX2-3 with Crohn's disease in Japanese patients

1 reference

12 December 2020

10.1007/S00384-011-1345-Y

Identifiers

DOI

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20 December 2017

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20 December 2017