(Q46184740)

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Angiopoietin-1 induces Kruppel-like factor 2 expression through a phosphoinositide 3-kinase/AKT-dependent activation of myocyte enhancer factor 2.

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Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/19106103

Angiopoietin-1 induces Kruppel-like factor 2 expression through a phosphoinositide 3-kinase/AKT-dependent activation of myocyte enhancer factor 2. (English)

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/19106103

Naoki Mochizuki

10

object named as

Naoki Mochizuki

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/19106103

Akiyoshi Fukamizu

7

object named as

Akiyoshi Fukamizu

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/19106103

author name string

Keisuke Sako

1

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/19106103

Shigetomo Fukuhara

2

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/19106103

Takashi Minami

3

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/19106103

Takao Hamakubo

4

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/19106103

Haihua Song

5

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/19106103

Tatsuhiko Kodama

6

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/19106103

J Silvio Gutkind

8

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/19106103

Gou Young Koh

9

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Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/19106103

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publication date

23 December 2008

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Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/19106103

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/19106103

284

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Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/19106103

9

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/19106103

5592-5601

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/19106103

Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo

1 reference

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Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis

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Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation

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Tie2 expression and phosphorylation in angiogenic and quiescent adult tissues

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21 January 2018

Functional significance of Tie2 signaling in the adult vasculature

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Signaling and functions of angiopoietin-1 in vascular protection.

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Tie2 receptor ligands, angiopoietin-1 and angiopoietin-2, modulate VEGF-induced postnatal neovascularization

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Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie2 in pathologic vascular growth

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Tie receptors and their angiopoietin ligands are context-dependent regulators of vascular remodeling

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Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1

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Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts

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The LKLF transcription factor is required for normal tunica media formation and blood vessel stabilization during murine embryogenesis

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Klf2 is an essential regulator of vascular hemodynamic forces in vivo.

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21 January 2018

KLF2 transcription factor modulates blood vessel maturation through smooth muscle cell migration

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21 January 2018

Role of Krüppel-like transcription factors in endothelial biology

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21 January 2018

Prolonged fluid shear stress induces a distinct set of endothelial cell genes, most specifically lung Krüppel-like factor (KLF2)

1 reference

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21 January 2018

Endothelial KLF2 links local arterial shear stress levels to the expression of vascular tone-regulating genes

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21 January 2018

Integration of flow-dependent endothelial phenotypes by Kruppel-like factor 2

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21 January 2018

Tumor necrosis factor alpha-mediated reduction of KLF2 is due to inhibition of MEF2 by NF-kappaB and histone deacetylases

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21 January 2018

Targeted deletion of BMK1/ERK5 in adult mice perturbs vascular integrity and leads to endothelial failure.

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Undermining the endothelium by ablation of MAPK-MEF2 signaling

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Mutation of MEF2A in an inherited disorder with features of coronary artery disease

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KLF2 Is a novel transcriptional regulator of endothelial proinflammatory activation

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21 January 2018

Kruppel-like factor 2 inhibits protease activated receptor-1 expression and thrombin-mediated endothelial activation

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21 January 2018

Inhibition of vascular permeability factor/vascular endothelial growth factor-mediated angiogenesis by the Kruppel-like factor KLF2.

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21 January 2018

Molecular mechanisms of myogenic coactivation by p300: direct interaction with the activation domain of MyoD and with the MADS box of MEF2C

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21 January 2018

Angiopoietin-1 is an antipermeability and anti-inflammatory agent in vitro and targets cell junctions

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21 January 2018

Vascular endothelial growth factor expression of intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), and E-selectin through nuclear factor-kappa B activation in endothelial cells

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21 January 2018

Angiopoietin-1 prevents VEGF-induced endothelial permeability by sequestering Src through mDia.

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21 January 2018

Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1

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21 January 2018

Angiopoietin-1 protects the adult vasculature against plasma leakage.

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21 January 2018

COMP-Ang1: a designed angiopoietin-1 variant with nonleaky angiogenic activity

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21 January 2018

MAGI-1 is required for Rap1 activation upon cell-cell contact and for enhancement of vascular endothelial cadherin-mediated cell adhesion

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A network of mitogen-activated protein kinases links G protein-coupled receptors to the c-jun promoter: a role for c-Jun NH2-terminal kinase, p38s, and extracellular signal-regulated kinase 5.

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Signaling from G protein-coupled receptors to the c-jun promoter involves the MEF2 transcription factor. Evidence for a novel c-jun amino-terminal kinase-independent pathway.

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A novel role for phosphatidylinositol 3-kinase beta in signaling from G protein-coupled receptors to Akt.

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Cyclic AMP potentiates vascular endothelial cadherin-mediated cell-cell contact to enhance endothelial barrier function through an Epac-Rap1 signaling pathway

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Signaling from G protein-coupled receptors to ERK5/Big MAPK 1 involves Galpha q and Galpha 12/13 families of heterotrimeric G proteins. Evidence for the existence of a novel Ras AND Rho-independent pathway

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Kruppel-like factor 2 as a novel mediator of statin effects in endothelial cells

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Induction of KLF2 by fluid shear stress requires a novel promoter element activated by a phosphatidylinositol 3-kinase-dependent chromatin-remodeling pathway

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BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C

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Big mitogen-activated kinase regulates multiple members of the MEF2 protein family

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Transcriptional regulation of tissue-specific genes by the ERK5 mitogen-activated protein kinase

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Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation

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Myocyte enhancer factor 2 acetylation by p300 enhances its DNA binding activity, transcriptional activity, and myogenic differentiation

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The transcription factor MEF2C-null mouse exhibits complex vascular malformations and reduced cardiac expression of angiopoietin 1 and VEGF

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Identifiers

10.1074/JBC.M806928200

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/19106103

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/19106103

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