(Q46028427)

18 December 2017

title

GTPase inhibiting mutations activate the alpha chain of Gs and stimulate adenylyl cyclase in human pituitary tumours. (English)

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18 December 2017

author name string

C A Landis

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18 December 2017

S B Masters

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18 December 2017

A Spada

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18 December 2017

A M Pace

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18 December 2017

H R Bourne

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18 December 2017

L Vallar

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18 December 2017

language of work or name

English

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publication date

1 August 1989

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18 December 2017

published in

Nature

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18 December 2017

volume

340

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18 December 2017

issue

6236

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18 December 2017

page(s)

692-696

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18 December 2017

The cyclic AMP-mediated stimulation of cell proliferation

cites work

1 reference

7 January 2021

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Discovery of a new oncogene in pituitary tumours?

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Altered Gs and adenylate cyclase activity in human GH-secreting pituitary adenomas

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A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants

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7 January 2021

ras GTPase activating protein: signal transmitter and signal terminator

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7 January 2021

Growth hormone-releasing factor stimulates proliferation of somatotrophs in vitro

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Mechanism of adenylate cyclase activation by cholera toxin: Inhibition of GTP hydrolysis at the regulatory site

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Biological and biochemical properties of human rasH genes mutated at codon 61.

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7 January 2021

Identification of receptor contact site involved in receptor-G protein coupling

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7 January 2021

A mutation that prevents GTP-dependent activation of the alpha chain of Gs.

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7 January 2021

Carboxyl terminal domain of Gs alpha specifies coupling of receptors to stimulation of adenylyl cyclase

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7 January 2021

Molecular model of the G protein alpha subunit based on the crystal structure of the HRAS protein

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7 January 2021

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7 January 2021

Identification of effector residues and a neutralizing epitope of Ha-ras-encoded p21.

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7 January 2021

Guanosine triphosphatase activating protein (GAP) interacts with the p21 ras effector binding domain

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7 January 2021

The molecular genetics of cellular oncogenes

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7 January 2021

G proteins: transducers of receptor-generated signals

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7 January 2021

Identification of a GTP-binding protein alpha subunit that lacks an apparent ADP-ribosylation site for pertussis toxin

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7 January 2021

Sequence analysis of cDNA and genomic DNA for a putative pertussis toxin-insensitive guanine nucleotide-binding regulatory protein alpha subunit

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7 January 2021

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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7 January 2021

Isolation and characterization of the human Gs alpha gene

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7 January 2021

Generation of single-stranded DNA by the polymerase chain reaction and its application to direct sequencing of the HLA-DQA locus

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7 January 2021

Rapid and efficient site-specific mutagenesis without phenotypic selection

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7 January 2021

Identifiers

DOI

10.1038/340692A0

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18 December 2017

Dimensions Publication ID

1013227566

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18 December 2017