(Q45862524)

17 December 2017

title

Nitroreductase-mediated cell ablation is very rapid and mediated by a p53-independent apoptotic pathway (English)

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17 December 2017

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17 December 2017

author name string

Gusterson B

series ordinal

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17 December 2017

Clark AJ

series ordinal

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17 December 2017

publication date

1 May 1999

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17 December 2017

published in

Gene Therapy

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17 December 2017

volume

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17 December 2017

issue

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17 December 2017

page(s)

764-770

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17 December 2017

Lymphoma regression induced by ganciclovir in mice bearing a herpes thymidine kinase transgene.

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3300873

Comparison of genetically engineered herpes simplex viruses for the treatment of brain tumors in a scid mouse model of human malignant glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3300873

Creation of drug-specific herpes simplex virus type 1 thymidine kinase mutants for gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3300873

Transgenic mice with inducible dwarfism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3300873

Genetic ablation of parietal cells in transgenic mice: a new model for analyzing cell lineage relationships in the gastric mucosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3300873

Unique spectrum of activity of 9-[(1,3-dihydroxy-2-propoxy)methyl]-guanine against herpesviruses in vitro and its mode of action against herpes simplex virus type 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3300873

Selective cell ablation in transgenic mice expression E. coli nitroreductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3300873

Expression of the bacterial nitroreductase enzyme in mammalian cells renders them selectively sensitive to killing by the prodrug CB1954.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3300873

The expression of bacterial nitroreductase in transgenic mice results in specific cell killing by the prodrug CB1954.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3300873

The bioactivation of CB 1954 and its use as a prodrug in antibody-directed enzyme prodrug therapy (ADEPT).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3300873

The bystander effect of the nitroreductase/CB1954 enzyme/prodrug system is due to a cell-permeable metabolite

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3300873

21 January 2018

p53: puzzle and paradigm

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3300873

p53 is required for radiation-induced apoptosis in mouse thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3300873

Thymocyte apoptosis induced by p53-dependent and independent pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3300873

Consequences of thyroid hormone deficiency induced by the specific ablation of thyroid follicle cells in adult transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3300873

7 January 2021

The biochemistry of cell death by apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3300873

7 January 2021

p53 status and the efficacy of cancer therapy in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3300873

7 January 2021

Apoptosis induced by γ-irradiation, but not CD4 ligation, of peripheral T lymphocytesin vivo is p53-dependent

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3300873

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3300873

1 reference

17 December 2017

Dimensions Publication ID

1023453622

0 references

1 reference

17 December 2017