(Q4393893)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20023

Sushi/SCR/CCP domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

Human complement receptor 2 (CR2/CD21) as a receptor for DNA: implications for its roles in the immune response and the pathogenesis of systemic lupus erythematosus (SLE)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20023

protein homodimerization activity

1 reference

8 April 2019

Cr2, a candidate gene in the murine Sle1c lupus susceptibility locus, encodes a dysfunctional protein

GOA

curator

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20023

virus receptor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20023

1 reference

8 April 2019

complement binding

1 reference

8 April 2019

Structure-guided identification of C3d residues essential for its binding to complement receptor 2 (CD21)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20023

transmembrane signaling receptor activity

1 reference

8 April 2019

Molecular cloning of the cDNA encoding the Epstein-Barr virus/C3d receptor (complement receptor type 2) of human B lymphocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20023

complement receptor activity

TAS

protein binding

IPI

1 reference

8 April 2019

Binding sites of the Epstein-Barr virus and C3d receptor (CR2, CD21) for its three intracellular ligands, the p53 anti-oncoprotein, the p68 calcium binding protein and the nuclear p120 ribonucleoprotein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20023

IPI

cell component

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20023

1 reference

8 April 2019

receptor complex

1 reference

8 April 2019

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins

GOA

curator

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20023

extracellular exosome

1 reference

26 September 2017

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20023&geneProductId=UniProtKB:P20023

extracellular exosome

HDA

1 reference

8 April 2019

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20023

HDA

plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20023

3 references

8 April 2019

TAS

8 April 2019

Genomic organization and polymorphisms of the human C3d/Epstein-Barr virus receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20023

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20023

8 April 2019

biological process

immune system process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20023

1 reference

8 April 2019

B cell proliferation

1 reference

8 April 2019

Binding of monoclonal antibody to the Epstein Barr virus (EBV)/CR2 receptor induces activation and differentiation of human B lymphocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20023

immune response

1 reference

8 April 2019

Molecular cloning of the cDNA encoding the Epstein-Barr virus/C3d receptor (complement receptor type 2) of human B lymphocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20023

complement activation, classical pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20023

1 reference

8 April 2019

viral entry into host cell

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20023

B cell differentiation

1 reference

8 April 2019

Binding of monoclonal antibody to the Epstein Barr virus (EBV)/CR2 receptor induces activation and differentiation of human B lymphocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20023

innate immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20023

1 reference

8 April 2019

viral process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20023

1 reference

8 April 2019

complement receptor mediated signaling pathway

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20023

signal transduction

1 reference

26 September 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20023&geneProductId=UniProtKB:P20023

regulation of complement activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20023

1 reference

8 April 2019

TAS

Gene Atlas image

PBB GE CR2 205544 s at fs.png
732 × 530; 11 KB

0 references

has part(s)

sushi/SCR/CCP domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20023

Identifiers

MeSH descriptor ID

D017464

subject named as

Receptors, Complement 3d

0 references

MeSH tree code

D12.776.543.750.705.833.610

0 references

D12.776.543.750.830.250

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

0 references

Microsoft Academic ID

0 references

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

inferred by common MeSH mappings on source and on Wikidata

1 reference

UMLS 2023