(Q43759225)

26 November 2017

title

Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha (English)

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26 November 2017

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26 November 2017

Tuttle RL

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26 November 2017

Gill NS

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26 November 2017

Pugh W

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26 November 2017

Lee JP

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26 November 2017

Koeberlein B

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26 November 2017

Furth EE

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26 November 2017

Polonsky KS

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26 November 2017

Naji A

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26 November 2017

language of work or name

English

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publication date

1 October 2001

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26 November 2017

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26 November 2017

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26 November 2017

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26 November 2017

page(s)

1133-1137

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Apoptosis and the pathogenesis of IDDM: a question of life and death

26 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNM1001-1133

7 January 2021

Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat

1 reference

https://api.crossref.org/works/10.1038%2FNM1001-1133

7 January 2021

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

1 reference

https://api.crossref.org/works/10.1038%2FNM1001-1133

7 January 2021

Disruption of IRS-2 causes type 2 diabetes in mice

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https://api.crossref.org/works/10.1038%2FNM1001-1133

7 January 2021

Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

1 reference

https://api.crossref.org/works/10.1038%2FNM1001-1133

7 January 2021

Genetic analysis of protein kinase B (AKT) in Drosophila

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https://api.crossref.org/works/10.1038%2FNM1001-1133

7 January 2021

Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB.

1 reference

https://api.crossref.org/works/10.1038%2FNM1001-1133

7 January 2021

Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FNM1001-1133

7 January 2021

Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation

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https://api.crossref.org/works/10.1038%2FNM1001-1133

7 January 2021

Mechanism of activation of protein kinase B by insulin and IGF-1

1 reference

https://api.crossref.org/works/10.1038%2FNM1001-1133

7 January 2021

Streptozotocin-Induced Pancreatic Insulitis: New Model of Diabetes Mellitus

1 reference

https://api.crossref.org/works/10.1038%2FNM1001-1133

7 January 2021

Beta-cell apoptosis is responsible for the development of IDDM in the multiple low-dose streptozotocin model

1 reference

https://api.crossref.org/works/10.1038%2FNM1001-1133

7 January 2021

From small flies come big discoveries about size control

1 reference

https://api.crossref.org/works/10.1038%2FNM1001-1133

7 January 2021

Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.

1 reference

https://api.crossref.org/works/10.1038%2FNM1001-1133

7 January 2021

Regulation of imaginal disc cell size, cell number and organ size by Drosophila class I(A) phosphoinositide 3-kinase and its adaptor

1 reference

https://api.crossref.org/works/10.1038%2FNM1001-1133

7 January 2021

Drosophila S6 kinase: a regulator of cell size

1 reference

https://api.crossref.org/works/10.1038%2FNM1001-1133

7 January 2021

Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FNM1001-1133

7 January 2021

Biological actions of IGFs in mammalian development

1 reference

https://api.crossref.org/works/10.1038%2FNM1001-1133

7 January 2021

Seminars in medicine of the Beth Israel Deaconess Medical Center. Insulin-like growth factors

1 reference

https://api.crossref.org/works/10.1038%2FNM1001-1133

7 January 2021

The conserved phosphoinositide 3-kinase pathway determines heart size in mice

1 reference

https://api.crossref.org/works/10.1038%2FNM1001-1133

7 January 2021

Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase

1 reference

https://api.crossref.org/works/10.1038%2FNM1001-1133

7 January 2021

Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNM1001-1133

7 January 2021

Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.

1 reference

https://api.crossref.org/works/10.1038%2FNM1001-1133

7 January 2021

Dynamics of beta-cell mass in the growing rat pancreas. Estimation with a simple mathematical model.

1 reference

https://api.crossref.org/works/10.1038%2FNM1001-1133

7 January 2021

Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes

1 reference

https://api.crossref.org/works/10.1038%2FNM1001-1133

7 January 2021

Differentiation-dependent suppression of platelet-derived growth factor signaling in cultured adipocytes

1 reference

https://api.crossref.org/works/10.1038%2FNM1001-1133

7 January 2021

Beta cell mass and growth after syngeneic islet cell transplantation in normal and streptozocin diabetic C57BL/6 mice

1 reference

https://api.crossref.org/works/10.1038%2FNM1001-1133

7 January 2021

Defective insulin secretion in hepatocyte nuclear factor 1alpha-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNM1001-1133

7 January 2021

Identifiers

DOI

10.1038/NM1001-1133

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26 November 2017

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