(Q43628011)

25 November 2017

title

Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model (English)

1 reference

amyotrophic lateral sclerosis

25 November 2017

main subject

1 reference

1 reference

1 reference

25 November 2017

G Scott Ralph

1 reference

25 November 2017

Pippa A Radcliffe

1 reference

25 November 2017

Denise M Day

1 reference

25 November 2017

Janine M Carthy

1 reference

25 November 2017

Marie A Leroux

1 reference

25 November 2017

Debbie C P Lee

1 reference

25 November 2017

Liang-Fong Wong

1 reference

25 November 2017

Lynsey G Bilsland

1 reference

25 November 2017

Linda Greensmith

1 reference

25 November 2017

Susan M Kingsman

1 reference

25 November 2017

Kyriacos A Mitrophanous

1 reference

25 November 2017

Nicholas D Mazarakis

1 reference

25 November 2017

language of work or name

English

0 references

publication date

13 March 2005

1 reference

25 November 2017

1 reference

25 November 2017

1 reference

25 November 2017

1 reference

25 November 2017

page(s)

429-433

1 reference

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

25 November 2017

cites work

1 reference

RNA interference-mediated silencing of mutant superoxide dismutase rescues cyclosporin A-induced death in cultured neuroblastoma cells

21 January 2018

1 reference

Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis

21 January 2018

1 reference

RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia.

21 January 2018

1 reference

siRNA-mediated gene silencing in vitro and in vivo.

21 January 2018

1 reference

Local gene knockdown in the brain using viral-mediated RNA interference.

21 January 2018

1 reference

Rabies virus glycoprotein pseudotyping of lentiviral vectors enables retrograde axonal transport and access to the nervous system after peripheral delivery

21 January 2018

1 reference

VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model

21 January 2018

1 reference

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

21 January 2018

1 reference

ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

21 January 2018

1 reference

From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

21 January 2018

1 reference

A system for stable expression of short interfering RNAs in mammalian cells

21 January 2018

1 reference

Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy

21 January 2018

1 reference

Leuprorelin rescues polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy

21 January 2018

1 reference

Transgenic mice with an expanded CAG repeat controlled by the human AR promoter show polyglutamine nuclear inclusions and neuronal dysfunction without neuronal cell death

21 January 2018

1 reference

Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model.

21 January 2018

1 reference

Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice

21 January 2018

1 reference

Stable gene transfer to the nervous system using a non-primate lentiviral vector

21 January 2018

1 reference

New methods to titrate EIAV-based lentiviral vectors

21 January 2018

1 reference

Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase

21 January 2018

1 reference

7 January 2021

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

1 reference

7 January 2021

Transduction Patterns of Pseudotyped Lentiviral Vectors in the Nervous System

1 reference

7 January 2021

A transient three-plasmid expression system for the production of high titer retroviral vectors

1 reference

7 January 2021

Estimation of nuclear population from microtome sections

1 reference

7 January 2021

Identifiers

DOI

10.1038/NM1205

1 reference

25 November 2017

1 reference