Address
:
[go:
up one dir
,
main page
]
Include Form
Remove Scripts
Session Cookies
Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q43594592)
Watch
English
Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus.
scientific article
In more languages
default for all languages
No label defined
No description defined
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11331871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11331871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
title
Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11331871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11331871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
author
Susana Llanos
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11331871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11331871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
author name string
P A Clark
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11331871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11331871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
J Rowe
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11331871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11331871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
G Peters
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11331871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11331871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
language of work or name
English
1 reference
based on heuristic
inferred from title
publication date
1 May 2001
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11331871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11331871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
published in
Nature Cell Biology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11331871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11331871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
volume
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11331871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11331871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
issue
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11331871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11331871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
page(s)
445-452
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11331871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11331871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
cites work
Tumor surveillance via the ARF-p53 pathway.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CDK inhibitors: positive and negative regulators of G1-phase progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The INK4A/ARF locus and its two gene products
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An N-terminal p14ARF peptide blocks Mdm2-dependent ubiquitination in vitro and can activate p53 in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct roles for E2F proteins in cell growth control and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p14ARF links the tumour suppressors RB and p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Contribution of two independent MDM2-binding domains in p14(ARF) to p53 stabilization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nucleolar Arf sequesters Mdm2 and activates p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunolocalization of human p14(ARF) to the granular component of the interphase nucleolus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two arginine rich domains in the p14ARF tumour suppressor mediate nucleolar localization.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 functions as a cell cycle control protein in osteosarcomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p19ARF prevents G1 cyclin-dependent kinase activation by interacting with MDM2 and activating p53 in mouse fibroblasts.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methods used to study structure and function of the nucleolus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cancer-associated mutations at the INK4a locus cancel cell cycle arrest by p16INK4a but not by the alternative reading frame protein p19ARF.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aggresomes: a cellular response to misfolded proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization and dynamics of aggresome formation by a cytosolic GFP-chimera
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a cryptic nucleolar-localization signal in MDM2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The ribosomal L5 protein is associated with mdm-2 and mdm-2-p53 complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of p53 stability by Mdm2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35074506
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/35074506
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11331871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11331871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
PubMed publication ID
11331871
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11331871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11331871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
