(Q4338679)

Osthole (English)

7 October 2016

C₁₅H₁₆O₃

1 reference

Osthole (English)

19 November 2016

CC(=CCC1=C(C=CC2=C1OC(=O)C=C2)OC)C

1 reference

Constituents, biological activities and quality control parameters of the crude extract and essential oil from Arracacia tolucensis var. multifida

Osthole (English)

19 November 2016

1 reference

Pilocarpus riedelianus

2 references

3-Methoxyfurocoumarins from Pilocarpus riedelianus

Strategies for the isolation and identification of trypanocidal compounds from the Rutales

Prangos

1 reference

Synthesis and pharmacology of monomeric coumarins and their copolymers

Prangos lipskyi

1 reference

Coumarins from the roots of Prangos lipskyi

Murraya gleniei

1 reference

Gleinene and gleinadiene, 5,7-dimethoxycoumarins from Murraya gleinei root

Apium graveolens

1 reference

Identification of eight coumarins occurring with psoralen, xanthotoxin, and bergapten on leaf surfaces

Heracleum asperum

1 reference

Coumarins of Heracleum asperum

Seseli resinosum

1 reference

HPLC analysis of coumarins in Turkish Seseli species (Umbelliferae)

Seseli gummiferum

1 reference

HPLC analysis of coumarins in Turkish Seseli species (Umbelliferae)

Seseli hartvigii

1 reference

HPLC analysis of coumarins in Turkish Seseli species (Umbelliferae)

Cnidium monnieri

15 references

Inhibition of itch-scratch response by fruits of Cnidium monnieri in mice

Comparison of micellar electrokinetic capillary chromatography and high performance liquid chromatography on fingerprint of Cnidium monnieri

Identification and structure-activity relationship studies of osthol, a cytotoxic principle from Cnidium monnieri

Coumarins from the fruits of Cnidium monnieri

Vasorelaxing effect of coumarins from Cnidium monnieri on rabbit corpus cavernosum

Effect of the plant-extract osthole on the relaxation of rabbit corpus cavernosum tissue in vitro.

Antipruritic effect of Cnidii Monnieri Fructus (fruits of Cnidium monnieri CUSSON).

Anti-allergic effects of cnidii monnieri fructus (dried fruits of Cnidium monnieri) and its major component, osthol

Inhibition of concanavalin A-induced mice hepatitis by coumarin derivatives

Osthole prevents anti-Fas antibody-induced hepatitis in mice by affecting the caspase-3-mediated apoptotic pathway

Plant antimutagenic agents, 3. Coumarins

Cytotoxic activity of coumarins from the fruits of Cnidium monnieri on leukemia cell lines

Biologically active principles of crude drugs. Anti-allergic principles in "Cnidii monnieri".

[Screening test for calcium antagonists in natural products and the active principles of Cnidii monnieri]

Coumarins from Cnidium monnieri and their antiosteoporotic activity

Thamnosma texana

1 reference

Linear furocoumarins and other constituents from thamnosma texana

Citrus funadoko

1 reference

Spectrometric elucidation of acrimarines, the first naturally occurring acridone–coumarin dimers

Daucus carota

3 references

Carrot (Daucus Carota)

Coumarins ofDaucus carota

Carrot (Daucus carota)

Skimmia laureola

1 reference

Chromones and coumarins from Skimmia laureola

Leionema ellipticum

1 reference

The occurrence of osthol in Leionema ellipticum supports its assignment to the genus Leionema (Rutaceae)

Angelica genuflexa

2 references

Platelet anti-aggregatory effects of coumarins from the roots ofAngelica genuflexa andA. gigas

Coumarins and chromones from Lomatium macrocarpum

Phebalium tuberculosum

2 references

Coumarins from Phebalium tuberculosum ssp. megaphyllum and Phebalium filifolium

Coumarins and their taxonomic value in the genus Phebalium

Limonia acidissima

1 reference

Chemical Constituents of Three Rutaceae Species from Sri Lanka

Dinosperma stipitatum

1 reference

Acetophenones and coumarins from stem bark and leaves of Melicope stipitata

Clausena excavata

3 references

Two coumarins from the root bark of Clausena excavata

Alkaloidal and other constituents from the root bark of Clausena excavata

A new carbazole alkaloid and coumarins from roots of Clausena anisata

Ticorea longiflora

1 reference

Alkaloids and coumarins from Ticorea longiflora

Atractylodes lancea

1 reference

5-Lipoxygenase and cyclooxygenase-1 inhibitory active compounds from Atractylodes lancea.

Angelica japonica

3 references

Antiproliferative constituents from umbelliferae plants. V. A new furanocoumarin and falcarindiol furanocoumarin ethers from the root of Angelica japonica

Chemical studies of Angelica japonica A. Gray. I. On the constituents of the ethyl acetate extract of the root.

Isolation and identification of lachnophyllum lactone and osthol as repellents against a sea snail.

Ferula sumbul

2 references

Coumarins and bicoumarin from Ferula sumbul: anti-HIV activity and inhibition of cytokine release

The structure of teferidin — A new ester from the fruit of Ferula tenuisecta

Ferulago capillaris

1 reference

Coumarins from Ferulago capillaris and F. brachyloba

Melicope semecarpifolia

1 reference

Quinoline alkaloids and other constituents of Melicope semecarpifolia with antiplatelet aggregation activity.

Prangos tschimganica

1 reference

Chemical constituents of Prangos tschiniganica; structure elucidation and absolute configuration of coumarin and furanocoumarin derivatives with anti-HIV activity.

Seseli transcaucasicum

1 reference

Coumarins of the roots of Libanotis transcaucasica

Prangos lophoptera

1 reference

Coumarin composition of the roots, stems, and fruit of Prangos lophoptera

Magydaris pastinacea

1 reference

Coumarins from the Fruits of Cachrys ferulacea

Leutea turcomanica

2 references

Coumarins of the roots of Ferulago turkomanica

Coumarins of Ferulago turcomanica

Ferula persica

1 reference

Phenol derivatives from the roots of Ferula persica

Archidendron chevalieri

1 reference

Sterols, triterpenes and coumarins from Archidendron chevalieri.

Seseli grandivittatum

2 references

Coumarins of the roots ofSeseli grandivittatum

Coumarin composition of Seseli grandivittatum

Zeravschania regeliana

1 reference

Coumarins ofZeravschania regeliana

Spiranthera odoratissima

1 reference

Coumarins, furoquinoline alkaloids and terpenes from Spiranthera odoratissima (Rutaceae)

Prangos bucharica

1 reference

Coumarins from the fruit of Prangos bucharica

Micromelum minutum

2 references

7-methoxycoumarins from Micromelum minutum

Micromelin, a new coumarin from Micromelum minutum (Forst. f.) Seem (family Rutaceae)

Clausena harmandiana

2 references

Five coumarins and a carbazole alkaloid from the root bark of Clausena harmandiana

Biological activity of chemical constituents from Clausena harmandiana.

Seseli foliosum

1 reference

Coumarins ofSeseli foliosum

Skimmia reevesiana

1 reference

Alkaloids and coumarins of Skimmia reevesiana

Seseli sibiricum

4 references

Sesebrinic acid, a cinnamic acid derivative from Seseli sibiricum

Components of seseli sibiricum

HPLC analysis of coumarins in Turkish Seseli species (Umbelliferae)

Über die cumarine aus angelica ursina und seseli libanotis

Clausena anisata

3 references

Coumarins from Clausena anisata

A new carbazole alkaloid and coumarins from roots of Clausena anisata

Alkaloidal and other constituents from the root bark of Clausena excavata

Pentaceras australis

1 reference

8-Prenylcoumarins: Typical secondary metabolites of the rutaceae from Pentaceras australis

Citrus grandis

1 reference

Alkaloids and coumarins of Citrus grandis

Bilacunaria microcarpa

1 reference

Coumarins and furocoumarins of the roots ofHippomarathrum microcarpum

Haplophyllum bungei

1 reference

Coumarins ofHaplophyllum bungei

Apiaceae

1 reference

Osthole Regulates Inflammatory Mediator Expression through Modulating NF-κB, Mitogen-Activated Protein Kinases, Protein Kinase C, and Reactive Oxygen Species

Heracleum candicans

2 references

Chemical studies on the root of Heracleum candicans Wall

Furanocoumarins from Heracleum crenatifolium Boissieu

Euphorbia bivonae

1 reference

Chemical constituents and antiproliferative activity of Euphorbia bivonae

Lomatium nuttallii

1 reference

Coumarins VII. The Coumarins of Lomatium Nuttallii

Pastinaca sativa

1 reference

Osthole in the seeds ofPastinaca sativa

Murraya alata

1 reference

Anti-inflammatory coumarin and benzocoumarin derivatives from Murraya alata

Heracleum pinnatum

2 references

Furanocoumarins from Heracleum crenatifolium Boissieu

Chemical studies on the root of Heracleum candicans Wall

Pentaceras australe

1 reference

8-Prenylcoumarins: Typical secondary metabolites of the rutaceae from Pentaceras australis

Angelica pubescens

6 references

Comparative study of roots ofAngelica sinensis and related umbelliferous drugs by thin layer chromatography, high-performance liquid chromatography, and liquid chromatography - mass spectrometry

Anti-inflammatory and analgesic activities from roots of Angelica pubescens

Inhibitory effects of Angelica pubescens f. biserrata on 5-lipoxygenase and cyclooxygenase

Studies on bioactive substances in crude drugs used for arthritic diseases in traditional Chinese medicine. II. Isolation and identification of an anti-inflammatory and analgesic principle from the root of Angelica pubescens Maxim

Inhibition of Platelet Thromboxane Formation and Phosphoinositides Breakdown by Osthole from Angelica pubescens

Studies on coumarins from the root of Angelica pubescens Maxim. III. Structures of various coumarins including angelin, a new prenylcoumarin.

Angelica ursina

2 references

Chemical Studies of Angelica ursina MAXIM.

Über die cumarine aus angelica ursina und seseli libanotis

Angelica dahurica

1 reference

Cytotoxic coumarins from the root of Angelica dahurica.

Ruta graveolens

1 reference

High-resolution gas-chromatographic analysis of the secondary metabolites obtained by subcritical-fluid extraction from Colombian rue (Ruta graveolens L.).

Angelica polymorpha

1 reference

On the Coumarins of the Roots of Angelica polymorpha MAXIM. (Umbelliferae)

Prangos uloptera

3 references

Coumarins from the roots of Prangos lipskyi

Chemical constituents of Prangos tschiniganica; structure elucidation and absolute configuration of coumarin and furanocoumarin derivatives with anti-HIV activity.

Coumarins from the roots of Prangos quasiperforata

pomelo

1 reference

Alkaloids and coumarins of Citrus grandis

Ferulago lutea

1 reference

Coumarins from Ferulago capillaris and F. brachyloba

Ferula moschata

2 references

Coumarins and bicoumarin from Ferula sumbul: anti-HIV activity and inhibition of cytokine release

The structure of teferidin — A new ester from the fruit of Ferula tenuisecta

Angelica archangelica

3 references

Pentane Extracts of the Roots ofAngelica archangelicaL. from France

Separation of coumarins from Archangelica officinalis in high-performance liquid chromatography and thin-layer chromatography systems

Strategy for the isolation and identification of coumarins with calcium antagonistic properties from the roots ofAngelica archangelica

Peucedanum ostruthium

3 references

Potential antimalarial candidates from African plants: and in vitro approach using Plasmodium falciparum

Identification of ostruthin from Peucedanum ostruthium rhizomes as an inhibitor of vascular smooth muscle cell proliferation

Untersuchungen über pflanzliche Fisch- und Insektengifte. V. Über die Inhaltsstoffe der Meisterwurz (Imperatoria Ostruthium)

Murraya paniculata

4 references

Constituents of Murraya exotica L. Structure elucidation of new coumarins.

The chemical composition of Murraya paniculata. The structure of five new coumarins and one new alkaloid and the stereochemistry of murrangatin and related coumarins

Coumarins from Murraya paniculata

3-Prenylindoles from Murraya paniculata and their biogenetic significance☆

Murraya exotica

1 reference

Constituents of Murraya exotica L. Structure elucidation of new coumarins.

Prangos pabularia

2 references

Coumarins and gamma-pyrone derivatives from Prangos pabularia: antibacterial activity and inhibition of cytokine release.

Investigation of the fatty oil of the seeds ofPrangos pabularia Lindl

Angelica tschimganica

1 reference

Coumarins of the roots of Archangelica tschimganica

Prangos ferulacea

2 references

Coumarins from the aerial parts of Prangos uloptera (Apiaceae)

Coumarins fromCachrys ferulaceaCollected in Sardinia

Seseli buchtormense

1 reference

Components of Libanotis buchtormensis (FISCH.) D.C. fruits

Tetrataenium canescens

2 references

Chemical studies on the root of Heracleum candicans Wall

Furanocoumarins from Heracleum crenatifolium Boissieu

Imperatoria ostruthium

1 reference

Untersuchungen über pflanzliche Fisch- und Insektengifte. V. Über die Inhaltsstoffe der Meisterwurz (Imperatoria Ostruthium)

subject has role

immunologic adjuvant

1 reference

Medical Subject Headings

MeSH descriptor ID

C046627

15 March 2018

calcium channel blocker

1 reference

Medical Subject Headings

MeSH descriptor ID

C046627

InChI=1S/C15H16O3/c1-10(2)4-7-12-13(17-3)8-5-11-6-9-14(16)18-15(11)12/h4-6,8-9H,7H2,1-3H3

15 March 2018

Identifiers

InChI

1 reference

Osthole (English)

19 November 2016

2 references

Osthole (English)

19 November 2016

ChEBI release 2020-09-01

CAS Registry Number

484-12-8

2 references

Global Substance Registration System

osthol (English)

19 November 2016

https://commonchemistry.cas.org/detail?cas_rn=484-12-8

9 April 2021

1 reference

Osthole (English)

19 November 2016

2 references

Osthole (English)

19 November 2016

ChEBI ID

69832

mapping relation type

2 references

OSTHOLE (English)

19 November 2016

International Chemical Identifier

InChI

InChI=1S/C15H16O3/c1-10(2)4-7-12-13(17-3)8-5-11-6-9-14(16)18-15(11)12/h4-6,8-9H,7H2,1-3H3

1 reference

OSTHOLE (English)

19 November 2016

2 references

inferred from InChIKey

MSBNK-Univ_Toyama-TY000090

1 reference

MassBank accession ID

0 references

SPLASH

splash10-0f89-0900000000-1ab104e7127fe620bae8

0 references

NMRShiftDB structure ID

10017715

1 reference

HSDB ID

8479

1 reference

Hazardous Substances Data Bank

28 October 2019

Osthole (English)

10 May 2021

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

DSSTOX compound identifier

0 references

0 references

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.125.338

27 December 2018

ECHA Substance Infocard ID

2H-1-Benzopyran-2-one, 7-methoxy-8-(3-methyl-2-buten-1-yl)- (English)

quotation

CAS no.: 484-12-8 (English)

100.125.338

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.125.338

27 December 2018

Guide to Pharmacology Ligand ID

2H-1-Benzopyran-2-one, 7-methoxy-8-(3-methyl-2-buten-1-yl)- (English)

quotation

CAS no.: 484-12-8 (English)

10302

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

5 February 2021

osthol

1 reference

Global Substance Registration System

Medical Subject Headings

14 March 2018

1 reference

osthol (English)

Human Metabolome Database ID

19 November 2016

HMDB0302150

2 references

based on heuristic

inferred from InChIKey

3 references

osthole (English)

7 October 2016

inferred from InChIKey

2 references

Global Substance Registration System

osthol (English)

19 November 2016

0 references

1 reference

inferred by common MeSH mappings on source and on Wikidata

osthole (English)

7 October 2016

0 references

1 reference

6 April 2020

0 references

Microsoft Academic ID

0 references

1 reference

UMLS 2023