(Q42993498)

English

Timing-dependence of insulin-receptor mitogenic versus metabolic signalling: a plausible model based on coincidence of hormone and effector binding.

scientific article published in May 1999

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scholarly article

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10215607%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

Timing-dependence of insulin-receptor mitogenic versus metabolic signalling: a plausible model based on coincidence of hormone and effector binding (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10215607%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

Pierre De Meyts

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10215607%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

author name string

Shymko RM

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10215607%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

Dumont E

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10215607%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

Dumont JE

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10215607%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

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1 May 1999

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10215607%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

Biochemical Journal

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10215607%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

339 ( Pt 3)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10215607%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

675-683

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10215607%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

Logical analysis of timing-dependent receptor signalling specificity: application to the insulin receptor metabolic and mitogenic signalling pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

Mitogenic properties of insulin and insulin analogues mediated by the insulin receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

Costimulatory B7 molecules in the pathogenesis of infectious and autoimmune diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

CD28: a signalling perspective.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

Insulin signal transduction and the IRS proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

Sustained signalling from the insulin receptor after stimulation with insulin analogues exhibiting increased mitogenic potency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

Diverse signaling pathways in the cellular actions of insulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

GTPases: a family of molecular switches and clocks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

Binding of the Ras activator son of sevenless to insulin receptor substrate-1 signaling complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

The function of GRB2 in linking the insulin receptor to Ras signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

Molecular machines integrate coincident synaptic signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

The insulin-like growth factor-I receptor. Structure, ligand-binding mechanism and signal transduction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

Insulin receptor internalization: molecular mechanisms and physiopathological implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

Role of the time factor in signaling specificity: application to mitogenic and metabolic signaling by the insulin and insulin-like growth factor-I receptor tyrosine kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

Internalization of polypeptide hormones: mechanism, intracellular localization and significance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

Kinetic properties and sites of autophosphorylation of the partially purified insulin receptor from hepatoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

Coupling of insulin binding and insulin action on glucose transport in fat cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

A mechanism for exact sensory adaptation based on receptor modification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

Pulsatile secretion of fuel-regulatory hormones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

Frequency specificity in intercellular communication. Influence of patterns of periodic signaling on target cell responsiveness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

The dissociation and degradation of internalized insulin occur in the endosomes of rat hepatoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

Binding and biological effects of insulin, insulin analogues and insulin-like growth factors in rat aortic smooth muscle cells. Comparison of maximal growth promoting activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

In vitro and in vivo potency of insulin analogues designed for clinical use.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

Receptor Binding and Tyrosine Kinase Activation by Insulin Analogues With Extreme Affinities Studied in Human Hepatoma HepG2 Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

The bioactivity of insulin analogues from in vitro receptor binding to in vivo glucose uptake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

Phospholipase C-beta 1 is a GTPase-activating protein for Gq/11, its physiologic regulator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

The turning wheel: a study in steady states

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

Site-site interactions among insulin receptors. Characterization of the negative cooperativity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

26 May 2018

Tyrosine phosphorylation of the insulin receptor during insulin-stimulated internalization in rat hepatoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220204

16 August 2018

Association of IRS-1 with the insulin receptor and the phosphatidylinositol 3'-kinase. Formation of binary and ternary signaling complexes in intact cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10215607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Co-regulation of the mitogen-activated protein kinase, extracellular signal-regulated kinase 1, and the 90-kDa ribosomal S6 kinase in PC12 cells. Distinct effects of the neurotrophic factor, nerve growth factor, and the mitogenic factor, epidermal g

1 reference

https://pubmed.ncbi.nlm.nih.gov/10215607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10215607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PC12 cells overexpressing the insulin receptor undergo insulin-dependent neuronal differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10215607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the T-type Ca2+ current by the dopamine D1 receptor in rat adrenal glomerulosa cells: requirement of the combined action of the G betagamma protein subunit and cyclic adenosine 3',5'-monophosphate

1 reference

https://pubmed.ncbi.nlm.nih.gov/10215607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation and dephosphorylation of the insulin receptor: evidence against an intrinsic phosphatase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/10215607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin rapidly stimulates tyrosine phosphorylation of a Mr-185,000 protein in intact cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10215607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophosphorylation of the insulin receptor in vitro. Designation of phosphorylation sites and correlation with receptor kinase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10215607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of the insulin receptor in permeabilized adipocytes is coupled to a rapid dephosphorylation reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/10215607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin binding to its receptor induces a conformational change in the receptor C-terminus

1 reference

https://pubmed.ncbi.nlm.nih.gov/10215607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and partial sequence analysis of pp185, the major cellular substrate of the insulin receptor tyrosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/10215607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of deactivation of photoreceptor G protein by its target enzyme and cGMP

1 reference

https://pubmed.ncbi.nlm.nih.gov/10215607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The dephosphorylation of insulin and epidermal growth factor receptors. Role of endosome-associated phosphotyrosine phosphatase(s)

1 reference

https://pubmed.ncbi.nlm.nih.gov/10215607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/0264-6021:3390675

1 reference

Europe PubMed Central

PMC publication ID

12 November 2017

10.1042/BJ3390675

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10215607%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

release_blh6r43mq5bbdmjlcbte66sjla

1 reference

https://api.fatcat.wiki/v0/release/blh6r43mq5bbdmjlcbte66sjla

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10215607%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10215607%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

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