(Q42828980)

8 November 2017

title

Structural basis of oncogenic activation caused by point mutations in the kinase domain of the MET proto-oncogene: modeling studies (English)

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8 November 2017

Miller M

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8 November 2017

Ginalski K

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8 November 2017

Lesyng B

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8 November 2017

Nakaigawa N

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8 November 2017

Schmidt L

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8 November 2017

Zbar B

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8 November 2017

language of work or name

English

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publication date

1 July 2001

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8 November 2017

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8 November 2017

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8 November 2017

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8 November 2017

page(s)

32-43

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A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

8 November 2017

cites work

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Mutation of juxtamembrane tyrosine residue 1001 suppresses loss-of-function mutations of the met receptor in epithelial cells.

21 January 2018

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The multisubstrate docking site of the MET receptor is dispensable for MET-mediated RAS signaling and cell scattering.

21 January 2018

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Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis

21 January 2018

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Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor

21 January 2018

1 reference

Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B

21 January 2018

1 reference

Germline mutation of RET codon 883 in two cases of de novo MEN 2B.

21 January 2018

1 reference

C-kit mutations and mast cell disorders. A model of activating mutations of growth factor receptors

21 January 2018

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Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas

21 January 2018

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Novel mutations of the MET proto-oncogene in papillary renal carcinomas.

21 January 2018

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Activating mutations for the met tyrosine kinase receptor in human cancer

21 January 2018

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Uncoupling signal transducers from oncogenic MET mutants abrogates cell transformation and inhibits invasive growth

21 January 2018

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Mutant Met-mediated transformation is ligand-dependent and can be inhibited by HGF antagonists

21 January 2018

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Domain movements in protein kinases

21 January 2018

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Crystal structure of the tyrosine kinase domain of the human insulin receptor

21 January 2018

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Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog

21 January 2018

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Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism

21 January 2018

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Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors

21 January 2018

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Crystal structure of an angiogenesis inhibitor bound to the FGF receptor tyrosine kinase domain.

21 January 2018

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Three-dimensional structure of the tyrosine kinase c-Src

21 January 2018

1 reference

The 2.35 A crystal structure of the inactivated form of chicken Src: a dynamic molecule with multiple regulatory interactions

21 January 2018

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Crystal structures of c-Src reveal features of its autoinhibitory mechanism

21 January 2018

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Crystal structure of the Src family tyrosine kinase Hck

21 January 2018

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Crystal structure of Hck in complex with a Src family-selective tyrosine kinase inhibitor

21 January 2018

1 reference

Structural basis for activation of human lymphocyte kinase Lck upon tyrosine phosphorylation

21 January 2018

1 reference

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

21 January 2018

1 reference

Density-functional thermochemistry. III. The role of exact exchange

21 January 2018

1 reference

Errors in protein structures

21 January 2018

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Prediction of protein side-chain rotamers from a backbone-dependent rotamer library: a new homology modeling tool

21 January 2018

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Automated analysis of interatomic contacts in proteins

21 January 2018

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Molecular docking using surface complementarity.

21 January 2018

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The mutationally activated Met receptor mediates motility and metastasis

21 January 2018

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Autoregulatory mechanisms in protein-tyrosine kinases

21 January 2018

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Crystal Structure of the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

21 January 2018

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Crystallographic and solution studies of an activation loop mutant of the insulin receptor tyrosine kinase: insights into kinase mechanism

21 January 2018

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Conformational changes in the activation loop of the insulin receptor's kinase domain

21 January 2018

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Switching signals on or off by receptor dimerization

21 January 2018

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Tumorigenesis mediated by MET mutant M1268T is inhibited by dominant-negative Src.

21 January 2018

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Essential role of Gab1 for signaling by the c-Met receptor in vivo

21 January 2018

1 reference

Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses

21 January 2018

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Signaling requirements for oncogenic forms of the Met tyrosine kinase receptor.

21 January 2018

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Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features

21 January 2018

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https://api.fatcat.wiki/v0/release/2zux4r3q55ed3h6fjpnuxuhmvy

21 January 2018

Identifiers

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30 July 2022

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Fatcat ID

release_2zux4r3q55ed3h6fjpnuxuhmvy

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Fatcat

https://api.fatcat.wiki/v0/release/2zux4r3q55ed3h6fjpnuxuhmvy

mapped directly with Wikidata item

30 July 2022

based on heuristic

https://api.fatcat.wiki/v0/release/2zux4r3q55ed3h6fjpnuxuhmvy

1 reference