(Q42742129)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16670261%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

T-bet is a critical determinant in the instability of the IL-17-secreting T-helper phenotype (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16670261%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

Maria Laura Belladonna

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16670261%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Anubhav N Mathur

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16670261%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Hua-Chen Chang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16670261%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Dimitrios G Zisoulis

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16670261%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Reuben Kapur

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16670261%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Geoffrey S Kansas

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16670261%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Mark H Kaplan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16670261%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

language of work or name

English

0 references

publication date

2 May 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16670261%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16670261%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

volume

108

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16670261%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16670261%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

page(s)

1595-1601

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16670261%20AND%20SRC:MED&resulttype=core&format=json

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

20 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

A crucial role for T-bet in selectin ligand expression in T helper 1 (Th1) cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

T-bet is required for optimal proinflammatory CD4+ T-cell trafficking.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

NFATc2 and T-bet contribute to T-helper-cell-subset-specific regulation of IL-21 expression

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

RhoH, a hematopoietic-specific Rho GTPase, regulates proliferation, survival, migration, and engraftment of hematopoietic progenitor cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

Transforming growth factor beta blocks Tec kinase phosphorylation, Ca2+ influx, and NFATc translocation causing inhibition of T cell differentiation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

CD4+ T cells mediate abscess formation in intra-abdominal sepsis by an IL-17-dependent mechanism

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

Epitope spreading in immune-mediated diseases: implications for immunotherapy

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

Up-regulation of IL-17 is associated with bioactive IL-8 expression in Helicobacter pylori-infected human gastric mucosa

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

A novel transcription factor, T-bet, directs Th1 lineage commitment

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

The Ets transcription factor ERM is Th1-specific and induced by IL-12 through a Stat4-dependent pathway.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

IL-17 stimulates granulopoiesis in mice: use of an alternate, novel gene therapy-derived method for in vivo evaluation of cytokines

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

Reversibility of T helper 1 and 2 populations is lost after long-term stimulation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

Cloning of a new cytokine that induces IFN-gamma production by T cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

TGF-beta1 inhibits T-bet induction by IFN-gamma in murine CD4+ T cells through the protein tyrosine phosphatase Src homology region 2 domain-containing phosphatase-1.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

Influence of multiplicity of infection and protein stability on retroviral vector-mediated gene expression in hematopoietic cells

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895507

Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet

16 August 2018

1 reference

12 December 2020

IL-23 and IL-12 have overlapping, but distinct, effects on murine dendritic cells

1 reference

12 December 2020

T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells

1 reference

12 December 2020

Expression of a constitutively active Stat6 in vivo alters lymphocyte homeostasis with distinct effects in T and B cells

1 reference

12 December 2020

10.1182/BLOOD-2006-04-015016

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16670261%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16670261%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

PubMed publication ID

16670261

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16670261%20AND%20SRC:MED&resulttype=core&format=json