(Q42471458)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20467442%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

Omi/HtrA2 is a positive regulator of autophagy that facilitates the degradation of mutant proteins involved in neurodegenerative diseases (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20467442%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

0 references

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20467442%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20467442%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20467442%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Q Hu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20467442%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

H Wang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20467442%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

N Man

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20467442%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

N Nukina

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20467442%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

E Fei

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20467442%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

G Wang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20467442%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

language of work or name

1 reference

14 May 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20467442%20AND%20SRC:MED&resulttype=core&format=json

Cell Death & Differentiation

2 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20467442%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20467442%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20467442%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

page(s)

1773-1784

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20467442%20AND%20SRC:MED&resulttype=core&format=json

The HtrA family of serine proteases

2 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

The HtrA Family of Proteases

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Mitochondrial protease Omi/HtrA2 enhances caspase activation through multiple pathways

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Binding specificity and regulation of the serine protease and PDZ domains of HtrA2/Omi

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Accumulation of HtrA2/Omi in neuronal and glial inclusions in brains with alpha-synucleinopathies

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

The C-terminal tail of presenilin regulates Omi/HtrA2 protease activity

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Beta-amyloid precursor protein is a direct cleavage target of HtrA2 serine protease. Implications for the physiological function of HtrA2 in the mitochondria.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Loss of autophagy in the central nervous system causes neurodegeneration in mice

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

A protein conjugation system essential for autophagy

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Autophagy is activated for cell survival after endoplasmic reticulum stress

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

α-Synuclein Is Degraded by Both Autophagy and the Proteasome

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Regulation of HAX-1 anti-apoptotic protein by Omi/HtrA2 protease during cell death

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Characterization of a novel human serine protease that has extensive homology to bacterial heat shock endoprotease HtrA and is regulated by kidney ischemia

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Protective role of autophagy in neonatal hypoxia-ischemia induced brain injury

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Regulation mechanisms and signaling pathways of autophagy

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Selective degradation of mitochondria by mitophagy

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

K15 protein of Kaposi's sarcoma-associated herpesvirus is latently expressed and binds to HAX-1, a protein with antiapoptotic function

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

The mitochondrial serine protease HtrA2/Omi: an overview

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

A monoclonal antibody that recognizes a phosphorylated epitope in Alzheimer neurofibrillary tangles, neurofilaments and tau proteins immunostains granulovacuolar degeneration

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Autophagy genes protect against disease caused by polyglutamine expansion proteins in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Chaperone-mediated autophagy in aging and disease

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Omi / HtrA2 is relevant to the selective vulnerability of striatal neurons in Huntington's disease

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Assembly of lysine 63-linked ubiquitin conjugates by phosphorylated alpha-synuclein implies Lewy body biogenesis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2010.55

7 January 2021

Identifiers

DOI

10.1038/CDD.2010.55

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20467442%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

2 February 2020

1013826228

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20467442%20AND%20SRC:MED&resulttype=core&format=json