(Q41792371)

10 October 2017

title

A UPF3-mediated regulatory switch that maintains RNA surveillance (English)

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10 October 2017

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10 October 2017

Lam Son Nguyen

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Hervé Le Hir

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Wai-Kin Chan

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10 October 2017

Angela D Bhalla

series ordinal

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10 October 2017

Lulu Huang

series ordinal

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10 October 2017

Miles F Wilkinson

series ordinal

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10 October 2017

publication date

7 June 2009

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Nature Structural & Molecular Biology

10 October 2017

published in

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10 October 2017

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10 October 2017

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10 October 2017

page(s)

747-753

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The nonsense-mediated decay RNA surveillance pathway

10 October 2017

cites work

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Nonsense-mediated mRNA decay in health and disease

21 January 2018

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Nonsense-mediated decay approaches the clinic

21 January 2018

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Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise

21 January 2018

1 reference

An alternative branch of the nonsense-mediated decay pathway

21 January 2018

1 reference

hUPF2 silencing identifies physiologic substrates of mammalian nonsense-mediated mRNA decay

21 January 2018

1 reference

NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements

21 January 2018

1 reference

The surveillance complex interacts with the translation release factors to enhance termination and degrade aberrant mRNAs

21 January 2018

1 reference

Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay

21 January 2018

1 reference

Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways

21 January 2018

1 reference

A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay

21 January 2018

1 reference

Y14 and hUpf3b form an NMD-activating complex

21 January 2018

1 reference

Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex

21 January 2018

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Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon

21 January 2018

1 reference

Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4)

21 January 2018

1 reference

X chromosomes, retrogenes and their role in male reproduction

21 January 2018

1 reference

Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay

21 January 2018

1 reference

Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation

21 January 2018

1 reference

The regulatory utilization of genetic redundancy through responsive backup circuits

21 January 2018

1 reference

Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation

21 January 2018

1 reference

Complexes between the nonsense-mediated mRNA decay pathway factor human upf1 (up-frameshift protein 1) and essential nonsense-mediated mRNA decay factors in HeLa cells

21 January 2018

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Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7

21 January 2018

1 reference

Mechanisms of translational control by the 3' UTR in development and differentiation

21 January 2018

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The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3

21 January 2018

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Paralogs and mutational robustness linked through transcriptional reprogramming

21 January 2018

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Meiotic sex chromosome inactivation

21 January 2018

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Comparison of nonsense-mediated mRNA decay efficiency in various murine tissues

21 January 2018

1 reference

Inactivation of MyoD in mice leads to up-regulation of the myogenic HLH gene Myf-5 and results in apparently normal muscle development.

21 January 2018

1 reference

Concerted regulation and molecular evolution of the duplicated SNRPB'/B and SNRPN loci

21 January 2018

1 reference

A nonimprinted Prader-Willi Syndrome (PWS)-region gene regulates a different chromosomal domain in trans but the imprinted pws loci do not alter genome-wide mRNA levels

21 January 2018

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Posttranscriptional crossregulation between Drosha and DGCR8.

21 January 2018

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Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements

21 January 2018

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EJC-independent degradation of nonsense immunoglobulin-mu mRNA depends on 3' UTR length

21 January 2018

1 reference

Rent1, a trans-effector of nonsense-mediated mRNA decay, is essential for mammalian embryonic viability

21 January 2018

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T-cell receptor sequences that elicit strong down-regulation of premature termination codon-bearing transcripts

21 January 2018

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Splicing and 3' end formation in the definition of nonsense-mediated decay-competent human beta-globin mRNPs

21 January 2018

1 reference

Separable roles for rent1/hUpf1 in altered splicing and decay of nonsense transcripts

21 January 2018

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An eIF4AIII-containing complex required for mRNA localization and nonsense-mediated mRNA decay

21 January 2018

1 reference

Splicing enhances translation in mammalian cells: an additional function of the exon junction complex

21 January 2018

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NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity

21 January 2018

1 reference

Concerted action of two dlx paralogs in sensory placode formation.

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19503078

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Pax1 and Pax9 synergistically regulate vertebral column development.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19503078

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A role for Gsh1 in the developing striatum and olfactory bulb of Gsh2 mutant mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19503078

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NSMB.1612

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Dimensions Publication ID

10 October 2017

1027660148

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1 reference