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CD4 and CD8: modulators of T-cell receptor recognition of antigen and of immune responses?
scientific article published on February 1998
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1 reference
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Europe PubMed Central
PubMed publication ID
9523116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9523116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
review article
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Europe PubMed Central
title
CD4 and CD8: modulators of T-cell receptor recognition of antigen and of immune responses?
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9523116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9523116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
author
Rose Zamoyska
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9523116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9523116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
author name string
Zamoyska R
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1
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Europe PubMed Central
PubMed publication ID
9523116
retrieved
8 October 2017
language of work or name
English
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publication date
1 February 1998
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Europe PubMed Central
PubMed publication ID
9523116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9523116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
published in
Current Opinion in Immunology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9523116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9523116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
volume
10
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9523116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9523116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
issue
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9523116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9523116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
page(s)
82-87
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9523116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9523116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
cites work
T Cell Subsets and the Recognition of MHC Class
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
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inferred from DOI database lookup
Identification of a CD4 binding site on the beta 2 domain of HLA-DR molecules.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MHC class II interaction with CD4 mediated by a region analogous to the MHC class I binding site for CD8
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell-cell adhesion mediated by CD8 and MHC class I molecules
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A binding site for the T-cell co-receptor CD8 on the alpha 3 domain of HLA-A2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complex complexes: signaling at the TCR.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Coaggregation of the T-cell receptor with CD4 and other T-cell surface molecules enhances T-cell activation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunoregulation through CD8 (Ly-2): state of aggregation with the alpha/beta/CD3 T cell receptor controls interleukin 2-dependent T cell growth
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The T cell receptor as a multicomponent signalling machine: CD4/CD8 coreceptors and CD45 in T cell activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Altered peptide ligand-induced partial T cell activation: molecular mechanisms and role in T cell biology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Making the T cell receptor go the distance: a topological view of T cell activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of an HIV-binding recombinant fragment of human CD4.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of domains 3 and 4 of rat CD4: relation to the NH2-terminal domains
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dimeric association and segmental variability in the structure of human CD4
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ligand-specific oligomerization of T-cell receptor molecules
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The two membrane proximal domains of CD4 interact with the T cell receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular biology and function of CD4 and CD8
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of a soluble form of the human T cell coreceptor CD8 at 2.6 A resolution
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of T lymphocyte positive and negative selection in mice lacking the CD8 beta chain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduced thymic maturation but normal effector function of CD8+ T cells in CD8 beta gene-targeted mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD8 beta chain influences CD8 alpha chain-associated Lck kinase activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD8 beta increases CD8 coreceptor function and participation in TCR-ligand binding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The roles of CD8 in cytotoxic T lymphocyte function
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD8 modulation of T-cell antigen receptor–ligand interactions on living cytotoxic T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytoskeletal function in CD8- and T cell receptor-mediated interaction of cytotoxic T lymphocytes with class I protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD8 is needed for development of cytotoxic T cells but not helper T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Helper T-cell development in the absence of CD4-p56 Ick association
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The lack of CD8 alpha cytoplasmic domain resulted in a dramatic decrease in efficiency in thymic maturation but only a moderate reduction in cytotoxic function of CD8+ T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD8 lineage commitment in the absence of CD8.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peptide-induced positive selection of TCR transgenic thymocytes in a coreceptor-independent manner.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD8 expression alters the fine specificity of an alloreactive MHC class I-specific T hybridoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of CD4 and CD8 in T cell activation and differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cell receptor antagonists and partial agonists
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The CD8 beta polypeptide is required for the recognition of an altered peptide ligand as an agonist
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endogenous altered peptide ligands can affect peripheral T cell responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The efficiency of CD4 recruitment to ligand-engaged TCR controls the agonist/partial agonist properties of peptide-MHC molecule ligands
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reprogramming the immune system for peripheral tolerance with CD4 and CD8 monoclonal antibodies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Anti-CD4 monoclonal antibodies in therapy: creation of nonclassical tolerance in the adult
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nonmitogenic anti-CD3 monoclonal antibodies deliver a partial T cell receptor signal and induce clonal anergy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Impaired Th2 subset development in the absence of CD4.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Is CD8 dependence a true reflection of TCR affinity for antigen?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The degree of CD8 dependence of cytolytic T cell precursors is determined by the nature of the T cell receptor (TCR) and influences negative selection in TCR-transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alterations in CD4 dependence accompany T cell development and differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The three-dimensional structure of a T-cell antigen receptor V alpha V beta heterodimer reveals a novel arrangement of the V beta domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the complex between human T-cell receptor, viral peptide and HLA-A2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Co-capping studies reveal CD8/TCR interactions after capping CD8β polypeptides and intracellular associations of CD8 with p56lck
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980036-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0952-7915(98)80036-8
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9523116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9523116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
PubMed publication ID
9523116
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9523116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9523116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
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