(Q41710731)

7 October 2017

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title

Self-reactive B cells in nonautoimmune and autoimmune mice (English)

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7 October 2017

Erikson J

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7 October 2017

Mandik L

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7 October 2017

Bui A

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7 October 2017

Eaton A

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7 October 2017

Noorchashm H

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7 October 2017

Nguyen KA

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7 October 2017

Roark JH

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7 October 2017

publication date

1 January 1998

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7 October 2017

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7 October 2017

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7 October 2017

issue

1-2

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7 October 2017

page(s)

49-61

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CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+T cells

7 October 2017

cites work

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12 December 2020

Effect of bcl-2 on Fas antigen-mediated cell death

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12 December 2020

The bcl-2 gene product inhibits clonal deletion of self-reactive B lymphocytes in the periphery but not in the bone marrow

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12 December 2020

Enhanced membrane binding of autoantibodies to cultured keratinocytes of systemic lupus erythematosus patients after ultraviolet B/ultraviolet A irradiation

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12 December 2020

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

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12 December 2020

A set of closely related antibodies dominates the primary antibody response to the antigenic site CB of the A/PR/8/34 influenza virus hemagglutinin

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12 December 2020

Clonal anergy: Inhibition of antigen-driven proliferation among single B lymphocytes from tolerant animals, and partial breakage of anergy by mitogens

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12 December 2020

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12 December 2020

Murine monoclonal anti-DNA antibodies bind directly to glomerular antigens and form immune deposits

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12 December 2020

Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation

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12 December 2020

B lymphocytes may escape tolerance by revising their antigen receptors

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12 December 2020

Abnormal thymocyte development and production of autoreactive T cells in T cell receptor transgenic autoimmune mice

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12 December 2020

FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway

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12 December 2020

Inhibition of immunoglobulin gene rearrangement by the expression of a lambda 2 transgene

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12 December 2020

The fate of self-reactive B cells depends primarily on the degree of antigen receptor engagement and availability of T cell help.

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12 December 2020

Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupus

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12 December 2020

The effect of thymectomy on lupus-prone mice

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12 December 2020

Effects of the lpr mutation on elimination and inactivation of self-reactive B cells

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12 December 2020

Unique site of IgG2a and rheumatoid factor production in MRL/lpr mice

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12 December 2020

Murine models of systemic lupus erythematosus

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12 December 2020

Regulation of anti-double-stranded DNA B cells in nonautoimmune mice: localization to the T-B interface of the splenic follicle

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12 December 2020

Reduced life span of anergic self-reactive B cells in a double-transgenic model

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12 December 2020

Responsiveness of autoimmune and normal mice to nucleic acid antigens

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12 December 2020

The site and stage of anti-DNA B-cell deletion.

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12 December 2020

Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease

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12 December 2020

Deletion and editing of B cells that express antibodies to DNA

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12 December 2020

Only a small proportion of splenic B cells in adults are short-lived virgin cells

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12 December 2020

Elimination of self-reactive B lymphocytes proceeds in two stages: arrested development and cell death.

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12 December 2020

Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin

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12 December 2020

Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire.

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12 December 2020

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

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12 December 2020

Fas receptor expression on B-lineage cells

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12 December 2020

The APO-1/Fas (CD95) receptor is expressed in homozygous MRL/lpr mice

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12 December 2020

Stochastic control of anti-Sm autoantibodies in MRL/Mp-lpr/lpr mice

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12 December 2020

Receptor editing: an approach by autoreactive B cells to escape tolerance

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12 December 2020

bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation

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12 December 2020

Genetic basis for T cell recognition of a major histocompatibility complex class II-restricted neo-self peptide

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12 December 2020

Antigen-induced exclusion from follicles and anergy are separate and complementary processes that influence peripheral B cell fate

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12 December 2020

A specific intercellular pathway of apoptotic cell death is defective in the mature peripheral T cells of autoimmune lpr and gld mice

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12 December 2020

Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens

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12 December 2020

Ultraviolet light induces binding of antibodies to selected nuclear antigens on cultured human keratinocytes

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12 December 2020

Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.

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12 December 2020

Signaling thresholds and interclonal competition in preimmune B-cell selection

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12 December 2020

Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor

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12 December 2020

Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis

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12 December 2020

Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase.

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12 December 2020

Antinuclear antibodies (ANAs): diagnostically specific immune markers and clues toward the understanding of systemic autoimmunity.

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12 December 2020

Anti-CD4 monoclonal antibody therapy suppresses autoimmune disease in MRL/Mp-lpr/lpr mice

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12 December 2020

The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice

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12 December 2020

Breakdown of B cell tolerance in a mouse model of systemic lupus erythematosus

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12 December 2020

Differential effects of Bcl-2 on T and B cells in transgenic mice

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12 December 2020

B cell selection and allelic exclusion of an anti-DNA Ig transgene in MRL-lpr/lpr mice.

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12 December 2020

Anatomy of autoantibody production: Dominant localization of antibody-producing cells to T cell zones in fas-deficient mice

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12 December 2020

Endogenous circulating DNA in systemic lupus erythematosus. Occurrence as multimeric complexes bound to histone

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12 December 2020

In vitro tolerance induction of bone marrow cells: a marker for B cell maturation

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12 December 2020

Effects of altered Bcl-2 expression on B lymphocyte selection

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12 December 2020

Selection of the T cell receptor repertoire in Lpr mice

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12 December 2020

Induction of tolerance to an IgG autoantibody

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12 December 2020

Induction of various autoantibodies by mutant gene lpr in several strains of mice

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12 December 2020

Activation and negative selection of functionally distinct subsets of antibody-secreting cells by influenza hemagglutinin as a viral and a neo-self antigen.

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12 December 2020

Receptor-mediated inactivation of early B lymphocytes

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12 December 2020

The role of somatic mutation in the pathogenic anti-DNA response

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12 December 2020

IgG anti-DNA autoantibodies within an individual autoimmune mouse are the products of clonal selection

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12 December 2020

Clonal deletion of autoreactive B lymphocytes in bone marrow chimeras

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12 December 2020

Regulation of lymphocyte survival by the bcl-2 gene family

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12 December 2020

Persistence of functionally compromised anti-double-stranded DNA B cells in the periphery of non-autoimmune mice.

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12 December 2020

Analysis of central B cell tolerance in autoimmune-prone MRL/lpr mice bearing autoantibody transgenes

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12 December 2020

Receptor editing in self-reactive bone marrow B cells

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12 December 2020

Lack of allelic exclusion permits autoreactive B cells to escape deletion

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12 December 2020

Light chain contribution to specificity in anti-DNA antibodies

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12 December 2020

Protection against Fas-dependent Th1-mediated apoptosis by antigen receptor engagement in B cells.

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12 December 2020

The lupus autoantigens and the pathogenesis of systemic lupus erythematosus

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12 December 2020

Bcl–2 protects from lethal hepatic apoptosis induced by an ant–Fas antibody in mice

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12 December 2020

Fas-activated serine/threonine kinase (FAST) phosphorylates TIA-1 during Fas-mediated apoptosis

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12 December 2020

Defective expression of hematopoietic cell protein tyrosine phosphatase (HCP) in lymphoid cells blocks Fas-mediated apoptosis

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12 December 2020

Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice

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12 December 2020

Genetic and structural evidence for antigen selection of anti-DNA antibodies.

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12 December 2020

Expression and function of the murine CD95/FasR/APO‐1 receptor in relation to B cell ontogeny

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12 December 2020

Antibodies that are specific for a single amino acid interchange in a protein epitope use structurally distinct variable regions

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12 December 2020

RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death

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12 December 2020

B cells are anergic in transgenic mice that express IgM anti-DNA antibodies

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12 December 2020

Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice

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12 December 2020

In vitro tolerance induction of neonatal murine B cells

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12 December 2020

Comparison of pathogenic and non-pathogenic murine antibodies to DNA: antigen binding and structural characteristics

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12 December 2020

Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes

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12 December 2020

Treatment of murine lupus with monoclonal anti-T cell antibody

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12 December 2020

The Fas protein is expressed at high levels on CD4+CD8+ thymocytes and activated mature lymphocytes in normal mice but not in the lupus-prone strain, MRL lpr/lpr

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12 December 2020

Functional complementation of the adenovirus E1B 19-kilodalton protein with Bcl-2 in the inhibition of apoptosis in infected cells

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12 December 2020

The RNA-binding protein TIAR is translocated from the nucleus to the cytoplasm during Fas-mediated apoptotic cell death

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12 December 2020

Ig H and L chain contributions to autoimmune specificities

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12 December 2020

Identifiers

DOI

10.1007/BF02786430

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Dimensions Publication ID

7 October 2017

1053182267

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